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Murcko scaffold

Ring system with 3 rings and 21 atoms

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
16
With full pages
7
Scaffold SMILES

O=C(NC1CCCCC1)C1CC(=O)N(c2ccccc2)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NC1CCCCC1)C1CC(=O)N(c2ccccc2)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

1-(4-Bromophenyl)-N-cyclohexyl-5-oxopyrrolidine-3-carboxamide chemical structure, C17H21BrN2O2, CAS 333430-89-0
1-(4-Bromophenyl)-N-cyclohexyl-5-oxopyrrolidine-3-carboxamide
CAS 333430-89-0C17H21BrN2O2
N-Cyclohexyl-1-(3-nitrophenyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C17H21N3O4, CAS 331982-71-9
N-Cyclohexyl-1-(3-nitrophenyl)-5-oxopyrrolidine-3-carboxamide
CAS 331982-71-9C17H21N3O4
N-Cyclohexyl-1-(4-fluorophenyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C17H21FN2O2, CAS 331986-72-2
N-Cyclohexyl-1-(4-fluorophenyl)-5-oxopyrrolidine-3-carboxamide
CAS 331986-72-2C17H21FN2O2
1-(3-Chloro-2-methylphenyl)-N-cyclohexyl-5-oxopyrrolidine-3-carboxamide chemical structure, C18H23ClN2O2, CAS 404369-85-3
1-(3-Chloro-2-methylphenyl)-N-cyclohexyl-5-oxopyrrolidine-3-carboxamide
CAS 404369-85-3C18H23ClN2O2
1-(4-Chlorophenyl)-N-cyclohexyl-5-oxopyrrolidine-3-carboxamide chemical structure, C17H21ClN2O2, CAS 339218-65-4
1-(4-Chlorophenyl)-N-cyclohexyl-5-oxopyrrolidine-3-carboxamide
CAS 339218-65-4C17H21ClN2O2
N-Cyclohexyl-1-(4-ethoxyphenyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C19H26N2O3, CAS 364744-95-6
N-Cyclohexyl-1-(4-ethoxyphenyl)-5-oxopyrrolidine-3-carboxamide
CAS 364744-95-6C19H26N2O3
1-(3-Chloro-4-methylphenyl)-N-cyclohexyl-5-oxopyrrolidine-3-carboxamide chemical structure, C18H23ClN2O2, CAS 713081-23-3
1-(3-Chloro-4-methylphenyl)-N-cyclohexyl-5-oxopyrrolidine-3-carboxamide
CAS 713081-23-3C18H23ClN2O2
N-(4-Methylcyclohexyl)-1-(4-methylphenyl)-5-oxo-3-pyrrolidinecarboxamide chemical structure, C19H26N2O2, CAS 956790-23-1
N-(4-Methylcyclohexyl)-1-(4-methylphenyl)-5-oxo-3-pyrrolidinecarboxamide
CAS 956790-23-1C19H26N2O2
N-Cyclohexyl-1-(3-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C18H24N2O3, CAS 713081-64-2
N-Cyclohexyl-1-(3-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide
CAS 713081-64-2C18H24N2O3
1-(4-Methoxyphenyl)-N-(4-methylcyclohexyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C19H26N2O3, CAS 957507-51-6
1-(4-Methoxyphenyl)-N-(4-methylcyclohexyl)-5-oxopyrrolidine-3-carboxamide
CAS 957507-51-6C19H26N2O3
1-(4-Chlorophenyl)-N-(4-methylcyclohexyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C18H23ClN2O2, CAS 956201-73-3
1-(4-Chlorophenyl)-N-(4-methylcyclohexyl)-5-oxopyrrolidine-3-carboxamide
CAS 956201-73-3C18H23ClN2O2
N-Cyclohexyl-1-(4-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C18H24N2O3, CAS 364616-45-5
N-Cyclohexyl-1-(4-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide
CAS 364616-45-5C18H24N2O3
N-Cyclohexyl-1-(3,5-dimethylphenyl)-5-oxo-3-pyrrolidinecarboxamide chemical structure, C19H26N2O2, CAS 876716-21-1
N-Cyclohexyl-1-(3,5-dimethylphenyl)-5-oxo-3-pyrrolidinecarboxamide
CAS 876716-21-1C19H26N2O2
1-[4-(Acetylamino)phenyl]-N-cyclohexyl-5-oxopyrrolidine-3-carboxamide chemical structure, C19H25N3O3, CAS 905180-84-9
1-[4-(Acetylamino)phenyl]-N-cyclohexyl-5-oxopyrrolidine-3-carboxamide
CAS 905180-84-9C19H25N3O3
N-(1-Cyanocyclohexyl)-5-oxo-1-[3-(trifluoromethyl)phenyl]pyrrolidine-3-carboxamide chemical structure, C19H20F3N3O2, CAS 1424480-87-4
N-(1-Cyanocyclohexyl)-5-oxo-1-[3-(trifluoromethyl)phenyl]pyrrolidine-3-carboxamide
CAS 1424480-87-4C19H20F3N3O2
N-(4,4-Difluorocyclohexyl)-1-(4-fluorophenyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C17H19F3N2O2, CAS 2034461-56-6
N-(4,4-Difluorocyclohexyl)-1-(4-fluorophenyl)-5-oxopyrrolidine-3-carboxamide
CAS 2034461-56-6C17H19F3N2O2