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Murcko scaffold

Ring system with 4 rings and 26 atoms

7 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
7
With full pages
1
Scaffold SMILES

O=C(Nn1c(-c2ccccc2)nc2ccccc2c1=O)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nn1c(-c2ccccc2)nc2ccccc2c1=O)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

N-(4-Oxo-2-phenyl-quinazolin-3-yl)-4-(sulfanylmethyl)benzamide chemical structure, C22H17N3O2S, CAS 499-10-5
N-(4-Oxo-2-phenyl-quinazolin-3-yl)-4-(sulfanylmethyl)benzamide
CAS 499-10-5C22H17N3O2S
4-Nitro-N-(4-oxo-2-phenylquinazolin-3(4H)-yl)benzamide chemical structure, C21H14N4O4, CAS 178884-51-0
4-Nitro-N-(4-oxo-2-phenylquinazolin-3(4H)-yl)benzamide
CAS 178884-51-0C21H14N4O4
4-Methyl-N-(4-oxo-2-phenylquinazolin-3-yl)benzamide chemical structure, C22H17N3O2, CAS 178919-68-1
4-Methyl-N-(4-oxo-2-phenylquinazolin-3-yl)benzamide
CAS 178919-68-1C22H17N3O2
4-Chloro-N-[2-(3-methoxyphenyl)-4-oxoquinazolin-3-yl]benzamide chemical structure, C22H16ClN3O3, CAS 312698-77-4
4-Chloro-N-[2-(3-methoxyphenyl)-4-oxoquinazolin-3-yl]benzamide
CAS 312698-77-4C22H16ClN3O3
3-Methoxy-N-[2-(4-methylphenyl)-4-oxoquinazolin-3(4H)-yl]benzamide chemical structure, C23H19N3O3, CAS 488136-33-0
3-Methoxy-N-[2-(4-methylphenyl)-4-oxoquinazolin-3(4H)-yl]benzamide
CAS 488136-33-0C23H19N3O3
N-[2-(4-Bromophenyl)-4-oxoquinazolin-3(4H)-yl]-3,4-dimethoxybenzamide chemical structure, C23H18BrN3O4, CAS 388108-35-8
N-[2-(4-Bromophenyl)-4-oxoquinazolin-3(4H)-yl]-3,4-dimethoxybenzamide
CAS 388108-35-8C23H18BrN3O4
3-Chloro-N-[2-(3-chlorophenyl)-4-oxoquinazolin-3(4H)-yl]benzamide chemical structure, C21H13Cl2N3O2, CAS 388109-27-1
3-Chloro-N-[2-(3-chlorophenyl)-4-oxoquinazolin-3(4H)-yl]benzamide
CAS 388109-27-1C21H13Cl2N3O2