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Murcko scaffold

N-(5-Phenyl-1,3,4-oxadiazol-2-yl)-5,6-dihydro-1,4-dioxine-2-carboxamide scaffold

17 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 20
Chemicals: 17
With full pages: 11

Scaffold SMILES

O=C(Nc1nnc(-c2ccccc2)o1)C1=COCCO1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the N-(5-Phenyl-1,3,4-oxadiazol-2-yl)-5,6-dihydro-1,4-dioxine-2-carboxamide page

Murcko scaffold O=C(Nc1nnc(-c2ccccc2)o1)C1=COCCO1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

N-[5-(2-Methoxyphenyl)-1,3,4-oxadiazol-2-yl]-5,6-dihydro-1,4-dioxine-2-carboxamide chemical structure, C14H13N3O5, CAS 865286-17-5

N-[5-(2-Methoxyphenyl)-1,3,4-oxadiazol-2-yl]-5,6-dihydro-1,4-dioxine-2-carboxamide

CAS 865286-17-5C₁₄H₁₃N₃O₅

N-(5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl)-5,6-dihydro-1,4-dioxine-2-carboxamide chemical structure, C13H10ClN3O4, CAS 865287-29-2

N-(5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl)-5,6-dihydro-1,4-dioxine-2-carboxamide

CAS 865287-29-2C₁₃H₁₀ClN₃O₄

N-(5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl)-5,6-dihydro-1,4-dioxine-2-carboxamide chemical structure, C13H10ClN3O4, CAS 865249-71-4

N-(5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl)-5,6-dihydro-1,4-dioxine-2-carboxamide

CAS 865249-71-4C₁₃H₁₀ClN₃O₄

N-(5-Phenyl-1,3,4-oxadiazol-2-yl)-5,6-dihydro-1,4-dioxine-2-carboxamide chemical structure, C13H11N3O4, CAS 865287-61-2

N-(5-Phenyl-1,3,4-oxadiazol-2-yl)-5,6-dihydro-1,4-dioxine-2-carboxamide

CAS 865287-61-2C₁₃H₁₁N₃O₄

N-[5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl]-2,3-dihydro-1,4-dioxine-5-carboxamide chemical structure, C14H13N3O5, CAS 865286-81-3

N-[5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl]-2,3-dihydro-1,4-dioxine-5-carboxamide

CAS 865286-81-3C₁₄H₁₃N₃O₅

N-(5-(3,4,5-Triethoxyphenyl)-1,3,4-oxadiazol-2-yl)-5,6-dihydro-1,4-dioxine-2-carboxamide chemical structure, C19H23N3O7, CAS 891130-79-3

N-(5-(3,4,5-Triethoxyphenyl)-1,3,4-oxadiazol-2-yl)-5,6-dihydro-1,4-dioxine-2-carboxamide

CAS 891130-79-3C₁₉H₂₃N₃O₇

N-[5-(2,5-Dichlorophenyl)-1,3,4-oxadiazol-2-yl]-5,6-dihydro-1,4-dioxine-2-carboxamide chemical structure, C13H9Cl2N3O4, CAS 891141-30-3

N-[5-(2,5-Dichlorophenyl)-1,3,4-oxadiazol-2-yl]-5,6-dihydro-1,4-dioxine-2-carboxamide

CAS 891141-30-3C₁₃H₉Cl₂N₃O₄

N-[5-(2,4-Dimethylphenyl)-1,3,4-oxadiazol-2-yl]-2,3-dihydro-1,4-dioxine-5-carboxamide chemical structure, C15H15N3O4, CAS 891115-55-2

N-[5-(2,4-Dimethylphenyl)-1,3,4-oxadiazol-2-yl]-2,3-dihydro-1,4-dioxine-5-carboxamide

CAS 891115-55-2C₁₅H₁₅N₃O₄

N-(5-(3,4,5-Trimethoxyphenyl)-1,3,4-oxadiazol-2-yl)-5,6-dihydro-1,4-dioxine-2-carboxamide chemical structure, C16H17N3O7, CAS 891123-02-7

N-(5-(3,4,5-Trimethoxyphenyl)-1,3,4-oxadiazol-2-yl)-5,6-dihydro-1,4-dioxine-2-carboxamide

CAS 891123-02-7C₁₆H₁₇N₃O₇

N-[5-(4-Bromophenyl)-1,3,4-oxadiazol-2-yl]-5,6-dihydro-1,4-dioxine-2-carboxamide chemical structure, C13H10BrN3O4, CAS 897619-76-0

N-[5-(4-Bromophenyl)-1,3,4-oxadiazol-2-yl]-5,6-dihydro-1,4-dioxine-2-carboxamide

CAS 897619-76-0C₁₃H₁₀BrN₃O₄

N-[5-(2-Methylsulfonylphenyl)-1,3,4-oxadiazol-2-yl]-2,3-dihydro-1,4-dioxine-5-carboxamide chemical structure, C14H13N3O6S, CAS 886925-60-6

N-[5-(2-Methylsulfonylphenyl)-1,3,4-oxadiazol-2-yl]-2,3-dihydro-1,4-dioxine-5-carboxamide

CAS 886925-60-6C₁₄H₁₃N₃O₆S

N-[5-(3-Methylsulfonylphenyl)-1,3,4-oxadiazol-2-yl]-2,3-dihydro-1,4-dioxine-5-carboxamide chemical structure, C14H13N3O6S, CAS 886907-82-0

N-[5-(3-Methylsulfonylphenyl)-1,3,4-oxadiazol-2-yl]-2,3-dihydro-1,4-dioxine-5-carboxamide

CAS 886907-82-0C₁₄H₁₃N₃O₆S

N-[5-(4-Methylsulfonylphenyl)-1,3,4-oxadiazol-2-yl]-2,3-dihydro-1,4-dioxine-5-carboxamide chemical structure, C14H13N3O6S, CAS 886914-13-2

N-[5-(4-Methylsulfonylphenyl)-1,3,4-oxadiazol-2-yl]-2,3-dihydro-1,4-dioxine-5-carboxamide

CAS 886914-13-2C₁₄H₁₃N₃O₆S

N-[5-(3,4-Dimethylphenyl)-1,3,4-oxadiazol-2-yl]-5,6-dihydro-1,4-dioxine-2-carboxamide chemical structure, C15H15N3O4, CAS 899734-60-2

N-[5-(3,4-Dimethylphenyl)-1,3,4-oxadiazol-2-yl]-5,6-dihydro-1,4-dioxine-2-carboxamide

CAS 899734-60-2C₁₅H₁₅N₃O₄

N-(5-(2,4-Difluorophenyl)-1,3,4-oxadiazol-2-yl)-5,6-dihydro-1,4-dioxine-2-carboxamide chemical structure, C13H9F2N3O4, CAS 1171466-09-3

N-(5-(2,4-Difluorophenyl)-1,3,4-oxadiazol-2-yl)-5,6-dihydro-1,4-dioxine-2-carboxamide

CAS 1171466-09-3C₁₃H₉F₂N₃O₄

N-(5-(3,5-Dimethylphenyl)-1,3,4-oxadiazol-2-yl)-5,6-dihydro-1,4-dioxine-2-carboxamide chemical structure, C15H15N3O4, CAS 1170944-74-7

N-(5-(3,5-Dimethylphenyl)-1,3,4-oxadiazol-2-yl)-5,6-dihydro-1,4-dioxine-2-carboxamide

CAS 1170944-74-7C₁₅H₁₅N₃O₄

N-(5-(4-(N,N-Dimethylsulfamoyl)phenyl)-1,3,4-oxadiazol-2-yl)-5,6-dihydro-1,4-dioxine-2-carboxamide chemical structure, C15H16N4O6S, CAS 1170093-61-4

N-(5-(4-(N,N-Dimethylsulfamoyl)phenyl)-1,3,4-oxadiazol-2-yl)-5,6-dihydro-1,4-dioxine-2-carboxamide

CAS 1170093-61-4C₁₅H₁₆N₄O₆S