Murcko scaffold
Ring system with 3 rings and 17 atoms
388 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 17
- Chemicals
- 388
- With full pages
- 4
Scaffold SMILES
O=C(Nc1nc2ccccc2s1)c1ccn[nH]1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold O=C(Nc1nc2ccccc2s1)c1ccn[nH]1](/scaffold/CSTPNIPYKLCOLF-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 49 to 96 of 388 chemicals
![N-(4,6-Difluorobenzo[d]thiazol-2-yl)-N-(2-(dimethylamino)ethyl)-1,5-dimethyl-1H-pyrazole-3-carboxamide hydrochloride chemical structure, C17H20ClF2N5OS, CAS 1217178-85-2](/s/BCHZZILDCUZOQZ-UHFFFAOYSA-N.svg)
N-(4,6-Difluorobenzo[d]thiazol-2-yl)-N-(2-(dimethylamino)ethyl)-1,5-dimethyl-1H-pyrazole-3-carboxamide hydrochloride
CAS 1217178-85-2C17H20ClF2N5OS
![N-(2-(Diethylamino)ethyl)-N-(4,6-difluorobenzo[d]thiazol-2-yl)-1,5-dimethyl-1H-pyrazole-3-carboxamide hydrochloride chemical structure, C19H24ClF2N5OS, CAS 1216788-34-9](/s/CGKFHNWNKLOGEF-UHFFFAOYSA-N.svg)
N-(2-(Diethylamino)ethyl)-N-(4,6-difluorobenzo[d]thiazol-2-yl)-1,5-dimethyl-1H-pyrazole-3-carboxamide hydrochloride
CAS 1216788-34-9C19H24ClF2N5OS
![N-(4,6-Difluorobenzo[d]thiazol-2-yl)-N-(3-(dimethylamino)propyl)-1,5-dimethyl-1H-pyrazole-3-carboxamide hydrochloride chemical structure, C18H22ClF2N5OS, CAS 1215711-65-1](/s/BUDQSFGSGMMAFZ-UHFFFAOYSA-N.svg)
N-(4,6-Difluorobenzo[d]thiazol-2-yl)-N-(3-(dimethylamino)propyl)-1,5-dimethyl-1H-pyrazole-3-carboxamide hydrochloride
CAS 1215711-65-1C18H22ClF2N5OS
![N-(2-(Diethylamino)ethyl)-N-(4-methoxy-7-methylbenzo[d]thiazol-2-yl)-1,5-dimethyl-1H-pyrazole-3-carboxamide hydrochloride chemical structure, C21H30ClN5O2S, CAS 1329870-01-0](/s/SKXFYCQTDQFTHE-UHFFFAOYSA-N.svg)
N-(2-(Diethylamino)ethyl)-N-(4-methoxy-7-methylbenzo[d]thiazol-2-yl)-1,5-dimethyl-1H-pyrazole-3-carboxamide hydrochloride
CAS 1329870-01-0C21H30ClN5O2S
![N-(7-Chloro-4-methoxybenzo[d]thiazol-2-yl)-N-(2-(dimethylamino)ethyl)-1,5-dimethyl-1H-pyrazole-3-carboxamide hydrochloride chemical structure, C18H23Cl2N5O2S, CAS 1216663-04-5](/s/NMMQUUOVKJVMLU-UHFFFAOYSA-N.svg)
N-(7-Chloro-4-methoxybenzo[d]thiazol-2-yl)-N-(2-(dimethylamino)ethyl)-1,5-dimethyl-1H-pyrazole-3-carboxamide hydrochloride
CAS 1216663-04-5C18H23Cl2N5O2S
![N-(7-Chloro-4-methoxybenzo[d]thiazol-2-yl)-N-(3-(dimethylamino)propyl)-1,5-dimethyl-1H-pyrazole-3-carboxamide hydrochloride chemical structure, C19H25Cl2N5O2S, CAS 1215455-76-7](/s/YXECUTQUGQREKX-UHFFFAOYSA-N.svg)
N-(7-Chloro-4-methoxybenzo[d]thiazol-2-yl)-N-(3-(dimethylamino)propyl)-1,5-dimethyl-1H-pyrazole-3-carboxamide hydrochloride
CAS 1215455-76-7C19H25Cl2N5O2S
![N-(Benzo[d]thiazol-2-yl)-N-(2-(dimethylamino)ethyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride chemical structure, C17H22ClN5OS, CAS 1215574-56-3](/s/SREFBHWLTWTZDA-UHFFFAOYSA-N.svg)
N-(Benzo[d]thiazol-2-yl)-N-(2-(dimethylamino)ethyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride
CAS 1215574-56-3C17H22ClN5OS
![N-(Benzo[d]thiazol-2-yl)-N-(3-(dimethylamino)propyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride chemical structure, C18H24ClN5OS, CAS 1215453-90-9](/s/JCSMJXPGLTXMMB-UHFFFAOYSA-N.svg)
N-(Benzo[d]thiazol-2-yl)-N-(3-(dimethylamino)propyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride
CAS 1215453-90-9C18H24ClN5OS
![N-[2-(Diethylamino)ethyl]-N-(6-methoxy-1,3-benzothiazol-2-yl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride chemical structure, C20H28ClN5O2S, CAS 1329872-12-9](/s/BKUNXYSLGTUDKN-UHFFFAOYSA-N.svg)
N-[2-(Diethylamino)ethyl]-N-(6-methoxy-1,3-benzothiazol-2-yl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride
CAS 1329872-12-9C20H28ClN5O2S
![N-(6-Chlorobenzo[d]thiazol-2-yl)-N-(2-(diethylamino)ethyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride chemical structure, C19H25Cl2N5OS, CAS 1329860-11-8](/s/YFFFTKBMACSWNH-UHFFFAOYSA-N.svg)
N-(6-Chlorobenzo[d]thiazol-2-yl)-N-(2-(diethylamino)ethyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride
CAS 1329860-11-8C19H25Cl2N5OS
![N-(6-Chlorobenzo[d]thiazol-2-yl)-N-(3-(dimethylamino)propyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride chemical structure, C18H23Cl2N5OS, CAS 1215315-90-4](/s/RNNACKXPCLSNMX-UHFFFAOYSA-N.svg)
N-(6-Chlorobenzo[d]thiazol-2-yl)-N-(3-(dimethylamino)propyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride
CAS 1215315-90-4C18H23Cl2N5OS
![N-(2-(Dimethylamino)ethyl)-N-(6-fluorobenzo[d]thiazol-2-yl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride chemical structure, C17H21ClFN5OS, CAS 1215791-17-5](/s/KIJDPKLXZQSMSF-UHFFFAOYSA-N.svg)
N-(2-(Dimethylamino)ethyl)-N-(6-fluorobenzo[d]thiazol-2-yl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride
CAS 1215791-17-5C17H21ClFN5OS
![N-(2-(Diethylamino)ethyl)-N-(6-fluorobenzo[d]thiazol-2-yl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride chemical structure, C19H25ClFN5OS, CAS 1215559-64-0](/s/FWWNFZQEFSIARN-UHFFFAOYSA-N.svg)
N-(2-(Diethylamino)ethyl)-N-(6-fluorobenzo[d]thiazol-2-yl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride
CAS 1215559-64-0C19H25ClFN5OS
![N-(3-(Dimethylamino)propyl)-N-(6-fluorobenzo[d]thiazol-2-yl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride chemical structure, C18H23ClFN5OS, CAS 1216775-03-9](/s/MKMRJBOACDHFDG-UHFFFAOYSA-N.svg)
N-(3-(Dimethylamino)propyl)-N-(6-fluorobenzo[d]thiazol-2-yl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride
CAS 1216775-03-9C18H23ClFN5OS
![N-(4-Chlorobenzo[d]thiazol-2-yl)-N-(2-(dimethylamino)ethyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride chemical structure, C17H21Cl2N5OS, CAS 1216452-32-2](/s/ZGZOQFQJRNYLMX-UHFFFAOYSA-N.svg)
N-(4-Chlorobenzo[d]thiazol-2-yl)-N-(2-(dimethylamino)ethyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride
CAS 1216452-32-2C17H21Cl2N5OS
![N-(4-Chlorobenzo[d]thiazol-2-yl)-N-(3-(dimethylamino)propyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride chemical structure, C18H23Cl2N5OS, CAS 1215364-20-7](/s/TZKAKUPJJAVEIB-UHFFFAOYSA-N.svg)
N-(4-Chlorobenzo[d]thiazol-2-yl)-N-(3-(dimethylamino)propyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride
CAS 1215364-20-7C18H23Cl2N5OS
![N-(2-(Dimethylamino)ethyl)-N-(4-fluorobenzo[d]thiazol-2-yl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride chemical structure, C17H21ClFN5OS, CAS 1217086-33-3](/s/LUYBWYKOEAEIRK-UHFFFAOYSA-N.svg)
N-(2-(Dimethylamino)ethyl)-N-(4-fluorobenzo[d]thiazol-2-yl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride
CAS 1217086-33-3C17H21ClFN5OS
![N-(3-(Dimethylamino)propyl)-N-(4-fluorobenzo[d]thiazol-2-yl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride chemical structure, C18H23ClFN5OS, CAS 1215604-51-5](/s/ZRLJTZLOVDELMX-UHFFFAOYSA-N.svg)
N-(3-(Dimethylamino)propyl)-N-(4-fluorobenzo[d]thiazol-2-yl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride
CAS 1215604-51-5C18H23ClFN5OS
![N-(4,6-Difluorobenzo[d]thiazol-2-yl)-N-(2-(dimethylamino)ethyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride chemical structure, C17H20ClF2N5OS, CAS 1215628-92-4](/s/FRXXOZKMEGMANU-UHFFFAOYSA-N.svg)
N-(4,6-Difluorobenzo[d]thiazol-2-yl)-N-(2-(dimethylamino)ethyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride
CAS 1215628-92-4C17H20ClF2N5OS
![N-(2-(Diethylamino)ethyl)-N-(4,6-difluorobenzo[d]thiazol-2-yl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride chemical structure, C19H24ClF2N5OS, CAS 1215800-00-2](/s/MVQADHAYIDFXAF-UHFFFAOYSA-N.svg)
N-(2-(Diethylamino)ethyl)-N-(4,6-difluorobenzo[d]thiazol-2-yl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride
CAS 1215800-00-2C19H24ClF2N5OS
![N-(4,6-Difluorobenzo[d]thiazol-2-yl)-N-(3-(dimethylamino)propyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride chemical structure, C18H22ClF2N5OS, CAS 1215811-24-7](/s/GCZPMDTVGYZVJE-UHFFFAOYSA-N.svg)
N-(4,6-Difluorobenzo[d]thiazol-2-yl)-N-(3-(dimethylamino)propyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride
CAS 1215811-24-7C18H22ClF2N5OS
![N-(4,7-Dimethoxybenzo[d]thiazol-2-yl)-N-(3-(dimethylamino)propyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride chemical structure, C20H28ClN5O3S, CAS 1329870-77-0](/s/HHOBMBIOOLLJJE-UHFFFAOYSA-N.svg)
N-(4,7-Dimethoxybenzo[d]thiazol-2-yl)-N-(3-(dimethylamino)propyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride
CAS 1329870-77-0C20H28ClN5O3S
![N-(2-(Dimethylamino)ethyl)-N-(4-methoxy-7-methylbenzo[d]thiazol-2-yl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride chemical structure, C19H26ClN5O2S, CAS 1189505-89-2](/s/HOACMWCGBUSNAW-UHFFFAOYSA-N.svg)
N-(2-(Dimethylamino)ethyl)-N-(4-methoxy-7-methylbenzo[d]thiazol-2-yl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride
CAS 1189505-89-2C19H26ClN5O2S
![N-[2-(Diethylamino)ethyl]-N-(4-methoxy-7-methyl-1,3-benzothiazol-2-yl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride chemical structure, C21H30ClN5O2S, CAS 1329625-10-6](/s/INWMTOPBAAPFBB-UHFFFAOYSA-N.svg)
N-[2-(Diethylamino)ethyl]-N-(4-methoxy-7-methyl-1,3-benzothiazol-2-yl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride
CAS 1329625-10-6C21H30ClN5O2S
- N-(7-Chloro-4-methoxybenzo[d]thiazol-2-yl)-N-(2-(dimethylamino)ethyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride1215505-50-2C18H23Cl2N5O2S
- N-(7-Chloro-4-methoxybenzo[d]thiazol-2-yl)-N-(3-(dimethylamino)propyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride1216438-98-0C19H25Cl2N5O2S
- N-(6-Methoxy-1,3-benzothiazol-2-yl)-1,5-dimethyl-1H-pyrazole-3-carboxamide1013756-73-4C14H14N4O2S
- N-(4-Methoxybenzo[d]thiazol-2-yl)-1,5-dimethyl-1H-pyrazole-3-carboxamide1013756-86-9C14H14N4O2S
- N-(6-Bromobenzo[d]thiazol-2-yl)-1,5-dimethyl-1H-pyrazole-3-carboxamide1013756-96-1C13H11BrN4OS
- 1,5-Dimethyl-N-(6-methylbenzo[d]thiazol-2-yl)-1H-pyrazole-3-carboxamide1013768-85-8C14H14N4OS
- 1,5-Dimethyl-N-(6-sulfamoylbenzo[d]thiazol-2-yl)-1H-pyrazole-3-carboxamide1013757-27-1C13H13N5O3S2
- N-(Benzo[d]thiazol-2-yl)-1,5-dimethyl-1H-pyrazole-3-carboxamide1013758-07-0C13H12N4OS
- N-(6-Acetamidobenzo[d]thiazol-2-yl)-1,5-dimethyl-1H-pyrazole-3-carboxamide1013758-84-3C15H15N5O2S
- 1,5-Dimethyl-N-(3-methylbenzo[d]thiazol-2(3H)-ylidene)-1H-pyrazole-3-carboxamide1019105-75-9C14H14N4OS
- N-(6-Methoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)-1,5-dimethyl-1H-pyrazole-3-carboxamide1020051-62-0C15H16N4O2S
- N-(4,5-Dichlorobenzo[d]thiazol-2-yl)-1,5-dimethyl-1H-pyrazole-3-carboxamide1013784-73-0C13H10Cl2N4OS
- N-(4,7-Dimethoxybenzo[d]thiazol-2-yl)-1,5-dimethyl-1H-pyrazole-3-carboxamide1013785-46-0C15H16N4O3S
- N-(5,6-Dimethoxybenzo[d]thiazol-2-yl)-1,5-dimethyl-1H-pyrazole-3-carboxamide1013795-64-6C15H16N4O3S
- N-(6-Ethoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)-1,5-dimethyl-1H-pyrazole-3-carboxamide1173482-21-7C16H18N4O2S
- N-(6-Fluoro-3-methylbenzo[d]thiazol-2(3H)-ylidene)-1,5-dimethyl-1H-pyrazole-3-carboxamide1020051-64-2C14H13FN4OS
- N-(3-Ethyl-6-methoxybenzo[d]thiazol-2(3H)-ylidene)-1,5-dimethyl-1H-pyrazole-3-carboxamide1173516-48-7C16H18N4O2S
- Ethyl 2-((1,5-dimethyl-1H-pyrazole-3-carbonyl)imino)-3-ethyl-2,3-dihydrobenzo[d]thiazole-6-carboxylate1173390-26-5C18H20N4O3S
- Methyl 2-((1,5-dimethyl-1H-pyrazole-3-carbonyl)imino)-3-ethyl-2,3-dihydrobenzo[d]thiazole-6-carboxylate1173468-75-1C17H18N4O3S
- (Z)-N-(4,5-Dichloro-3-methylbenzo[d]thiazol-2(3H)-ylidene)-1,5-dimethyl-1H-pyrazole-3-carboxamide1013795-58-8C14H12Cl2N4OS
- N-(4,7-Dimethoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)-1,5-dimethyl-1H-pyrazole-3-carboxamide1020053-21-7C16H18N4O3S
- (Z)-N-(3-(2-Methoxyethyl)benzo[d]thiazol-2(3H)-ylidene)-1,5-dimethyl-1H-pyrazole-3-carboxamide1013810-53-1C16H18N4O2S
- [N(Z)]-N-[6-Bromo-3-(2-ethoxyethyl)-2(3H)-benzothiazolylidene]-1,5-dimethyl-1H-pyrazole-3-carboxamide1013769-31-7C17H19BrN4O2S
- (Z)-N-(4,6-Difluoro-3-(2-methoxyethyl)benzo[d]thiazol-2(3H)-ylidene)-1,5-dimethyl-1H-pyrazole-3-carboxamide1013771-61-3C16H16F2N4O2S
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