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Murcko scaffold

Ring system with 4 rings and 25 atoms

16 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
16
With full pages
7
Scaffold SMILES

O=c1c2ccccc2nc(C=Cc2ccccn2)n1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c2ccccc2nc(C=Cc2ccccn2)n1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

3-(2-Methylphenyl)-2-(2-(2-pyridinyl)ethenyl)-4(3H)-quinazolinone chemical structure, C22H17N3O, CAS 1897-89-8
3-(2-Methylphenyl)-2-(2-(2-pyridinyl)ethenyl)-4(3H)-quinazolinone
CAS 1897-89-8C22H17N3O
6-Iodo-3-(3-methoxyphenyl)-2-[(E)-2-pyridin-2-ylethenyl]quinazolin-4-one chemical structure, C22H16IN3O2, CAS 702650-36-0
6-Iodo-3-(3-methoxyphenyl)-2-[(E)-2-pyridin-2-ylethenyl]quinazolin-4-one
CAS 702650-36-0C22H16IN3O2
3-(4-Chloro-2-nitrophenyl)-6-iodo-2-[(E)-2-pyridin-2-ylethenyl]quinazolin-4-one chemical structure, C21H12ClIN4O3, CAS 708992-71-6
3-(4-Chloro-2-nitrophenyl)-6-iodo-2-[(E)-2-pyridin-2-ylethenyl]quinazolin-4-one
CAS 708992-71-6C21H12ClIN4O3
3-Phenyl-2-[(E)-2-pyridin-2-ylethenyl]quinazolin-4-one chemical structure, C21H15N3O, CAS 1399983-58-4
3-Phenyl-2-[(E)-2-pyridin-2-ylethenyl]quinazolin-4-one
CAS 1399983-58-4C21H15N3O
3-(4-Bromophenyl)-2-[(E)-2-pyridin-2-ylethenyl]quinazolin-4-one chemical structure, C21H14BrN3O, CAS 838889-85-3
3-(4-Bromophenyl)-2-[(E)-2-pyridin-2-ylethenyl]quinazolin-4-one
CAS 838889-85-3C21H14BrN3O
3-(4-Methoxyphenyl)-2-[(E)-2-pyridin-2-ylethenyl]quinazolin-4-one chemical structure, C22H17N3O2, CAS 799260-36-9
3-(4-Methoxyphenyl)-2-[(E)-2-pyridin-2-ylethenyl]quinazolin-4-one
CAS 799260-36-9C22H17N3O2
3-(2,6-Dichlorophenyl)-2-[(E)-2-pyridin-2-ylethenyl]quinazolin-4-one chemical structure, C21H13Cl2N3O, CAS 334542-10-8
3-(2,6-Dichlorophenyl)-2-[(E)-2-pyridin-2-ylethenyl]quinazolin-4-one
CAS 334542-10-8C21H13Cl2N3O
3-(3-Methylphenyl)-2-[(E)-2-pyridin-2-ylethenyl]quinazolin-4-one chemical structure, C22H17N3O, CAS 799260-35-8
3-(3-Methylphenyl)-2-[(E)-2-pyridin-2-ylethenyl]quinazolin-4-one
CAS 799260-35-8C22H17N3O
3-(4-Methylphenyl)-2-[(E)-2-pyridin-2-ylethenyl]quinazolin-4-one chemical structure, C22H17N3O, CAS 389075-08-5
3-(4-Methylphenyl)-2-[(E)-2-pyridin-2-ylethenyl]quinazolin-4-one
CAS 389075-08-5C22H17N3O
3-(4-Chlorophenyl)-2-[(E)-2-pyridin-2-ylethenyl]quinazolin-4-one chemical structure, C21H14ClN3O, CAS 799260-38-1
3-(4-Chlorophenyl)-2-[(E)-2-pyridin-2-ylethenyl]quinazolin-4-one
CAS 799260-38-1C21H14ClN3O
3-(3-Methoxyphenyl)-2-[(E)-2-pyridin-2-ylethenyl]quinazolin-4-one chemical structure, C22H17N3O2, CAS 799260-39-2
3-(3-Methoxyphenyl)-2-[(E)-2-pyridin-2-ylethenyl]quinazolin-4-one
CAS 799260-39-2C22H17N3O2
3-(2-Methoxyphenyl)-2-[(E)-2-pyridin-2-ylethenyl]quinazolin-4-one chemical structure, C22H17N3O2, CAS 334542-07-3
3-(2-Methoxyphenyl)-2-[(E)-2-pyridin-2-ylethenyl]quinazolin-4-one
CAS 334542-07-3C22H17N3O2
Piricualona chemical structure, C22H17N3O, CAS 1781252-58-1
Piricualona
CAS 1781252-58-1C22H17N3O
CP-465022 chemical structure, C26H24ClFN4O, CAS 199655-36-2
CP-465022
CAS 199655-36-2C26H24ClFN4O
CP 465022 Hydrochloride chemical structure, C26H25Cl2FN4O, CAS 1785666-59-2
CP 465022 Hydrochloride
CAS 1785666-59-2C26H25Cl2FN4O
Cp-465022 maleate chemical structure, C30H28ClFN4O5, CAS 199656-46-7
Cp-465022 maleate
CAS 199656-46-7C30H28ClFN4O5