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Murcko scaffold

2-[2-(1,3-Thiazol-4-yl)ethyl]-1H-isoindole-1,3(2H)-dione scaffold

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
10
With full pages
4
Scaffold SMILES

O=C1c2ccccc2C(=O)N1CCc1cscn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-[2-(1,3-Thiazol-4-yl)ethyl]-1H-isoindole-1,3(2H)-dione page
Murcko scaffold O=C1c2ccccc2C(=O)N1CCc1cscn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

N-{4-[2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl]-1,3-thiazol-2-yl}acetamide chemical structure, C15H13N3O3S, CAS 861211-17-8
N-{4-[2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl]-1,3-thiazol-2-yl}acetamide
CAS 861211-17-8C15H13N3O3S
2-{2-[2-(Methylamino)-1,3-thiazol-4-yl]ethyl}-1H-isoindole-1,3(2H)-dione chemical structure, C14H13N3O2S, CAS 861211-18-9
2-{2-[2-(Methylamino)-1,3-thiazol-4-yl]ethyl}-1H-isoindole-1,3(2H)-dione
CAS 861211-18-9C14H13N3O2S
2-[2-(2-Methyl-1,3-thiazol-4-yl)ethyl]-1H-isoindole-1,3(2H)-dione chemical structure, C14H12N2O2S, CAS 524704-33-4
2-[2-(2-Methyl-1,3-thiazol-4-yl)ethyl]-1H-isoindole-1,3(2H)-dione
CAS 524704-33-4C14H12N2O2S
2-[2-(1,3-Thiazol-4-yl)ethyl]-1H-isoindole-1,3(2H)-dione chemical structure, C13H10N2O2S, CAS 250258-56-1
2-[2-(1,3-Thiazol-4-yl)ethyl]-1H-isoindole-1,3(2H)-dione
CAS 250258-56-1C13H10N2O2S
2-[2-(2-Amino-1,3-thiazol-4-yl)ethyl]-1H-isoindole-1,3(2H)-dione chemical structure, C13H11N3O2S, CAS 91902-14-6
2-[2-(2-Amino-1,3-thiazol-4-yl)ethyl]-1H-isoindole-1,3(2H)-dione
CAS 91902-14-6C13H11N3O2S
2-[2-(2-Amino-1,3-thiazol-4-yl)ethyl]-1H-isoindole-1,3(2H)-dione hydrobromide chemical structure, C13H12BrN3O2S, CAS 95914-09-3
2-[2-(2-Amino-1,3-thiazol-4-yl)ethyl]-1H-isoindole-1,3(2H)-dione hydrobromide
CAS 95914-09-3C13H12BrN3O2S
N''-{4-[2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl]-1,3-thiazol-2-yl}guanidine chemical structure, C14H13N5O2S, CAS 787496-83-7
N''-{4-[2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl]-1,3-thiazol-2-yl}guanidine
CAS 787496-83-7C14H13N5O2S
4-Chloro-N-[4-[2-(1,3-dioxoisoindol-2-yl)ethyl]-1,3-thiazol-2-yl]butanamide chemical structure, C17H16ClN3O3S, CAS 866050-85-3
4-Chloro-N-[4-[2-(1,3-dioxoisoindol-2-yl)ethyl]-1,3-thiazol-2-yl]butanamide
CAS 866050-85-3C17H16ClN3O3S
2-(2-(2-Aminothiazol-4-yl)ethyl)isoindoline-1,3-dione hydrochloride chemical structure, C13H12ClN3O2S, CAS 137118-00-4
2-(2-(2-Aminothiazol-4-yl)ethyl)isoindoline-1,3-dione hydrochloride
CAS 137118-00-4C13H12ClN3O2S
2-[2-(2-Methyl-1,3-thiazol-4-yl)ethyl]-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride chemical structure, C14H13ClN2O2S, CAS 1803561-26-3
2-[2-(2-Methyl-1,3-thiazol-4-yl)ethyl]-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride
CAS 1803561-26-3C14H13ClN2O2S