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Murcko scaffold

Ring system with 3 rings and 19 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
8
With full pages
3
Scaffold SMILES

c1ccc(SCc2cc(-c3ccccc3)on2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(SCc2cc(-c3ccccc3)on2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

5-(4-Chlorophenyl)-3-{[(4-methylphenyl)sulfanyl]methyl}isoxazole chemical structure, C17H14ClNOS, CAS 551921-52-9
5-(4-Chlorophenyl)-3-{[(4-methylphenyl)sulfanyl]methyl}isoxazole
CAS 551921-52-9C17H14ClNOS
5-(4-Chlorophenyl)-3-{[(4-chlorophenyl)sulfanyl]methyl}isoxazole chemical structure, C16H11Cl2NOS, CAS 4714-78-7
5-(4-Chlorophenyl)-3-{[(4-chlorophenyl)sulfanyl]methyl}isoxazole
CAS 4714-78-7C16H11Cl2NOS
5-(3,4-Dichlorophenyl)-3-[(phenylsulfanyl)methyl]isoxazole chemical structure, C16H11Cl2NOS, CAS 339019-68-0
5-(3,4-Dichlorophenyl)-3-[(phenylsulfanyl)methyl]isoxazole
CAS 339019-68-0C16H11Cl2NOS
5-(2-Chlorophenyl)-3-{[(4-chlorophenyl)sulfanyl]methyl}isoxazole chemical structure, C16H11Cl2NOS, CAS 339019-70-4
5-(2-Chlorophenyl)-3-{[(4-chlorophenyl)sulfanyl]methyl}isoxazole
CAS 339019-70-4C16H11Cl2NOS
4-Chlorophenyl (5-phenyl-3-isoxazolyl)methyl sulfide chemical structure, C16H12ClNOS, CAS 478067-78-6
4-Chlorophenyl (5-phenyl-3-isoxazolyl)methyl sulfide
CAS 478067-78-6C16H12ClNOS
3-{[(4-Bromophenyl)sulfanyl]methyl}-5-phenylisoxazole chemical structure, C16H12BrNOS, CAS 339019-74-8
3-{[(4-Bromophenyl)sulfanyl]methyl}-5-phenylisoxazole
CAS 339019-74-8C16H12BrNOS
5-(2-Chlorophenyl)-3-{[(2,5-dichlorophenyl)sulfanyl]methyl}isoxazole chemical structure, C16H10Cl3NOS, CAS 339019-71-5
5-(2-Chlorophenyl)-3-{[(2,5-dichlorophenyl)sulfanyl]methyl}isoxazole
CAS 339019-71-5C16H10Cl3NOS
4-(tert-Butyl)phenyl [5-(3,4-dichlorophenyl)-3-isoxazolyl]methyl sulfide chemical structure, C20H19Cl2NOS, CAS 478067-77-5
4-(tert-Butyl)phenyl [5-(3,4-dichlorophenyl)-3-isoxazolyl]methyl sulfide
CAS 478067-77-5C20H19Cl2NOS