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Murcko scaffold

Ring system with 3 rings and 20 atoms

40 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
40
With full pages
11
Scaffold SMILES

O=C(Nc1ccccc1)c1cnn(-c2ccccc2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1cnn(-c2ccccc2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 40 of 40 chemicals

5-Chloro-N-(4-methoxyphenyl)-3-methyl-1-phenylpyrazole-4-carboxamide chemical structure, C18H16ClN3O2, CAS 302560-93-6
5-Chloro-N-(4-methoxyphenyl)-3-methyl-1-phenylpyrazole-4-carboxamide
CAS 302560-93-6C18H16ClN3O2
5-Chloro-N-(2,4-dimethylphenyl)-3-methyl-1-phenyl-1H-pyrazole-4-carboxamide chemical structure, C19H18ClN3O, CAS 302561-02-0
5-Chloro-N-(2,4-dimethylphenyl)-3-methyl-1-phenyl-1H-pyrazole-4-carboxamide
CAS 302561-02-0C19H18ClN3O
5-Amino-N,1-diphenylpyrazole-4-carboxamide chemical structure, C16H14N4O, CAS 497161-22-5
5-Amino-N,1-diphenylpyrazole-4-carboxamide
CAS 497161-22-5C16H14N4O
5-Methyl-N-(3-nitrophenyl)-1-phenylpyrazole-4-carboxamide chemical structure, C17H14N4O3, CAS 302939-41-9
5-Methyl-N-(3-nitrophenyl)-1-phenylpyrazole-4-carboxamide
CAS 302939-41-9C17H14N4O3
N-(3-Fluorophenyl)-5-methyl-1-phenylpyrazole-4-carboxamide chemical structure, C17H14FN3O, CAS 955963-91-4
N-(3-Fluorophenyl)-5-methyl-1-phenylpyrazole-4-carboxamide
CAS 955963-91-4C17H14FN3O
N-(3-Acetylphenyl)-5-methyl-1-phenylpyrazole-4-carboxamide chemical structure, C19H17N3O2, CAS 956740-82-2
N-(3-Acetylphenyl)-5-methyl-1-phenylpyrazole-4-carboxamide
CAS 956740-82-2C19H17N3O2
N-(2,6-Dimethylphenyl)-5-methyl-1-phenyl-1H-pyrazole-4-carboxamide chemical structure, C19H19N3O, CAS 957478-43-2
N-(2,6-Dimethylphenyl)-5-methyl-1-phenyl-1H-pyrazole-4-carboxamide
CAS 957478-43-2C19H19N3O
5-Chloro-N-(3-chloro-2-methylphenyl)-3-methyl-1-phenyl-1H-pyrazole-4-carboxamide chemical structure, C18H15Cl2N3O, CAS 353464-53-6
5-Chloro-N-(3-chloro-2-methylphenyl)-3-methyl-1-phenyl-1H-pyrazole-4-carboxamide
CAS 353464-53-6C18H15Cl2N3O
5-Chloro-3-methyl-1-phenyl-N-[3-(trifluoromethyl)phenyl]-1H-pyrazole-4-carboxamide chemical structure, C18H13ClF3N3O, CAS 296262-13-0
5-Chloro-3-methyl-1-phenyl-N-[3-(trifluoromethyl)phenyl]-1H-pyrazole-4-carboxamide
CAS 296262-13-0C18H13ClF3N3O
5-Chloro-N-(2,5-dichlorophenyl)-3-methyl-1-phenyl-1H-pyrazole-4-carboxamide chemical structure, C17H12Cl3N3O, CAS 302561-04-2
5-Chloro-N-(2,5-dichlorophenyl)-3-methyl-1-phenyl-1H-pyrazole-4-carboxamide
CAS 302561-04-2C17H12Cl3N3O
5-Chloro-N-(2-methoxy-5-nitrophenyl)-3-methyl-1-phenyl-1H-pyrazole-4-carboxamide chemical structure, C18H15ClN4O4, CAS 328251-85-0
5-Chloro-N-(2-methoxy-5-nitrophenyl)-3-methyl-1-phenyl-1H-pyrazole-4-carboxamide
CAS 328251-85-0C18H15ClN4O4
N-(4-Acetamidophenyl)-5-chloro-3-methyl-1-phenylpyrazole-4-carboxamide chemical structure, C19H17ClN4O2, CAS 302561-03-1
N-(4-Acetamidophenyl)-5-chloro-3-methyl-1-phenylpyrazole-4-carboxamide
CAS 302561-03-1C19H17ClN4O2
5-Amino-1-(2-fluorophenyl)-N-[3-(trifluoromethyl)phenyl]-1H-pyrazole-4-carboxamide chemical structure, C17H12F4N4O, CAS 955964-66-6
5-Amino-1-(2-fluorophenyl)-N-[3-(trifluoromethyl)phenyl]-1H-pyrazole-4-carboxamide
CAS 955964-66-6C17H12F4N4O
5-Chloro-N-(2-methoxyphenyl)-3-methyl-1-phenylpyrazole-4-carboxamide chemical structure, C18H16ClN3O2, CAS 311809-90-2
5-Chloro-N-(2-methoxyphenyl)-3-methyl-1-phenylpyrazole-4-carboxamide
CAS 311809-90-2C18H16ClN3O2
5-Chloro-N-(3-methoxyphenyl)-3-methyl-1-phenylpyrazole-4-carboxamide chemical structure, C18H16ClN3O2, CAS 311809-85-5
5-Chloro-N-(3-methoxyphenyl)-3-methyl-1-phenylpyrazole-4-carboxamide
CAS 311809-85-5C18H16ClN3O2
3,5-Dimethyl-N,1-diphenylpyrazole-4-carboxamide chemical structure, C18H17N3O, CAS 61747-92-0
3,5-Dimethyl-N,1-diphenylpyrazole-4-carboxamide
CAS 61747-92-0C18H17N3O
N-(4-Chlorophenyl)-1-phenyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide chemical structure, C17H11ClF3N3O, CAS 521927-29-7
N-(4-Chlorophenyl)-1-phenyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide
CAS 521927-29-7C17H11ClF3N3O
N-[5-(Dimethylsulfamoyl)-2-methylphenyl]-1-phenyl-5-propyl-1H-pyrazole-4-carboxamide chemical structure, C22H26N4O3S, CAS 698974-57-1
N-[5-(Dimethylsulfamoyl)-2-methylphenyl]-1-phenyl-5-propyl-1H-pyrazole-4-carboxamide
CAS 698974-57-1C22H26N4O3S
5-Chloro-3-methyl-N-(3-methylphenyl)-1-phenylpyrazole-4-carboxamide chemical structure, C18H16ClN3O, CAS 356564-60-8
5-Chloro-3-methyl-N-(3-methylphenyl)-1-phenylpyrazole-4-carboxamide
CAS 356564-60-8C18H16ClN3O
N-(4-Methoxyphenyl)-1-phenyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide chemical structure, C18H14F3N3O2, CAS 956742-03-3
N-(4-Methoxyphenyl)-1-phenyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide
CAS 956742-03-3C18H14F3N3O2
N-(3,4-Dimethylphenyl)-1-phenyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide chemical structure, C19H16F3N3O, CAS 956612-52-5
N-(3,4-Dimethylphenyl)-1-phenyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide
CAS 956612-52-5C19H16F3N3O
N-(4-Fluorophenyl)-1-phenyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide chemical structure, C17H11F4N3O, CAS 956977-51-8
N-(4-Fluorophenyl)-1-phenyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide
CAS 956977-51-8C17H11F4N3O
N-(2,4-Difluorophenyl)-1-phenyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide chemical structure, C17H10F5N3O, CAS 956507-86-1
N-(2,4-Difluorophenyl)-1-phenyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide
CAS 956507-86-1C17H10F5N3O
N-(4-Methoxyphenyl)-1-phenyl-1H-pyrazole-4-carboxamide chemical structure, C17H15N3O2, CAS 267641-99-6
N-(4-Methoxyphenyl)-1-phenyl-1H-pyrazole-4-carboxamide
CAS 267641-99-6C17H15N3O2