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Murcko scaffold

8-Oxa-2-azaspiro(4.5)decane scaffold

140 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
140
With full pages
18
Scaffold SMILES

C1CC2(CCOCC2)CN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 8-Oxa-2-azaspiro(4.5)decane page
Murcko scaffold C1CC2(CCOCC2)CN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 140 chemicals

2-Isobutyl-8-oxa-2-azaspiro[4.5]decane-4-carboxylic acid chemical structure, C13H23NO3, CAS 939761-67-8
2-Isobutyl-8-oxa-2-azaspiro[4.5]decane-4-carboxylic acid
CAS 939761-67-8C13H23NO3
8-Oxa-2-azaspiro(4.5)decane chemical structure, C8H15NO, CAS 310-93-0
8-Oxa-2-azaspiro(4.5)decane
CAS 310-93-0C8H15NO
2-Isopropyl-8-oxa-2-aza-spiro[4.5]decane-4-carboxylic acid hydrochloride chemical structure, C12H22ClNO3, CAS 939761-64-5
2-Isopropyl-8-oxa-2-aza-spiro[4.5]decane-4-carboxylic acid hydrochloride
CAS 939761-64-5C12H22ClNO3
8-Oxa-2-azaspiro(4.5)decane hydrochloride chemical structure, C8H16ClNO, CAS 1408074-48-5
8-Oxa-2-azaspiro(4.5)decane hydrochloride
CAS 1408074-48-5C8H16ClNO
Ethyl 8-oxa-2-azaspiro[4.5]decane-3-carboxylate chemical structure, C11H19NO3, CAS 1399843-71-0
Ethyl 8-oxa-2-azaspiro[4.5]decane-3-carboxylate
CAS 1399843-71-0C11H19NO3
2-Isopropyl-8-oxa-2-azaspiro[4.5]decane chemical structure, C11H21NO, CAS 1420969-55-6
2-Isopropyl-8-oxa-2-azaspiro[4.5]decane
CAS 1420969-55-6C11H21NO
1-Methyl-8-oxa-2-azaspiro[4.5]decane chemical structure, C9H17NO, CAS 1250678-54-6
1-Methyl-8-oxa-2-azaspiro[4.5]decane
CAS 1250678-54-6C9H17NO
8-Oxa-2-azaspiro[4.5]decane-4-carboxylic acid chemical structure, C9H15NO3, CAS 1339071-65-6
8-Oxa-2-azaspiro[4.5]decane-4-carboxylic acid
CAS 1339071-65-6C9H15NO3
7-Ethyl-8-oxa-2-azaspiro[4.5]decane chemical structure, C10H19NO, CAS 1341600-03-0
7-Ethyl-8-oxa-2-azaspiro[4.5]decane
CAS 1341600-03-0C10H19NO
7-Methyl-8-oxa-2-azaspiro[4.5]decane chemical structure, C9H17NO, CAS 1344371-39-6
7-Methyl-8-oxa-2-azaspiro[4.5]decane
CAS 1344371-39-6C9H17NO
7,7-Dimethyl-8-oxa-2-azaspiro(4.5)decane chemical structure, C10H19NO, CAS 1341711-94-1
7,7-Dimethyl-8-oxa-2-azaspiro(4.5)decane
CAS 1341711-94-1C10H19NO
8-Oxa-2-azaspiro[4.5]decane-2-carboxylic acid chemical structure, C9H15NO3, CAS 1420887-92-8
8-Oxa-2-azaspiro[4.5]decane-2-carboxylic acid
CAS 1420887-92-8C9H15NO3
2-((tert-Butoxy)carbonyl)-8-oxa-2-azaspiro(4.5)decane-4-carboxylic acid chemical structure, C14H23NO5, CAS 1251021-24-5
2-((tert-Butoxy)carbonyl)-8-oxa-2-azaspiro(4.5)decane-4-carboxylic acid
CAS 1251021-24-5C14H23NO5
tert-Butyl 8-oxa-2-azaspiro[4.5]decane-2-carboxylate chemical structure, C13H23NO3, CAS 1420804-30-3
tert-Butyl 8-oxa-2-azaspiro[4.5]decane-2-carboxylate
CAS 1420804-30-3C13H23NO3
2-Amino-3-methyl-1-(8-oxa-2-azaspiro[4.5]decan-2-yl)butan-1-one chemical structure, C13H24N2O2, CAS 1420785-52-9
2-Amino-3-methyl-1-(8-oxa-2-azaspiro[4.5]decan-2-yl)butan-1-one
CAS 1420785-52-9C13H24N2O2
2-Amino-1-(8-oxa-2-azaspiro[4.5]decan-2-yl)propan-1-one chemical structure, C11H20N2O2, CAS 1420798-00-0
2-Amino-1-(8-oxa-2-azaspiro[4.5]decan-2-yl)propan-1-one
CAS 1420798-00-0C11H20N2O2
2-Ethyl-8-oxa-2-azaspiro[4.5]decane chemical structure, C10H19NO, CAS 1420835-62-6
2-Ethyl-8-oxa-2-azaspiro[4.5]decane
CAS 1420835-62-6C10H19NO
2-Chloro-1-(8-oxa-2-azaspiro[4.5]decan-2-yl)ethanone chemical structure, C10H16ClNO2, CAS 1420835-73-9
2-Chloro-1-(8-oxa-2-azaspiro[4.5]decan-2-yl)ethanone
CAS 1420835-73-9C10H16ClNO2
2-(2-Chloroethyl)-8-oxa-2-azaspiro[4.5]decane chemical structure, C10H18ClNO, CAS 1420969-65-8
2-(2-Chloroethyl)-8-oxa-2-azaspiro[4.5]decane
CAS 1420969-65-8C10H18ClNO
2-Methyl-8-oxa-2-azaspiro[4.5]decane chemical structure, C9H17NO, CAS 1420980-09-1
2-Methyl-8-oxa-2-azaspiro[4.5]decane
CAS 1420980-09-1C9H17NO
2-Amino-1-(8-oxa-2-azaspiro[4.5]decan-2-yl)ethanone chemical structure, C10H18N2O2, CAS 1420958-15-1
2-Amino-1-(8-oxa-2-azaspiro[4.5]decan-2-yl)ethanone
CAS 1420958-15-1C10H18N2O2
2-(8-Oxa-2-azaspiro[4.5]decan-2-yl)ethanamine chemical structure, C10H20N2O, CAS 1420969-72-7
2-(8-Oxa-2-azaspiro[4.5]decan-2-yl)ethanamine
CAS 1420969-72-7C10H20N2O
2-(8-Oxa-2-azaspiro[4.5]decan-2-yl)acetic acid chemical structure, C10H17NO3, CAS 1420848-66-3
2-(8-Oxa-2-azaspiro[4.5]decan-2-yl)acetic acid
CAS 1420848-66-3C10H17NO3
8-Oxa-2-azaspiro[4.5]decane oxalate chemical structure, C10H17NO5, CAS 1408075-68-2
8-Oxa-2-azaspiro[4.5]decane oxalate
CAS 1408075-68-2C10H17NO5