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Murcko scaffold

Ring system with 2 rings and 16 atoms

15 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
15
With full pages
3
Scaffold SMILES

O=C(CCc1ccccc1)Nc1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CCc1ccccc1)Nc1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

N-(3-Cyano-4,5-dimethylthiophen-2-yl)-3-phenylpropanamide chemical structure, C16H16N2OS, CAS 329219-39-8
N-(3-Cyano-4,5-dimethylthiophen-2-yl)-3-phenylpropanamide
CAS 329219-39-8C16H16N2OS
4,5-Dimethyl-2-(3-phenylpropanamido)thiophene-3-carboxamide chemical structure, C16H18N2O2S, CAS 346720-15-8
4,5-Dimethyl-2-(3-phenylpropanamido)thiophene-3-carboxamide
CAS 346720-15-8C16H18N2O2S
4-Ethyl-5-methyl-2-(3-phenylpropanoylamino)thiophene-3-carboxamide chemical structure, C17H20N2O2S, CAS 424811-95-0
4-Ethyl-5-methyl-2-(3-phenylpropanoylamino)thiophene-3-carboxamide
CAS 424811-95-0C17H20N2O2S
Propan-2-yl 4-carbamoyl-3-methyl-5-(3-phenylpropanoylamino)thiophene-2-carboxylate chemical structure, C19H22N2O4S, CAS 353766-10-6
Propan-2-yl 4-carbamoyl-3-methyl-5-(3-phenylpropanoylamino)thiophene-2-carboxylate
CAS 353766-10-6C19H22N2O4S
Propan-2-yl 5-(diethylcarbamoyl)-4-methyl-2-(3-phenylpropanoylamino)thiophene-3-carboxylate chemical structure, C23H30N2O4S, CAS 309950-18-3
Propan-2-yl 5-(diethylcarbamoyl)-4-methyl-2-(3-phenylpropanoylamino)thiophene-3-carboxylate
CAS 309950-18-3C23H30N2O4S
Ethyl 4-cyano-3-methyl-5-(3-phenylpropanamido)thiophene-2-carboxylate chemical structure, C18H18N2O3S, CAS 449177-13-3
Ethyl 4-cyano-3-methyl-5-(3-phenylpropanamido)thiophene-2-carboxylate
CAS 449177-13-3C18H18N2O3S
4,5-Dimethyl-2-(3-phenylpropanamido)thiophene-3-carboxylic acid chemical structure, C16H17NO3S, CAS 312940-47-9
4,5-Dimethyl-2-(3-phenylpropanamido)thiophene-3-carboxylic acid
CAS 312940-47-9C16H17NO3S
Methyl 4-ethyl-5-methyl-2-(3-phenylpropanoylamino)thiophene-3-carboxylate chemical structure, C18H21NO3S, CAS 418785-71-4
Methyl 4-ethyl-5-methyl-2-(3-phenylpropanoylamino)thiophene-3-carboxylate
CAS 418785-71-4C18H21NO3S
Dimethyl 3-methyl-5-(3-phenylpropanoylamino)thiophene-2,4-dicarboxylate chemical structure, C18H19NO5S, CAS 6128-31-0
Dimethyl 3-methyl-5-(3-phenylpropanoylamino)thiophene-2,4-dicarboxylate
CAS 6128-31-0C18H19NO5S
2-(3-Phenylpropanoylamino)thiophene-3-carboxamide chemical structure, C14H14N2O2S, CAS 895944-45-3
2-(3-Phenylpropanoylamino)thiophene-3-carboxamide
CAS 895944-45-3C14H14N2O2S
Methyl 2-(3-phenylpropanamido)thiophene-3-carboxylate chemical structure, C15H15NO3S, CAS 864940-34-1
Methyl 2-(3-phenylpropanamido)thiophene-3-carboxylate
CAS 864940-34-1C15H15NO3S
Methyl 4,5-dimethyl-2-(3-phenylpropanamido)thiophene-3-carboxylate chemical structure, C17H19NO3S, CAS 544666-72-0
Methyl 4,5-dimethyl-2-(3-phenylpropanamido)thiophene-3-carboxylate
CAS 544666-72-0C17H19NO3S
N,4,5-trimethyl-2-(3-phenylpropanamido)thiophene-3-carboxamide chemical structure, C17H20N2O2S, CAS 896298-95-6
N,4,5-trimethyl-2-(3-phenylpropanamido)thiophene-3-carboxamide
CAS 896298-95-6C17H20N2O2S
Ethyl 3-methyl-5-(3-phenylpropanamido)-4-thiocyanatothiophene-2-carboxylate chemical structure, C18H18N2O3S2, CAS 681163-42-8
Ethyl 3-methyl-5-(3-phenylpropanamido)-4-thiocyanatothiophene-2-carboxylate
CAS 681163-42-8C18H18N2O3S2
(S)-2-Amino-3-phenyl-N-(thiophen-2-yl)propanamide chemical structure, C13H14N2OS, CAS 1449688-88-3
(S)-2-Amino-3-phenyl-N-(thiophen-2-yl)propanamide
CAS 1449688-88-3C13H14N2OS