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Murcko scaffold

Ring system with 3 rings and 17 atoms

48 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
48
With full pages
0
Scaffold SMILES

O=c1ccc2cccnc2n1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccc2cccnc2n1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 48 chemicals

Sch 33303 chemical structure, C19H16N2O3, CAS 89108-58-7
Sch 33303
CAS 89108-58-7C19H16N2O3
UP 5145-52 chemical structure, C20H20N2O3, CAS 113206-32-9
UP 5145-52
CAS 113206-32-9C20H20N2O3
1,8-Naphthyridin-2(1H)-one, 3-methyl-1-(3-(trifluoromethyl)phenyl)- chemical structure, C16H11F3N2O, CAS 104902-33-2
1,8-Naphthyridin-2(1H)-one, 3-methyl-1-(3-(trifluoromethyl)phenyl)-
CAS 104902-33-2C16H11F3N2O
1,8-Naphthyridin-2(1H)-one, 1-(3-(trifluoromethyl)phenyl)- chemical structure, C15H9F3N2O, CAS 104902-34-3
1,8-Naphthyridin-2(1H)-one, 1-(3-(trifluoromethyl)phenyl)-
CAS 104902-34-3C15H9F3N2O
1,8-Naphthyridin-2(1H)-one, 3-methyl-1-phenyl- chemical structure, C15H12N2O, CAS 116288-88-1
1,8-Naphthyridin-2(1H)-one, 3-methyl-1-phenyl-
CAS 116288-88-1C15H12N2O
1,8-Naphthyridin-2(1H)-one, 1-phenyl-4-(2-propenyloxy)- chemical structure, C17H14N2O2, CAS 89109-18-2
1,8-Naphthyridin-2(1H)-one, 1-phenyl-4-(2-propenyloxy)-
CAS 89109-18-2C17H14N2O2
4-Chloro-1-phenyl-1,8-naphthyridin-2(1H)-one chemical structure, C14H9ClN2O, CAS 583031-58-7
4-Chloro-1-phenyl-1,8-naphthyridin-2(1H)-one
CAS 583031-58-7C14H9ClN2O
3-Butyl-4-(2-hydroxyethoxy)-1-phenyl-1,8-naphthyridin-2(1H)-one chemical structure, C20H22N2O3, CAS 89108-54-3
3-Butyl-4-(2-hydroxyethoxy)-1-phenyl-1,8-naphthyridin-2(1H)-one
CAS 89108-54-3C20H22N2O3
3-(3-Methyl-2-oxo-1,8-naphthyridin-1(2H)-yl)benzonitrile chemical structure, C16H11N3O, CAS 113168-76-6
3-(3-Methyl-2-oxo-1,8-naphthyridin-1(2H)-yl)benzonitrile
CAS 113168-76-6C16H11N3O
5-(2-Oxo-1-phenyl-1,2-dihydro-1,8-naphthyridin-3-yl)pentanoic acid chemical structure, C19H18N2O3, CAS 113168-87-9
5-(2-Oxo-1-phenyl-1,2-dihydro-1,8-naphthyridin-3-yl)pentanoic acid
CAS 113168-87-9C19H18N2O3
3-(2-Hydroxyethyl)-1-phenyl-1,8-naphthyridin-2(1H)-one chemical structure, C16H14N2O2, CAS 113206-26-1
3-(2-Hydroxyethyl)-1-phenyl-1,8-naphthyridin-2(1H)-one
CAS 113206-26-1C16H14N2O2
3-(Non-8-en-1-yl)-2-oxo-1-phenyl-1,2-dihydro-1,8-naphthyridin-4-yl acetate chemical structure, C25H28N2O3, CAS 89108-78-1
3-(Non-8-en-1-yl)-2-oxo-1-phenyl-1,2-dihydro-1,8-naphthyridin-4-yl acetate
CAS 89108-78-1C25H28N2O3
3-Butyl-4-ethoxy-1-phenyl-1,8-naphthyridin-2(1H)-one chemical structure, C20H22N2O2, CAS 89108-86-1
3-Butyl-4-ethoxy-1-phenyl-1,8-naphthyridin-2(1H)-one
CAS 89108-86-1C20H22N2O2
3-Butyl-4-(2,3-dihydroxypropoxy)-1-phenyl-1,8-naphthyridin-2(1H)-one chemical structure, C21H24N2O4, CAS 89108-71-4
3-Butyl-4-(2,3-dihydroxypropoxy)-1-phenyl-1,8-naphthyridin-2(1H)-one
CAS 89108-71-4C21H24N2O4
3-Butyl-4-(3-hydroxypropoxy)-1-phenyl-1,8-naphthyridin-2(1H)-one chemical structure, C21H24N2O3, CAS 89108-72-5
3-Butyl-4-(3-hydroxypropoxy)-1-phenyl-1,8-naphthyridin-2(1H)-one
CAS 89108-72-5C21H24N2O3
3-Butyl-1-phenyl-4-[(prop-2-en-1-yl)oxy]-1,8-naphthyridin-2(1H)-one chemical structure, C21H22N2O2, CAS 89108-70-3
3-Butyl-1-phenyl-4-[(prop-2-en-1-yl)oxy]-1,8-naphthyridin-2(1H)-one
CAS 89108-70-3C21H22N2O2
3-Butyl-1-phenyl-4-[(prop-2-yn-1-yl)oxy]-1,8-naphthyridin-2(1H)-one chemical structure, C21H20N2O2, CAS 89108-65-6
3-Butyl-1-phenyl-4-[(prop-2-yn-1-yl)oxy]-1,8-naphthyridin-2(1H)-one
CAS 89108-65-6C21H20N2O2
1-Phenyl-3-(prop-2-yn-1-yl)-4-[(prop-2-yn-1-yl)oxy]-1,8-naphthyridin-2(1H)-one chemical structure, C20H14N2O2, CAS 89109-09-1
1-Phenyl-3-(prop-2-yn-1-yl)-4-[(prop-2-yn-1-yl)oxy]-1,8-naphthyridin-2(1H)-one
CAS 89109-09-1C20H14N2O2
4-Amino-3-nitro-1-phenyl-1,8-naphthyridin-2(1H)-one chemical structure, C14H10N4O3, CAS 139339-01-8
4-Amino-3-nitro-1-phenyl-1,8-naphthyridin-2(1H)-one
CAS 139339-01-8C14H10N4O3
3-(2-Chloroethyl)-1-[3-(trifluoromethyl)phenyl]-1,8-naphthyridin-2-one chemical structure, C17H12ClF3N2O, CAS 135634-30-9
3-(2-Chloroethyl)-1-[3-(trifluoromethyl)phenyl]-1,8-naphthyridin-2-one
CAS 135634-30-9C17H12ClF3N2O
2-Oxo-1-phenyl-1,2-dihydro-1,8-naphthyridine-3-carboxylic acid chemical structure, C15H10N2O3, CAS 1239164-92-1
2-Oxo-1-phenyl-1,2-dihydro-1,8-naphthyridine-3-carboxylic acid
CAS 1239164-92-1C15H10N2O3
Ethyl 4-hydroxy-2-oxo-1-phenyl-1,2-dihydro-1,8-naphthyridine-3-carboxylate chemical structure, C17H14N2O4, CAS 138305-20-1
Ethyl 4-hydroxy-2-oxo-1-phenyl-1,2-dihydro-1,8-naphthyridine-3-carboxylate
CAS 138305-20-1C17H14N2O4
4-Hydroxy-1-phenyl-3-(prop-2-en-1-yl)-1,8-naphthyridin-2(1H)-one chemical structure, C17H14N2O2, CAS 89108-63-4
4-Hydroxy-1-phenyl-3-(prop-2-en-1-yl)-1,8-naphthyridin-2(1H)-one
CAS 89108-63-4C17H14N2O2
4-Hydroxy-1-phenyl-1,8-naphthyridin-2(1H)-one chemical structure, C14H10N2O2, CAS 89109-17-1
4-Hydroxy-1-phenyl-1,8-naphthyridin-2(1H)-one
CAS 89109-17-1C14H10N2O2