CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 26 atoms

14 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
14
With full pages
3
Scaffold SMILES

O=S(=O)(Cc1nc2ccccc2nc1N1CCCCC1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(Cc1nc2ccccc2nc1N1CCCCC1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

2-(Benzenesulfonyl)-2-[3-(3-methylpiperidin-1-yl)quinoxalin-2-yl]acetonitrile chemical structure, C22H22N4O2S, CAS 840510-32-9
2-(Benzenesulfonyl)-2-[3-(3-methylpiperidin-1-yl)quinoxalin-2-yl]acetonitrile
CAS 840510-32-9C22H22N4O2S
2-(4-Methylphenyl)sulfonyl-2-(3-piperidin-1-ylquinoxalin-2-yl)acetonitrile chemical structure, C22H22N4O2S, CAS 300376-84-5
2-(4-Methylphenyl)sulfonyl-2-(3-piperidin-1-ylquinoxalin-2-yl)acetonitrile
CAS 300376-84-5C22H22N4O2S
2-((4-Methoxyphenyl)sulfonyl)-2-(3-(piperidin-1-yl)quinoxalin-2-yl)acetonitrile chemical structure, C22H22N4O3S, CAS 846593-89-3
2-((4-Methoxyphenyl)sulfonyl)-2-(3-(piperidin-1-yl)quinoxalin-2-yl)acetonitrile
CAS 846593-89-3C22H22N4O3S
2-(4-Methoxyphenyl)sulfonyl-2-[3-(4-methylpiperidin-1-yl)quinoxalin-2-yl]acetonitrile chemical structure, C23H24N4O3S, CAS 847378-62-5
2-(4-Methoxyphenyl)sulfonyl-2-[3-(4-methylpiperidin-1-yl)quinoxalin-2-yl]acetonitrile
CAS 847378-62-5C23H24N4O3S
2-((3-Chlorophenyl)sulfonyl)-2-(3-(piperidin-1-yl)quinoxalin-2-yl)acetonitrile chemical structure, C21H19ClN4O2S, CAS 844448-76-6
2-((3-Chlorophenyl)sulfonyl)-2-(3-(piperidin-1-yl)quinoxalin-2-yl)acetonitrile
CAS 844448-76-6C21H19ClN4O2S
2-(3-(Piperidin-1-yl)quinoxalin-2-yl)-2-(m-tolylsulfonyl)acetonitrile chemical structure, C22H22N4O2S, CAS 847161-10-8
2-(3-(Piperidin-1-yl)quinoxalin-2-yl)-2-(m-tolylsulfonyl)acetonitrile
CAS 847161-10-8C22H22N4O2S
2-(3-(4-Methylpiperidin-1-yl)quinoxalin-2-yl)-2-(m-tolylsulfonyl)acetonitrile chemical structure, C23H24N4O2S, CAS 848217-11-8
2-(3-(4-Methylpiperidin-1-yl)quinoxalin-2-yl)-2-(m-tolylsulfonyl)acetonitrile
CAS 848217-11-8C23H24N4O2S
2-((4-Fluorophenyl)sulfonyl)-2-(3-(3-methylpiperidin-1-yl)quinoxalin-2-yl)acetonitrile chemical structure, C22H21FN4O2S, CAS 848919-05-1
2-((4-Fluorophenyl)sulfonyl)-2-(3-(3-methylpiperidin-1-yl)quinoxalin-2-yl)acetonitrile
CAS 848919-05-1C22H21FN4O2S
(3,4-Dimethylbenzene-1-sulfonyl)[3-(3-methylpiperidin-1-yl)quinoxalin-2-yl]acetonitrile chemical structure, C24H26N4O2S, CAS 847377-74-6
(3,4-Dimethylbenzene-1-sulfonyl)[3-(3-methylpiperidin-1-yl)quinoxalin-2-yl]acetonitrile
CAS 847377-74-6C24H26N4O2S
2-(3-(3-Methylpiperidin-1-yl)quinoxalin-2-yl)-2-(m-tolylsulfonyl)acetonitrile chemical structure, C23H24N4O2S, CAS 847184-51-4
2-(3-(3-Methylpiperidin-1-yl)quinoxalin-2-yl)-2-(m-tolylsulfonyl)acetonitrile
CAS 847184-51-4C23H24N4O2S
2-((3-Chlorophenyl)sulfonyl)-2-(3-(4-methylpiperidin-1-yl)quinoxalin-2-yl)acetonitrile chemical structure, C22H21ClN4O2S, CAS 847379-36-6
2-((3-Chlorophenyl)sulfonyl)-2-(3-(4-methylpiperidin-1-yl)quinoxalin-2-yl)acetonitrile
CAS 847379-36-6C22H21ClN4O2S
2-((2,5-Dimethylphenyl)sulfonyl)-2-(3-(piperidin-1-yl)quinoxalin-2-yl)acetonitrile chemical structure, C23H24N4O2S, CAS 845632-44-2
2-((2,5-Dimethylphenyl)sulfonyl)-2-(3-(piperidin-1-yl)quinoxalin-2-yl)acetonitrile
CAS 845632-44-2C23H24N4O2S
2-(2,5-Dimethylphenyl)sulfonyl-2-[3-(3-methylpiperidin-1-yl)quinoxalin-2-yl]acetonitrile chemical structure, C24H26N4O2S, CAS 847175-99-9
2-(2,5-Dimethylphenyl)sulfonyl-2-[3-(3-methylpiperidin-1-yl)quinoxalin-2-yl]acetonitrile
CAS 847175-99-9C24H26N4O2S
2-((2,5-Dimethylphenyl)sulfonyl)-2-(3-(4-methylpiperidin-1-yl)quinoxalin-2-yl)acetonitrile chemical structure, C24H26N4O2S, CAS 844659-77-4
2-((2,5-Dimethylphenyl)sulfonyl)-2-(3-(4-methylpiperidin-1-yl)quinoxalin-2-yl)acetonitrile
CAS 844659-77-4C24H26N4O2S