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Murcko scaffold

1,3-Dihydro-1-(4-piperidinyl)-2H-benzimidazol-2-one scaffold

964 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
964
With full pages
8
Scaffold SMILES

O=c1[nH]c2ccccc2n1C1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,3-Dihydro-1-(4-piperidinyl)-2H-benzimidazol-2-one page
Murcko scaffold O=c1[nH]c2ccccc2n1C1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 964 chemicals

1,3-Dihydro-1-(4-piperidinyl)-2H-benzimidazol-2-one chemical structure, C12H15N3O, CAS 20662-53-7
1,3-Dihydro-1-(4-piperidinyl)-2H-benzimidazol-2-one
CAS 20662-53-7C12H15N3O
5-Chloro-1,3-dihydro-1-(4-piperidinyl)-2H-benzimidazol-2-one chemical structure, C12H14ClN3O, CAS 53786-28-0
5-Chloro-1,3-dihydro-1-(4-piperidinyl)-2H-benzimidazol-2-one
CAS 53786-28-0C12H14ClN3O
Ethyl 4-(5-chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinecarboxylate chemical structure, C15H18ClN3O3, CAS 53786-46-2
Ethyl 4-(5-chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinecarboxylate
CAS 53786-46-2C15H18ClN3O3
Ethyl 4-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)piperidine-1-carboxylate chemical structure, C15H19N3O3, CAS 53786-47-3
Ethyl 4-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)piperidine-1-carboxylate
CAS 53786-47-3C15H19N3O3
Dihydrobenzimidazol-2-one, 1-acetyl-3, (1-acetyl-4-pyperidyl)- chemical structure, C16H19N3O3, CAS 959029-13-1
Dihydrobenzimidazol-2-one, 1-acetyl-3, (1-acetyl-4-pyperidyl)-
CAS 959029-13-1C16H19N3O3
1-(1-(2-(Isobutylamino)acetyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one chemical structure, C18H26N4O2, CAS 1022576-93-7
1-(1-(2-(Isobutylamino)acetyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
CAS 1022576-93-7C18H26N4O2
1-(1-(3-(tert-Butoxy)-2-hydroxypropyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one chemical structure, C19H29N3O3, CAS 1022112-04-4
1-(1-(3-(tert-Butoxy)-2-hydroxypropyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
CAS 1022112-04-4C19H29N3O3
1-(1-(Isopropylsulfonyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one chemical structure, C15H21N3O3S, CAS 1022244-10-5
1-(1-(Isopropylsulfonyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
CAS 1022244-10-5C15H21N3O3S
N-Butyl-4-(2,3-dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)piperidin-1-carboxamide chemical structure, C17H24N4O2, CAS 1022396-20-8
N-Butyl-4-(2,3-dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)piperidin-1-carboxamide
CAS 1022396-20-8C17H24N4O2
1-(1-(3-(Allyloxy)-2-hydroxypropyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one chemical structure, C18H25N3O3, CAS 1022877-09-3
1-(1-(3-(Allyloxy)-2-hydroxypropyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
CAS 1022877-09-3C18H25N3O3
1-(1-(2-Hydroxy-3-isobutoxypropyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one chemical structure, C19H29N3O3, CAS 1022035-53-5
1-(1-(2-Hydroxy-3-isobutoxypropyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
CAS 1022035-53-5C19H29N3O3
1,3-Dihydro-1-[1-[2-hydroxy-3-(Propargyloxy)-propyl]piperidin-4-yl]-2H-benzo[d]imidazol-2-one chemical structure, C18H23N3O3, CAS 1022765-21-4
1,3-Dihydro-1-[1-[2-hydroxy-3-(Propargyloxy)-propyl]piperidin-4-yl]-2H-benzo[d]imidazol-2-one
CAS 1022765-21-4C18H23N3O3
Ethyl N-[[4-(2,3-dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)piperidin-1-yl]carbonyl]carbamate chemical structure, C16H20N4O4, CAS 1022560-51-5
Ethyl N-[[4-(2,3-dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)piperidin-1-yl]carbonyl]carbamate
CAS 1022560-51-5C16H20N4O4
1-(1-(3-Butoxy-2-hydroxypropyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one chemical structure, C19H29N3O3, CAS 1022348-71-5
1-(1-(3-Butoxy-2-hydroxypropyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
CAS 1022348-71-5C19H29N3O3
1-(1-(2-(Propylamino)acetyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one chemical structure, C17H24N4O2, CAS 1024070-09-4
1-(1-(2-(Propylamino)acetyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
CAS 1024070-09-4C17H24N4O2
3-(1-Butylpiperidin-4-yl)-1H-benzimidazol-2-one chemical structure, C16H23N3O, CAS 198969-51-6
3-(1-Butylpiperidin-4-yl)-1H-benzimidazol-2-one
CAS 198969-51-6C16H23N3O
NS 521 oxalate chemical structure, C18H25N3O5, CAS 198969-52-7
NS 521 oxalate
CAS 198969-52-7C18H25N3O5
1-Acetyl-3-(1-(4-methylhexan-2-yl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one chemical structure, C21H31N3O2, CAS 343614-48-2
1-Acetyl-3-(1-(4-methylhexan-2-yl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
CAS 343614-48-2C21H31N3O2
6-Methyl-1-(piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one chemical structure, C13H17N3O, CAS 85076-01-3
6-Methyl-1-(piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
CAS 85076-01-3C13H17N3O
2,2-Dimethyl-2-[4-(2-keto-1-benzimidazolinyl)piperidinyl]acetonitrile chemical structure, C16H20N4O, CAS 231961-50-5
2,2-Dimethyl-2-[4-(2-keto-1-benzimidazolinyl)piperidinyl]acetonitrile
CAS 231961-50-5C16H20N4O
tert-Butyl 4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidine-1-carboxylate chemical structure, C17H23N3O3, CAS 87120-81-8
tert-Butyl 4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidine-1-carboxylate
CAS 87120-81-8C17H23N3O3
tert-Butyl 4-(3-ethyl-2,3-dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)-1-piperidinecarboxylate chemical structure, C19H27N3O3, CAS 87120-84-1
tert-Butyl 4-(3-ethyl-2,3-dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)-1-piperidinecarboxylate
CAS 87120-84-1C19H27N3O3
1-(1-(3-Chloropropyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one chemical structure, C15H20ClN3O, CAS 61293-50-3
1-(1-(3-Chloropropyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
CAS 61293-50-3C15H20ClN3O
4-(2,3-Dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)-1-piperidinecarbothioaldehyde chemical structure, C13H15N3OS, CAS 107046-80-0
4-(2,3-Dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)-1-piperidinecarbothioaldehyde
CAS 107046-80-0C13H15N3OS