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Murcko scaffold

1-Phenyl-1H-pyrazolo[3,4-d]pyrimidine-4-thiol scaffold

40 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
40
With full pages
3
Scaffold SMILES

S=c1nc[nH]c2c1cnn2-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Phenyl-1H-pyrazolo[3,4-d]pyrimidine-4-thiol page
Murcko scaffold S=c1nc[nH]c2c1cnn2-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 40 of 40 chemicals

6-Chloro-1-phenyl-7H-pyrazolo[5,4-d]pyrimidine-4-thione chemical structure, C11H7ClN4S, CAS 6289-00-5
6-Chloro-1-phenyl-7H-pyrazolo[5,4-d]pyrimidine-4-thione
CAS 6289-00-5C11H7ClN4S
1-Phenyl-1H-pyrazolo[3,4-d]pyrimidine-4-thiol chemical structure, C11H8N4S, CAS 6014-07-9
1-Phenyl-1H-pyrazolo[3,4-d]pyrimidine-4-thiol
CAS 6014-07-9C11H8N4S
6-Methyl-1-(4-nitrophenyl)-1H-pyrazolo[3,4-D]pyrimidine-4-thiol chemical structure, C12H9N5O2S, CAS 5399-42-8
6-Methyl-1-(4-nitrophenyl)-1H-pyrazolo[3,4-D]pyrimidine-4-thiol
CAS 5399-42-8C12H9N5O2S
3-Methyl-1-phenyl-7H-pyrazolo[5,4-d]pyrimidine-4-thione chemical structure, C12H10N4S, CAS 14246-99-2
3-Methyl-1-phenyl-7H-pyrazolo[5,4-d]pyrimidine-4-thione
CAS 14246-99-2C12H10N4S
6-Methyl-1-phenyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidine-4-thione chemical structure, C12H10N4S, CAS 5399-43-9
6-Methyl-1-phenyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidine-4-thione
CAS 5399-43-9C12H10N4S
1-(4-Chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol chemical structure, C11H7ClN4S, CAS 5334-62-3
1-(4-Chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol
CAS 5334-62-3C11H7ClN4S
2-(4-Mercapto-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-3-methyl-butyramide chemical structure, C16H17N5OS2, CAS 181702-33-0
2-(4-Mercapto-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-3-methyl-butyramide
CAS 181702-33-0C16H17N5OS2
6-Ethyl-1-phenyl-1H-pyrazolo[3,4-D]pyrimidine-4-thiol chemical structure, C13H12N4S, CAS 100396-57-4
6-Ethyl-1-phenyl-1H-pyrazolo[3,4-D]pyrimidine-4-thiol
CAS 100396-57-4C13H12N4S
1-(4-Fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol chemical structure, C11H7FN4S, CAS 924022-47-9
1-(4-Fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol
CAS 924022-47-9C11H7FN4S
6-Isopropyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine-4-thiol chemical structure, C14H14N4S, CAS 917749-34-9
6-Isopropyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine-4-thiol
CAS 917749-34-9C14H14N4S
1-(4-Methylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol chemical structure, C12H10N4S, CAS 891387-36-3
1-(4-Methylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol
CAS 891387-36-3C12H10N4S
1-(4-Bromophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol chemical structure, C11H7BrN4S, CAS 893725-41-2
1-(4-Bromophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol
CAS 893725-41-2C11H7BrN4S
1-Phenyl-3-methyl-6-trifluoromethyl-pyrazolo(3,4-d)pyrimidine-4(5H)thione chemical structure, C13H9F3N4S, CAS 102989-83-3
1-Phenyl-3-methyl-6-trifluoromethyl-pyrazolo(3,4-d)pyrimidine-4(5H)thione
CAS 102989-83-3C13H9F3N4S
1-(3-Chlorophenyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidine-4-thione chemical structure, C11H7ClN4S, CAS 941868-10-6
1-(3-Chlorophenyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidine-4-thione
CAS 941868-10-6C11H7ClN4S
1-(m-Tolyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol chemical structure, C12H10N4S, CAS 1082528-86-6
1-(m-Tolyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol
CAS 1082528-86-6C12H10N4S
1-(2,4-Dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol chemical structure, C13H12N4S, CAS 1082367-11-0
1-(2,4-Dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol
CAS 1082367-11-0C13H12N4S
1-(2,5-Dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol chemical structure, C13H12N4S, CAS 1082437-00-0
1-(2,5-Dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol
CAS 1082437-00-0C13H12N4S
1-(3,5-Dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol chemical structure, C13H12N4S, CAS 1082528-87-7
1-(3,5-Dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol
CAS 1082528-87-7C13H12N4S
1-(2,3-Dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol chemical structure, C13H12N4S, CAS 1082437-01-1
1-(2,3-Dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol
CAS 1082437-01-1C13H12N4S
1-(4-Ethylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol chemical structure, C13H12N4S, CAS 1082584-36-8
1-(4-Ethylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol
CAS 1082584-36-8C13H12N4S
1-(4-Isopropylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol chemical structure, C14H14N4S, CAS 1082528-88-8
1-(4-Isopropylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol
CAS 1082528-88-8C14H14N4S
1-(2-Fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol chemical structure, C11H7FN4S, CAS 1082584-37-9
1-(2-Fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol
CAS 1082584-37-9C11H7FN4S
1-(2-Chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol chemical structure, C11H7ClN4S, CAS 1082528-89-9
1-(2-Chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol
CAS 1082528-89-9C11H7ClN4S
1-(3-Chloro-2-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol chemical structure, C12H9ClN4S, CAS 1082437-03-3
1-(3-Chloro-2-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol
CAS 1082437-03-3C12H9ClN4S