Murcko scaffold
RefChem:357139 scaffold
49 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 21
- Chemicals
- 49
- With full pages
- 4
Scaffold SMILES
O=C(Nc1cccc2ccccc12)OCc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 49 chemicals
RefChem:357139
CAS 6336-03-4C18H15NO2
1-Phenylethyl N-naphthalen-1-ylcarbamate
CAS 119994-28-4C19H17NO2
![5-{[(Benzyloxy)carbonyl]amino}naphthalene-1-sulfonic acid chemical structure, C18H15NO5S, CAS 779295-89-5](/s/HUTHENQYLLNLMP-UHFFFAOYSA-N.svg)
5-{[(Benzyloxy)carbonyl]amino}naphthalene-1-sulfonic acid
CAS 779295-89-5C18H15NO5S
![4-{[(Benzyloxy)carbonyl]amino}naphthalene-1-sulfonic acid chemical structure, C18H15NO5S, CAS 848641-11-2](/s/HYNQKYQUNOZNTK-UHFFFAOYSA-N.svg)
4-{[(Benzyloxy)carbonyl]amino}naphthalene-1-sulfonic acid
CAS 848641-11-2C18H15NO5S
5-(N-Benzyloxycarbonylamino)-1-naphthalenesulphonyl chloride
CAS 119834-89-8C18H14ClNO4S
![4-{[(Benzyloxy)carbonyl]amino}naphthalene-1-carboxylic acid chemical structure, C19H15NO4, CAS 95092-75-4](/s/WSKDOFYHWRAHIC-UHFFFAOYSA-N.svg)
4-{[(Benzyloxy)carbonyl]amino}naphthalene-1-carboxylic acid
CAS 95092-75-4C19H15NO4
Benzyl N-(4-hydroxynaphthalen-1-yl)carbamate
CAS 1394945-83-5C18H15NO3
Benzyl (4-bromonaphthalen-1-yl)carbamate
CAS 1215206-51-1C18H14BrNO2
Jhdm-IN-1
CAS 1310809-17-6C27H29N3O6
Methylstat
CAS 1310877-95-2C28H31N3O6
(1S)-1-Phenylpropyl N-(naphthalen-1-yl)carbamate
CAS 120055-56-3C20H19NO2
Benzyl (7-cyano-3-formylnaphthalen-1-yl)carbamate
CAS 823236-23-3C20H14N2O3
Benzyl N-(5-hydroxynaphthalen-1-yl)carbamate
CAS 1871388-04-3C18H15NO3
Benzyl N-(7-hydroxynaphthalen-1-yl)carbamate
CAS 2222768-48-9C18H15NO3
![4-{[(Benzyloxy)carbonyl]amino}naphthalene-2-carboxylic acid chemical structure, C19H15NO4, CAS 2137634-42-3](/s/GLZJUKHPGDILSV-UHFFFAOYSA-N.svg)
4-{[(Benzyloxy)carbonyl]amino}naphthalene-2-carboxylic acid
CAS 2137634-42-3C19H15NO4
![5-{[(Benzyloxy)carbonyl]amino}naphthalene-2-carboxylic acid chemical structure, C19H15NO4, CAS 2171806-76-9](/s/RYZNHEBXEJZVRG-UHFFFAOYSA-N.svg)
5-{[(Benzyloxy)carbonyl]amino}naphthalene-2-carboxylic acid
CAS 2171806-76-9C19H15NO4
![5-{[(Benzyloxy)carbonyl]amino}naphthalene-1-carboxylic acid chemical structure, C19H15NO4, CAS 2580239-60-5](/s/AGTBKHMLHAVFCA-UHFFFAOYSA-N.svg)
5-{[(Benzyloxy)carbonyl]amino}naphthalene-1-carboxylic acid
CAS 2580239-60-5C19H15NO4
![1-{[(Benzyloxy)carbonyl]amino}-4-bromonaphthalene-2-carboxylic acid chemical structure, C19H14BrNO4, CAS 2580249-06-3](/s/AMVOBFGBSFJKMH-UHFFFAOYSA-N.svg)
1-{[(Benzyloxy)carbonyl]amino}-4-bromonaphthalene-2-carboxylic acid
CAS 2580249-06-3C19H14BrNO4
![2-[(4-{[(Benzyloxy)carbonyl]amino}naphthalen-1-yl)oxy]acetic acid chemical structure, C20H17NO5, CAS 2580185-10-8](/s/ZCVSXZYZNUUPKC-UHFFFAOYSA-N.svg)
2-[(4-{[(Benzyloxy)carbonyl]amino}naphthalen-1-yl)oxy]acetic acid
CAS 2580185-10-8C20H17NO5
![1-{[(Benzyloxy)carbonyl]amino}naphthalene-2-carboxylic acid chemical structure, C19H15NO4, CAS 2580189-05-3](/s/DOGGMQVQZCMUTK-UHFFFAOYSA-N.svg)
1-{[(Benzyloxy)carbonyl]amino}naphthalene-2-carboxylic acid
CAS 2580189-05-3C19H15NO4
![4-[(4-{[(Benzyloxy)carbonyl]amino}naphthalen-1-yl)oxy]butanoic acid chemical structure, C22H21NO5, CAS 2639421-99-9](/s/ADAJQXIZVDIUEW-UHFFFAOYSA-N.svg)
4-[(4-{[(Benzyloxy)carbonyl]amino}naphthalen-1-yl)oxy]butanoic acid
CAS 2639421-99-9C22H21NO5
Benzyl N-(3-bromonaphthalen-1-yl)carbamate
CAS 2680672-25-5C18H14BrNO2
Benzyl N-(4-cyano-7-hydroxynaphthalen-1-yl)carbamate
CAS 2680776-77-4C19H14N2O3
![5-{[(Benzyloxy)carbonyl]amino}naphthalene-2-sulfonic acid chemical structure, C18H15NO5S, CAS 2680701-97-5](/s/WAWFNMBLOQVPSB-UHFFFAOYSA-N.svg)
5-{[(Benzyloxy)carbonyl]amino}naphthalene-2-sulfonic acid
CAS 2680701-97-5C18H15NO5S
- Benzyl N-(4-bromo-2-methylnaphthalen-1-yl)carbamate2680745-64-4C19H16BrNO2
- Benzyl N-(3-chloro-4-hydroxynaphthalen-1-yl)carbamate2680884-79-9C18H14ClNO3
- Benzyl N-[4-(3-cyanopropoxy)naphthalen-1-yl]carbamate2680795-62-2C22H20N2O3
- 8-{[(Benzyloxy)carbonyl]amino}naphthalene-1-carboxylic acid2680673-12-3C19H15NO4
- Benzyl N-(4-hydroxy-3-methylnaphthalen-1-yl)carbamate2680775-67-9C19H17NO3
- Benzyl N-[2-(hydroxymethyl)naphthalen-1-yl]carbamate2680900-11-0C19H17NO3
- 4-{[(Benzyloxy)carbonyl]amino}-5-hydroxynaphthalene-2,7-disulfonic acid2680759-83-3C18H15NO9S2
- Benzyl N-[6-(fluorosulfonyl)naphthalen-1-yl]carbamate2680755-31-9C18H14FNO4S
- Benzyl N-(6-chloro-4-hydroxynaphthalen-1-yl)carbamate2680831-26-7C18H14ClNO3
- 8-{[(Benzyloxy)carbonyl]amino}naphthalene-1-sulfonic acid2680817-90-5C18H15NO5S
- 8-{[(Benzyloxy)carbonyl]amino}naphthalene-2-sulfonic acid2680784-72-7C18H15NO5S
- Benzyl N-(4-nitronaphthalen-1-yl)carbamate2680805-71-2C18H14N2O4
- Benzyl N-(4-bromo-2-cyanonaphthalen-1-yl)carbamate2680712-20-1C19H13BrN2O2
- Benzyl N-(8-hydroxynaphthalen-1-yl)carbamate2680892-76-4C18H15NO3
- Benzyl N-(4-iodonaphthalen-1-yl)carbamate2680806-67-9C18H14INO2
- Benzyl N-(7-sulfamoylnaphthalen-1-yl)carbamate2680898-81-9C18H16N2O4S
- Benzyl N-(2-cyanonaphthalen-1-yl)carbamate2680689-51-2C19H14N2O2
- Benzyl N-(naphthalen-1-yl)-N-(prop-2-yn-1-yl)carbamate2680681-89-2C21H17NO2
- Benzyl N-(5-bromonaphthalen-1-yl)carbamate2680701-20-4C18H14BrNO2
- Benzyl N-(8-bromonaphthalen-1-yl)carbamate2680796-19-2C18H14BrNO2
- Benzyl N-(4-hydroxy-3-methoxynaphthalen-1-yl)carbamate2680834-77-7C19H17NO4
- Benzyl N-(7-bromonaphthalen-1-yl)carbamate2680816-40-2C18H14BrNO2
- Benzyl N-(2-acetylnaphthalen-1-yl)carbamate2680671-85-4C20H17NO3
- 8-{[(Benzyloxy)carbonyl]amino}naphthalene-2-carboxylic acid2913424-79-8C19H15NO4
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold O=C(CSc1nc(=O)[nH]c2c1CCCC2)Nc1ccccc1](/scaffold/AJRIOXSLDWQDNT-UHFFFAOYSA-N/structure.svg)
O=C(CSc1nc(=O)[nH]c2c1CCCC2)Nc1ccccc117 chemicals
O=C(COc1cccc2c1CCNC2=O)Nc1ccccc111 chemicals![Scaffold O=C(CSc1ncnc2[nH]c(=O)[nH]c(=O)c12)Nc1ccccc1](/scaffold/NEPLTQYIBVZGDT-UHFFFAOYSA-N/structure.svg)
O=C(CSc1ncnc2[nH]c(=O)[nH]c(=O)c12)Nc1ccccc110 chemicals![Scaffold O=C(COc1cccc2c(=O)[nH]ccc12)Nc1ccccc1](/scaffold/KUKRKXYIWBTJFC-UHFFFAOYSA-N/structure.svg)
O=C(COc1cccc2c(=O)[nH]ccc12)Nc1ccccc19 chemicals
O=C(NNC(=O)c1cccc2ccccc12)c1ccccc19 chemicals
O=C(CSc1nncc2ccccc12)Nc1ccccc19 chemicals
O=C(NN=Cc1cccc2ccccc12)c1ccccc18 chemicals
O=C(COc1cccc2ccccc12)Nc1ccccc17 chemicals
O=C(COc1ccccc1)Nc1cccc2ccccc127 chemicals![Scaffold O=C(NNC(=O)c1n[nH]c(=O)c2ccccc12)c1ccccc1](/scaffold/IDQDJYQKVHYGRV-UHFFFAOYSA-N/structure.svg)
O=C(NNC(=O)c1n[nH]c(=O)c2ccccc12)c1ccccc17 chemicals
O=C1CN(C(=O)COC(=O)c2ccccc2)c2ccccc2N17 chemicals
O=C(COC(=O)c1ccnc2ccccc12)c1ccccc17 chemicals