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Murcko scaffold

1,8-Diazaspiro[4.5]decane scaffold

108 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
108
With full pages
11
Scaffold SMILES

C1CNC2(C1)CCNCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,8-Diazaspiro[4.5]decane page
Murcko scaffold C1CNC2(C1)CCNCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 108 chemicals

1,8-Diazaspiro[4.5]decane chemical structure, C8H16N2, CAS 36142-00-4
1,8-Diazaspiro[4.5]decane
CAS 36142-00-4C8H16N2
tert-Butyl 1,8-diazaspiro(4.5)decane-8-carboxylate chemical structure, C13H24N2O2, CAS 937729-06-1
tert-Butyl 1,8-diazaspiro(4.5)decane-8-carboxylate
CAS 937729-06-1C13H24N2O2
tert-Butyl 1,8-diazaspiro(4.5)decane-1-carboxylate chemical structure, C13H24N2O2, CAS 885279-92-5
tert-Butyl 1,8-diazaspiro(4.5)decane-1-carboxylate
CAS 885279-92-5C13H24N2O2
1-Methyl-1,8-diazaspiro[4.5]decane chemical structure, C9H18N2, CAS 1158750-28-7
1-Methyl-1,8-diazaspiro[4.5]decane
CAS 1158750-28-7C9H18N2
1,8-Diazaspiro[4.5]decane dihydrochloride chemical structure, C8H18Cl2N2, CAS 1159822-20-4
1,8-Diazaspiro[4.5]decane dihydrochloride
CAS 1159822-20-4C8H18Cl2N2
8-Methyl-1,8-diazaspiro(4.5)decane chemical structure, C9H18N2, CAS 1153767-99-7
8-Methyl-1,8-diazaspiro(4.5)decane
CAS 1153767-99-7C9H18N2
n-Ethyl-1,8-diazaspiro[4.5]decane-1-carboxamide chemical structure, C11H21N3O, CAS 1057327-10-2
n-Ethyl-1,8-diazaspiro[4.5]decane-1-carboxamide
CAS 1057327-10-2C11H21N3O
1,8-Diazaspiro[4.5]decane-1-carboxylic acid, 1,1-dimethylethyl ester, ethanedioate (1:1) chemical structure, C15H26N2O6, CAS 959841-74-8
1,8-Diazaspiro[4.5]decane-1-carboxylic acid, 1,1-dimethylethyl ester, ethanedioate (1:1)
CAS 959841-74-8C15H26N2O6
tert-Butyl 2-(trifluoromethyl)-1,8-diazaspiro[4.5]decane-8-carboxylate chemical structure, C14H23F3N2O2, CAS 1251020-85-5
tert-Butyl 2-(trifluoromethyl)-1,8-diazaspiro[4.5]decane-8-carboxylate
CAS 1251020-85-5C14H23F3N2O2
1-Methyl-1,8-diazaspiro[4.5]decane dihydrochloride chemical structure, C9H20Cl2N2, CAS 1432679-85-0
1-Methyl-1,8-diazaspiro[4.5]decane dihydrochloride
CAS 1432679-85-0C9H20Cl2N2
8-Boc-1,8-diazaspiro[4.5]decane oxalate chemical structure, C15H26N2O6, CAS 1408075-17-1
8-Boc-1,8-diazaspiro[4.5]decane oxalate
CAS 1408075-17-1C15H26N2O6
tert-Butyl 1,8-diazaspiro[4.5]decane-1-carboxylate hydrochloride chemical structure, C13H25ClN2O2, CAS 1153767-91-9
tert-Butyl 1,8-diazaspiro[4.5]decane-1-carboxylate hydrochloride
CAS 1153767-91-9C13H25ClN2O2
1-(1,8-Diazaspiro[4.5]decan-8-yl)ethanone chemical structure, C10H18N2O, CAS 1422065-07-3
1-(1,8-Diazaspiro[4.5]decan-8-yl)ethanone
CAS 1422065-07-3C10H18N2O
1-(1,8-Diazaspiro[4.5]decan-1-yl)ethan-1-one chemical structure, C10H18N2O, CAS 1784089-80-0
1-(1,8-Diazaspiro[4.5]decan-1-yl)ethan-1-one
CAS 1784089-80-0C10H18N2O
1-Propyl-1,8-diazaspiro[4.5]decane chemical structure, C11H22N2, CAS 1782043-09-7
1-Propyl-1,8-diazaspiro[4.5]decane
CAS 1782043-09-7C11H22N2
1-Ethyl-1,8-diazaspiro[4.5]decane chemical structure, C10H20N2, CAS 1784090-05-6
1-Ethyl-1,8-diazaspiro[4.5]decane
CAS 1784090-05-6C10H20N2
1-(2-Methylpropyl)-1,8-diazaspiro[4.5]decane chemical structure, C12H24N2, CAS 1781868-00-5
1-(2-Methylpropyl)-1,8-diazaspiro[4.5]decane
CAS 1781868-00-5C12H24N2
1-(Propan-2-yl)-1,8-diazaspiro[4.5]decane chemical structure, C11H22N2, CAS 1781563-66-3
1-(Propan-2-yl)-1,8-diazaspiro[4.5]decane
CAS 1781563-66-3C11H22N2
1,8-Dimethyl-1,8-diazaspiro[4.5]decan-4-amine chemical structure, C10H21N3, CAS 1544376-10-4
1,8-Dimethyl-1,8-diazaspiro[4.5]decan-4-amine
CAS 1544376-10-4C10H21N3
1-Methyl-1,8-diazaspiro[4.5]decan-4-ol chemical structure, C9H18N2O, CAS 1543789-76-9
1-Methyl-1,8-diazaspiro[4.5]decan-4-ol
CAS 1543789-76-9C9H18N2O
N,N-Dimethyl-1,8-diazaspiro[4.5]decane-1-carboxamide chemical structure, C11H21N3O, CAS 2091232-31-2
N,N-Dimethyl-1,8-diazaspiro[4.5]decane-1-carboxamide
CAS 2091232-31-2C11H21N3O
8-(Methylsulfonyl)-1,8-diazaspiro[4.5]decane chemical structure, C9H18N2O2S, CAS 1422062-53-0
8-(Methylsulfonyl)-1,8-diazaspiro[4.5]decane
CAS 1422062-53-0C9H18N2O2S
tert-Butyl 1,8-diazaspiro[4.5]decane-8-carboxylate hydrochloride chemical structure, C13H25ClN2O2, CAS 1890715-57-7
tert-Butyl 1,8-diazaspiro[4.5]decane-8-carboxylate hydrochloride
CAS 1890715-57-7C13H25ClN2O2
tert-Butyl 1,8-diazaspiro[4.5]decane-8-carboxylate hemioxalate chemical structure, C28H50N4O8, CAS 1523618-36-1
tert-Butyl 1,8-diazaspiro[4.5]decane-8-carboxylate hemioxalate
CAS 1523618-36-1C28H50N4O8