Murcko scaffold
Spiro(4.5)decane scaffold
241 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 10
- Chemicals
- 241
- With full pages
- 18
Scaffold SMILES
C1CCC2(CC1)CCCC2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 241 chemicals
Spiro(4.5)decane
CAS 176-63-6C10H18
![Spiro[4.5]decane, 7-hexadecyl- chemical structure, C26H50, CAS 2307-06-4](/s/BNDDTWKJQMCKBA-UHFFFAOYSA-N.svg)
Spiro[4.5]decane, 7-hexadecyl-
CAS 2307-06-4C26H50
Spiro(4.5)decan-1-ol
CAS 17347-63-6C10H18O
Lubimin
CAS 35951-50-9C15H24O2
![6-Methylspiro[4.5]decan-6-ol chemical structure, C11H20O, CAS 14551-31-6](/s/FMWYGDCRQTUHJN-UHFFFAOYSA-N.svg)
6-Methylspiro[4.5]decan-6-ol
CAS 14551-31-6C11H20O
Lubiminol
CAS 55784-92-4C15H26O2
Spiro(4.5)decane-6-carbaldehyde
CAS 76713-59-2C11H18O
![(6-Hydroxyspiro[4.5]decan-6-yl)acetic acid chemical structure, C12H20O3, CAS 89789-37-7](/s/TWWLUXUQTYXWCJ-UHFFFAOYSA-N.svg)
(6-Hydroxyspiro[4.5]decan-6-yl)acetic acid
CAS 89789-37-7C12H20O3
![Spiro[4.5]decane-2-carboxylic acid chemical structure, C11H18O2, CAS 18244-50-3](/s/NTGFSUIRCGHSQM-UHFFFAOYSA-N.svg)
Spiro[4.5]decane-2-carboxylic acid
CAS 18244-50-3C11H18O2
![Spiro[4.5]decane-8-carboxylic acid chemical structure, C11H18O2, CAS 19027-23-7](/s/NOHIIJZANZJPGI-UHFFFAOYSA-N.svg)
Spiro[4.5]decane-8-carboxylic acid
CAS 19027-23-7C11H18O2
Epioxylubimin
CAS 69350-60-3C15H24O3
![Spiro[4.5]decan-6-amine chemical structure, C10H19N, CAS 20440-70-4](/s/KUODKTLZDFOEOB-UHFFFAOYSA-N.svg)
Spiro[4.5]decan-6-amine
CAS 20440-70-4C10H19N
![Spiro[4.5]decan-2-ol chemical structure, C10H18O, CAS 173202-21-6](/s/DDIJOSWBLDJNPH-UHFFFAOYSA-N.svg)
Spiro[4.5]decan-2-ol
CAS 173202-21-6C10H18O
![1,8-Dimethyl-4-(propan-2-yl)spiro[4.5]decane chemical structure, C15H28, CAS 20479-49-6](/s/UXUIXVKLBWVGHM-UHFFFAOYSA-N.svg)
1,8-Dimethyl-4-(propan-2-yl)spiro[4.5]decane
CAS 20479-49-6C15H28
![6,10-Dimethyl-2-(propan-2-yl)spiro[4.5]decane chemical structure, C15H28, CAS 70223-27-7](/s/HFHBKDQLMMKJAY-UHFFFAOYSA-N.svg)
6,10-Dimethyl-2-(propan-2-yl)spiro[4.5]decane
CAS 70223-27-7C15H28
![Spiro[4.5]decane-1-carboxylic acid chemical structure, C11H18O2, CAS 1558373-03-7](/s/WZCCMMFDZFPIDM-UHFFFAOYSA-N.svg)
Spiro[4.5]decane-1-carboxylic acid
CAS 1558373-03-7C11H18O2
![Spiro[4.5]decan-1-amine chemical structure, C10H19N, CAS 27992-29-6](/s/NKBQOEBTDKIYHY-UHFFFAOYSA-N.svg)
Spiro[4.5]decan-1-amine
CAS 27992-29-6C10H19N
![Spiro[4.5]decan-2-amine hydrochloride chemical structure, C10H20ClN, CAS 2126-95-6](/s/IIWNREGSSWKYII-UHFFFAOYSA-N.svg)
Spiro[4.5]decan-2-amine hydrochloride
CAS 2126-95-6C10H20ClN
![Spiro[4.5]decan-2-amine chemical structure, C10H19N, CAS 3643-27-4](/s/UXVFDIXOVKPEDC-UHFFFAOYSA-N.svg)
Spiro[4.5]decan-2-amine
CAS 3643-27-4C10H19N
![Spiro[4.5]decan-7-amine chemical structure, C10H19N, CAS 782394-98-3](/s/HTYGULHVQWFVBL-UHFFFAOYSA-N.svg)
Spiro[4.5]decan-7-amine
CAS 782394-98-3C10H19N
Spiro(4.5)decan-7-amine hydrochloride
CAS 62439-56-9C10H20ClN
![Spiro[4.5]decan-8-amine hydrochloride chemical structure, C10H20ClN, CAS 3643-12-7](/s/MKWWYRMCMDCHNO-UHFFFAOYSA-N.svg)
Spiro[4.5]decan-8-amine hydrochloride
CAS 3643-12-7C10H20ClN
![Spiro[4.5]decan-8-amine chemical structure, C10H19N, CAS 3643-25-2](/s/QPIGFMXNPDOLDK-UHFFFAOYSA-N.svg)
Spiro[4.5]decan-8-amine
CAS 3643-25-2C10H19N
Hydroxylubimin
CAS 55784-90-2C15H24O3
- (2R,5S,6R,8S,10R)-8-Hydroxy-10-methyl-2-(1-methylethenyl)spiro(4.5)decane-6-carboxaldehyde64024-09-5C15H24O2
- 10-Epilubiminol64024-11-9C15H26O2
- (1S,4R)-1,4-Dimethylspiro[4.5]decane53881-15-5C12H22
- 15-Dihydroepioxylubimin129214-59-1C15H26O3
- Spiro(4.5)decan-8-ol1266120-78-8C10H18O
- 8-Hydroxy-spiro[4.5]decane-8-carbonitrile1147731-80-3C11H17NO
- Spiro[4.5]dec-8-yl-methanol1082373-83-8C11H20O
- Spiro[4.5]decane-8-carbaldehyde1594790-00-7C11H18O
- Methyl 6-aminospiro[4.5]decane-7-carboxylate1383446-44-3C12H21NO2
- Spiro[4.5]decane-9-carboxylic acid1504790-36-6C11H18O2
- (1-Hydroxyspiro[4.5]decan-1-yl)acetic acid89789-36-6C12H20O3
- Spiro[4.5]decane-6-carbonitrile141632-78-2C11H17N
- 1,8-Dimethyl-4-(propan-2-yl)spiro[4.5]decan-7-ol39510-27-5C15H28O
- 15-Norepilubiminol349106-30-5C14H24O2
- 15-Norlubiminol349106-29-2C14H24O2
- 9-Aminospiro[4.5]decan-6-ol1502556-23-1C10H19NO
- 2-(Spiro(4.5)decan-8-yl)acetic acid1517177-38-6C12H20O2
- {Spiro[4.5]decan-8-yl}methanamine1082373-86-1C11H21N
- 1-{Spiro[4.5]decan-1-yl}methanamine1554317-16-6C11H21N
- N-Methylspiro[4.5]decan-8-amine1545390-29-1C11H21N
- 2-{Spiro[4.5]decan-8-yl}ethan-1-amine1557697-16-1C12H23N
- 2-{Spiro[4.5]decan-1-yl}ethan-1-amine1554342-24-3C12H23N
- Spiro(4.5)decane-6-carboxylic acid37457-41-3C11H18O2
- 2-{Spiro[4.5]decan-8-yl}propanoic acid1547045-66-8C13H22O2
Related scaffolds
Same ring framework with different atoms or bond orders
C1CCC2(CC1)OCCO258 chemicals
O=C1NC(=O)C2(CCCCC2)N145 chemicals
C1CCC2(C1)CCNCC221 chemicals
C1COC2(C1)CCNCC219 chemicals
C1CC2(CCOCC2)CN118 chemicals
C1CCC2(CC1)CCNC218 chemicals
C1CC2(CCN1)CCOC215 chemicals
C1CC2(CCN1)CCNC213 chemicals
C1CNC2(C1)CCNCC211 chemicals
C1CNC2(C1)CCOCC211 chemicals
C1CCC2(CC1)NCCO210 chemicals
C1CCC2(CC1)CCCO210 chemicals