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Murcko scaffold

Ring system with 4 rings and 25 atoms

13 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
13
With full pages
2
Scaffold SMILES

O=c1c2ccccc2nc(-c2ccccc2)n1N=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c2ccccc2nc(-c2ccccc2)n1N=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

2-(2-Chlorophenyl)-3-(((5-ethoxy-6-oxocyclohexa-2,4-dien-1-ylidene)methyl)amino)quinazolin-4(3H)-one chemical structure, C23H18ClN3O3, CAS 907166-59-0
2-(2-Chlorophenyl)-3-(((5-ethoxy-6-oxocyclohexa-2,4-dien-1-ylidene)methyl)amino)quinazolin-4(3H)-one
CAS 907166-59-0C23H18ClN3O3
3-[(4-Methoxybenzylidene)amino]-2-(4-methoxyphenyl)-4(3H)-quinazolinone chemical structure, C23H19N3O3, CAS 139722-36-4
3-[(4-Methoxybenzylidene)amino]-2-(4-methoxyphenyl)-4(3H)-quinazolinone
CAS 139722-36-4C23H19N3O3
3-[(3-Methoxybenzylidene)amino]-2-(3-methoxyphenyl)-4(3H)-quinazolinone chemical structure, C23H19N3O3, CAS 342390-30-1
3-[(3-Methoxybenzylidene)amino]-2-(3-methoxyphenyl)-4(3H)-quinazolinone
CAS 342390-30-1C23H19N3O3
3-[(2-Methoxybenzylidene)amino]-2-(2-methoxyphenyl)-4(3H)-quinazolinone chemical structure, C23H19N3O3, CAS 333778-48-6
3-[(2-Methoxybenzylidene)amino]-2-(2-methoxyphenyl)-4(3H)-quinazolinone
CAS 333778-48-6C23H19N3O3
3-{[(E)-(4-Nitrophenyl)methylidene]amino}-2-phenylquinazolin-4(3H)-one chemical structure, C21H14N4O3, CAS 56158-76-0
3-{[(E)-(4-Nitrophenyl)methylidene]amino}-2-phenylquinazolin-4(3H)-one
CAS 56158-76-0C21H14N4O3
3-((2-Chlorobenzylidene)amino)-2-phenyl-4(3H)-quinazolinone chemical structure, C21H14ClN3O, CAS 73861-03-7
3-((2-Chlorobenzylidene)amino)-2-phenyl-4(3H)-quinazolinone
CAS 73861-03-7C21H14ClN3O
3-[(E)-Benzylideneamino]-2-(4-methylphenyl)quinazolin-4-one chemical structure, C22H17N3O, CAS 63002-85-7
3-[(E)-Benzylideneamino]-2-(4-methylphenyl)quinazolin-4-one
CAS 63002-85-7C22H17N3O
4(3H)-Quinazolinone, 3-(((4-methoxyphenyl)methylene)amino)-2-phenyl- chemical structure, C22H17N3O2, CAS 73861-04-8
4(3H)-Quinazolinone, 3-(((4-methoxyphenyl)methylene)amino)-2-phenyl-
CAS 73861-04-8C22H17N3O2
3-[(3-Iodobenzylidene)amino]-2-(3-iodophenyl)-4(3H)-quinazolinone chemical structure, C21H13I2N3O, CAS 342390-31-2
3-[(3-Iodobenzylidene)amino]-2-(3-iodophenyl)-4(3H)-quinazolinone
CAS 342390-31-2C21H13I2N3O
N'-(4-Oxo-2-phenylquinazolin-3(4H)-yl)benzenecarboximidamide chemical structure, C21H16N4O, CAS 61330-42-5
N'-(4-Oxo-2-phenylquinazolin-3(4H)-yl)benzenecarboximidamide
CAS 61330-42-5C21H16N4O
3-[(E)-(2-Hydroxyphenyl)methylideneamino]-2-(4-methylphenyl)quinazolin-4-one chemical structure, C22H17N3O2, CAS 63002-87-9
3-[(E)-(2-Hydroxyphenyl)methylideneamino]-2-(4-methylphenyl)quinazolin-4-one
CAS 63002-87-9C22H17N3O2
2-(4-Methylphenyl)-3-[(4-oxocyclohexa-2,5-dien-1-ylidene)methylamino]quinazolin-4-one chemical structure, C22H17N3O2, CAS 63002-88-0
2-(4-Methylphenyl)-3-[(4-oxocyclohexa-2,5-dien-1-ylidene)methylamino]quinazolin-4-one
CAS 63002-88-0C22H17N3O2
3-{[(E)-(2-Hydroxyphenyl)methylidene]amino}-2-phenyl-4(3H)-quinazolinone chemical structure, C21H15N3O2, CAS 73861-06-0
3-{[(E)-(2-Hydroxyphenyl)methylidene]amino}-2-phenyl-4(3H)-quinazolinone
CAS 73861-06-0C21H15N3O2