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Murcko scaffold

Ring system with 2 rings and 16 atoms

19 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
19
With full pages
7
Scaffold SMILES

O=C(Cc1cccs1)NCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1cccs1)NCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

N-(2-Methoxybenzyl)-2-(thiophen-2-yl)acetamide chemical structure, C14H15NO2S, CAS 349088-05-7
N-(2-Methoxybenzyl)-2-(thiophen-2-yl)acetamide
CAS 349088-05-7C14H15NO2S
N-[(4-Methylphenyl)methyl]-2-(thiophen-2-yl)acetamide chemical structure, C14H15NOS, CAS 349429-04-5
N-[(4-Methylphenyl)methyl]-2-(thiophen-2-yl)acetamide
CAS 349429-04-5C14H15NOS
N-[(4-Sulfamoylphenyl)methyl]-2-thiophen-2-ylacetamide chemical structure, C13H14N2O3S2, CAS 349433-06-3
N-[(4-Sulfamoylphenyl)methyl]-2-thiophen-2-ylacetamide
CAS 349433-06-3C13H14N2O3S2
N-[(4-Fluorophenyl)methyl]-2-thiophen-2-ylacetamide chemical structure, C13H12FNOS, CAS 434305-31-4
N-[(4-Fluorophenyl)methyl]-2-thiophen-2-ylacetamide
CAS 434305-31-4C13H12FNOS
N-(4-Chlorobenzyl)-2-(thiophen-2-yl)acetamide chemical structure, C13H12ClNOS, CAS 432510-91-3
N-(4-Chlorobenzyl)-2-(thiophen-2-yl)acetamide
CAS 432510-91-3C13H12ClNOS
N-(1-Phenylethyl)-2-thiophen-2-ylacetamide chemical structure, C14H15NOS, CAS 349420-43-5
N-(1-Phenylethyl)-2-thiophen-2-ylacetamide
CAS 349420-43-5C14H15NOS
3-{(R)-(Dihydroxyboryl)[(2-thienylacetyl)amino]methyl}benzoic acid chemical structure, C14H14BNO5S, CAS 497258-67-0
3-{(R)-(Dihydroxyboryl)[(2-thienylacetyl)amino]methyl}benzoic acid
CAS 497258-67-0C14H14BNO5S
N-[1-(4-Propan-2-ylphenyl)ethyl]-2-thiophen-2-ylacetamide chemical structure, C17H21NOS, CAS 894647-90-6
N-[1-(4-Propan-2-ylphenyl)ethyl]-2-thiophen-2-ylacetamide
CAS 894647-90-6C17H21NOS
N-[(3,4-Dimethoxyphenyl)methyl]-2-thiophen-2-ylacetamide chemical structure, C15H17NO3S, CAS 878227-19-1
N-[(3,4-Dimethoxyphenyl)methyl]-2-thiophen-2-ylacetamide
CAS 878227-19-1C15H17NO3S
N-[1-(4-Fluorophenyl)ethyl]-2-(thiophen-2-yl)acetamide chemical structure, C14H14FNOS, CAS 923747-52-8
N-[1-(4-Fluorophenyl)ethyl]-2-(thiophen-2-yl)acetamide
CAS 923747-52-8C14H14FNOS
N-[1-(2,5-Dimethoxyphenyl)ethyl]-2-(thiophen-2-yl)acetamide chemical structure, C16H19NO3S, CAS 925588-86-9
N-[1-(2,5-Dimethoxyphenyl)ethyl]-2-(thiophen-2-yl)acetamide
CAS 925588-86-9C16H19NO3S
N-Benzyl-2-(5-chlorothiophen-2-yl)acetamide chemical structure, C13H12ClNOS, CAS 921797-87-7
N-Benzyl-2-(5-chlorothiophen-2-yl)acetamide
CAS 921797-87-7C13H12ClNOS
N-[1-(4-Chlorophenyl)ethyl]-2-(thiophen-2-yl)acetamide chemical structure, C14H14ClNOS, CAS 926412-99-9
N-[1-(4-Chlorophenyl)ethyl]-2-(thiophen-2-yl)acetamide
CAS 926412-99-9C14H14ClNOS
N-(4-Cyanobenzyl)-2-(thiophen-2-yl)acetamide chemical structure, C14H12N2OS, CAS 1210386-46-1
N-(4-Cyanobenzyl)-2-(thiophen-2-yl)acetamide
CAS 1210386-46-1C14H12N2OS
N-Benzyl-N-(cyanomethyl)-2-(thiophen-2-yl)acetamide chemical structure, C15H14N2OS, CAS 1252265-15-8
N-Benzyl-N-(cyanomethyl)-2-(thiophen-2-yl)acetamide
CAS 1252265-15-8C15H14N2OS
N-[(3-Bromophenyl)(cyano)methyl]-2-(thiophen-2-yl)acetamide chemical structure, C14H11BrN2OS, CAS 1311819-88-1
N-[(3-Bromophenyl)(cyano)methyl]-2-(thiophen-2-yl)acetamide
CAS 1311819-88-1C14H11BrN2OS
N-[Cyano(2,3-dimethoxyphenyl)methyl]-2-(5-methylthiophen-2-yl)acetamide chemical structure, C17H18N2O3S, CAS 1333672-91-5
N-[Cyano(2,3-dimethoxyphenyl)methyl]-2-(5-methylthiophen-2-yl)acetamide
CAS 1333672-91-5C17H18N2O3S
N-Benzyl-2-(5-bromothiophen-2-yl)-N-(cyanomethyl)acetamide chemical structure, C15H13BrN2OS, CAS 1375975-63-5
N-Benzyl-2-(5-bromothiophen-2-yl)-N-(cyanomethyl)acetamide
CAS 1375975-63-5C15H13BrN2OS
2-(5-Chlorothiophen-2-yl)-N-[cyano(4-fluorophenyl)methyl]acetamide chemical structure, C14H10ClFN2OS, CAS 1808703-58-3
2-(5-Chlorothiophen-2-yl)-N-[cyano(4-fluorophenyl)methyl]acetamide
CAS 1808703-58-3C14H10ClFN2OS