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Murcko scaffold

2-Phenyl-5-(thiophen-2-yl)-1,3,4-oxadiazole scaffold

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
16
With full pages
6
Scaffold SMILES

c1ccc(-c2nnc(-c3cccs3)o2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Phenyl-5-(thiophen-2-yl)-1,3,4-oxadiazole page
Murcko scaffold c1ccc(-c2nnc(-c3cccs3)o2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

2-Phenyl-5-(thiophen-2-yl)-1,3,4-oxadiazole chemical structure, C12H8N2OS, CAS 65183-21-3
2-Phenyl-5-(thiophen-2-yl)-1,3,4-oxadiazole
CAS 65183-21-3C12H8N2OS
2-Thiophen-2-yl-5-(3,4,5-trimethoxyphenyl)-1,3,4-oxadiazole chemical structure, C15H14N2O4S, CAS 313382-57-9
2-Thiophen-2-yl-5-(3,4,5-trimethoxyphenyl)-1,3,4-oxadiazole
CAS 313382-57-9C15H14N2O4S
2-(2-Methoxyphenyl)-5-(2-thienyl)-1,3,4-oxadiazole chemical structure, C13H10N2O2S, CAS 671793-69-4
2-(2-Methoxyphenyl)-5-(2-thienyl)-1,3,4-oxadiazole
CAS 671793-69-4C13H10N2O2S
1,3,4-Oxadiazole, 2-(4-methylphenyl)-5-(2-thienyl)- chemical structure, C13H10N2OS, CAS 110380-38-6
1,3,4-Oxadiazole, 2-(4-methylphenyl)-5-(2-thienyl)-
CAS 110380-38-6C13H10N2OS
2-(3-Chlorophenyl)-5-thiophen-2-yl-1,3,4-oxadiazole chemical structure, C12H7ClN2OS, CAS 331987-47-4
2-(3-Chlorophenyl)-5-thiophen-2-yl-1,3,4-oxadiazole
CAS 331987-47-4C12H7ClN2OS
2-(4-Chlorophenyl)-5-(2-thienyl)-1,3,4-oxadiazole chemical structure, C12H7ClN2OS, CAS 294652-11-2
2-(4-Chlorophenyl)-5-(2-thienyl)-1,3,4-oxadiazole
CAS 294652-11-2C12H7ClN2OS
2-(2,4-Dichlorophenyl)-5-(2-thienyl)-1,3,4-oxadiazole chemical structure, C12H6Cl2N2OS, CAS 478260-89-8
2-(2,4-Dichlorophenyl)-5-(2-thienyl)-1,3,4-oxadiazole
CAS 478260-89-8C12H6Cl2N2OS
2-(2-Methylphenyl)-5-(thiophen-2-yl)-1,3,4-oxadiazole chemical structure, C13H10N2OS, CAS 478260-90-1
2-(2-Methylphenyl)-5-(thiophen-2-yl)-1,3,4-oxadiazole
CAS 478260-90-1C13H10N2OS
2-(3-Chlorothiophen-2-yl)-5-(2-(trifluoromethyl)phenyl)-1,3,4-oxadiazole chemical structure, C13H6ClF3N2OS, CAS 710280-14-1
2-(3-Chlorothiophen-2-yl)-5-(2-(trifluoromethyl)phenyl)-1,3,4-oxadiazole
CAS 710280-14-1C13H6ClF3N2OS
2-(2-Chlorophenyl)-5-(thiophen-2-yl)-1,3,4-oxadiazole chemical structure, C12H7ClN2OS, CAS 331987-49-6
2-(2-Chlorophenyl)-5-(thiophen-2-yl)-1,3,4-oxadiazole
CAS 331987-49-6C12H7ClN2OS
1,3,4-Oxadiazole, 2-[4-(1,1-dimethylethyl)phenyl]-5-(5-iodo-2-thienyl)- chemical structure, C16H15IN2OS, CAS 819863-79-1
1,3,4-Oxadiazole, 2-[4-(1,1-dimethylethyl)phenyl]-5-(5-iodo-2-thienyl)-
CAS 819863-79-1C16H15IN2OS
Benzenamine, 3-[5-(2-thienyl)-1,3,4-oxadiazol-2-yl]- chemical structure, C12H9N3OS, CAS 1011407-22-9
Benzenamine, 3-[5-(2-thienyl)-1,3,4-oxadiazol-2-yl]-
CAS 1011407-22-9C12H9N3OS
4-[5-(Thiophen-2-yl)-1,3,4-oxadiazol-2-yl]aniline chemical structure, C12H9N3OS, CAS 110380-40-0
4-[5-(Thiophen-2-yl)-1,3,4-oxadiazol-2-yl]aniline
CAS 110380-40-0C12H9N3OS
2-(3-Bromophenyl)-5-(thiophen-2-yl)-1,3,4-oxadiazole chemical structure, C12H7BrN2OS, CAS 957065-93-9
2-(3-Bromophenyl)-5-(thiophen-2-yl)-1,3,4-oxadiazole
CAS 957065-93-9C12H7BrN2OS
{3-[5-(Thiophen-2-yl)-1,3,4-oxadiazol-2-yl]phenyl}boronic acid chemical structure, C12H9BN2O3S, CAS 2377609-61-3
{3-[5-(Thiophen-2-yl)-1,3,4-oxadiazol-2-yl]phenyl}boronic acid
CAS 2377609-61-3C12H9BN2O3S
2-(5-(Thiophen-2-yl)-1,3,4-oxadiazol-2-yl)aniline chemical structure, C12H9N3OS, CAS 1334629-68-3
2-(5-(Thiophen-2-yl)-1,3,4-oxadiazol-2-yl)aniline
CAS 1334629-68-3C12H9N3OS