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Murcko scaffold

Ring system with 3 rings and 19 atoms

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
7
With full pages
3
Scaffold SMILES

c1ccc(Nc2ccnc(-c3ccccn3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Nc2ccnc(-c3ccccn3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

5-Methoxy-N-methyl-N-phenyl-2-(2-pyridinyl)-4-pyrimidinamine chemical structure, C17H16N4O, CAS 338771-63-4
5-Methoxy-N-methyl-N-phenyl-2-(2-pyridinyl)-4-pyrimidinamine
CAS 338771-63-4C17H16N4O
N-Phenyl-2-(2-pyridinyl)-6-(trifluoromethyl)-4-pyrimidinamine chemical structure, C16H11F3N4, CAS 338754-31-7
N-Phenyl-2-(2-pyridinyl)-6-(trifluoromethyl)-4-pyrimidinamine
CAS 338754-31-7C16H11F3N4
N-Methyl-6-(methylsulfanylmethyl)-N-phenyl-2-pyridin-2-ylpyrimidin-4-amine chemical structure, C18H18N4S, CAS 478031-24-2
N-Methyl-6-(methylsulfanylmethyl)-N-phenyl-2-pyridin-2-ylpyrimidin-4-amine
CAS 478031-24-2C18H18N4S
Phenol, 3-[[2-(2-pyridinyl)-6-(trifluoromethyl)-4-pyrimidinyl]amino]- chemical structure, C16H11F3N4O, CAS 744191-67-1
Phenol, 3-[[2-(2-pyridinyl)-6-(trifluoromethyl)-4-pyrimidinyl]amino]-
CAS 744191-67-1C16H11F3N4O
N-(2,4-Dimethoxyphenyl)-6-methyl-2-(pyridin-2-yl)pyrimidin-4-amine chemical structure, C18H18N4O2, CAS 750564-48-8
N-(2,4-Dimethoxyphenyl)-6-methyl-2-(pyridin-2-yl)pyrimidin-4-amine
CAS 750564-48-8C18H18N4O2
N-(3,5-Dimethoxyphenyl)-6-methyl-2-(pyridin-2-yl)pyrimidin-4-amine chemical structure, C18H18N4O2, CAS 787542-15-8
N-(3,5-Dimethoxyphenyl)-6-methyl-2-(pyridin-2-yl)pyrimidin-4-amine
CAS 787542-15-8C18H18N4O2
2-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-6-methyl-N-phenyl-4-pyrimidinamine chemical structure, C17H12ClF3N4, CAS 1357147-49-9
2-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-6-methyl-N-phenyl-4-pyrimidinamine
CAS 1357147-49-9C17H12ClF3N4