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Murcko scaffold

1-(1-Benzylpiperidin-4-yl)-4-phenylpiperazine scaffold

58 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
58
With full pages
2
Scaffold SMILES

c1ccc(CN2CCC(N3CCN(c4ccccc4)CC3)CC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(1-Benzylpiperidin-4-yl)-4-phenylpiperazine page
Murcko scaffold c1ccc(CN2CCC(N3CCN(c4ccccc4)CC3)CC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 58 of 58 chemicals

1-Phenyl-4-[1-[(2,3,4-trimethoxyphenyl)methyl]piperidin-4-yl]piperazine chemical structure, C25H35N3O3, CAS 792927-27-6
1-Phenyl-4-[1-[(2,3,4-trimethoxyphenyl)methyl]piperidin-4-yl]piperazine
CAS 792927-27-6C25H35N3O3
1-[1-[(3,4-Dimethoxyphenyl)methyl]piperidin-4-yl]-4-(2-methoxyphenyl)piperazine chemical structure, C25H35N3O3, CAS 792928-22-4
1-[1-[(3,4-Dimethoxyphenyl)methyl]piperidin-4-yl]-4-(2-methoxyphenyl)piperazine
CAS 792928-22-4C25H35N3O3
1-[1-[(2,4-Dimethoxyphenyl)methyl]piperidin-4-yl]-4-(2-methoxyphenyl)piperazine chemical structure, C25H35N3O3, CAS 497231-83-1
1-[1-[(2,4-Dimethoxyphenyl)methyl]piperidin-4-yl]-4-(2-methoxyphenyl)piperazine
CAS 497231-83-1C25H35N3O3
1-(1-Benzylpiperidin-4-yl)-4-(4-fluorophenyl)piperazine chemical structure, C22H28FN3, CAS 416861-39-7
1-(1-Benzylpiperidin-4-yl)-4-(4-fluorophenyl)piperazine
CAS 416861-39-7C22H28FN3
1-(1-Benzylpiperidin-4-yl)-4-phenylpiperazine chemical structure, C22H29N3, CAS 416870-81-0
1-(1-Benzylpiperidin-4-yl)-4-phenylpiperazine
CAS 416870-81-0C22H29N3
1-[1-[(2-Bromophenyl)methyl]piperidin-4-yl]-4-phenylpiperazine, oxalic acid chemical structure, C24H30BrN3O4, CAS 1048343-84-5
1-[1-[(2-Bromophenyl)methyl]piperidin-4-yl]-4-phenylpiperazine, oxalic acid
CAS 1048343-84-5C24H30BrN3O4
2,6-Dimethoxy-4-[[4-(4-phenylpiperazin-1-yl)piperidin-1-yl]methyl]phenol, oxalic acid chemical structure, C26H35N3O7, CAS 1048343-85-6
2,6-Dimethoxy-4-[[4-(4-phenylpiperazin-1-yl)piperidin-1-yl]methyl]phenol, oxalic acid
CAS 1048343-85-6C26H35N3O7
1-(1-Benzylpiperidin-4-yl)-4-(3-methoxyphenyl)piperazine chemical structure, C23H31N3O, CAS 331978-48-4
1-(1-Benzylpiperidin-4-yl)-4-(3-methoxyphenyl)piperazine
CAS 331978-48-4C23H31N3O
Methyl 3-{1-benzyl-4-[4-(2-methoxyphenyl)piperazin-1-yl]piperidin-3-yl}propanoate chemical structure, C27H37N3O3, CAS 1134331-51-3
Methyl 3-{1-benzyl-4-[4-(2-methoxyphenyl)piperazin-1-yl]piperidin-3-yl}propanoate
CAS 1134331-51-3C27H37N3O3
Methyl 3-(1-benzyl-4-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}piperidin-3-yl)propanoate chemical structure, C27H34F3N3O2, CAS 1134331-53-5
Methyl 3-(1-benzyl-4-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}piperidin-3-yl)propanoate
CAS 1134331-53-5C27H34F3N3O2