CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 23 atoms

45 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
45
With full pages
5
Scaffold SMILES

O=C(Nc1ncc(S(=O)(=O)c2ccccc2)s1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ncc(S(=O)(=O)c2ccccc2)s1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 45 of 45 chemicals

2-Bromo-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide chemical structure, C16H10BrN3O5S2, CAS 302548-44-3
2-Bromo-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide
CAS 302548-44-3C16H10BrN3O5S2
4-Methoxy-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide chemical structure, C17H13N3O6S2, CAS 302548-45-4
4-Methoxy-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide
CAS 302548-45-4C17H13N3O6S2
2-Methoxy-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide chemical structure, C17H13N3O6S2, CAS 302548-46-5
2-Methoxy-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide
CAS 302548-46-5C17H13N3O6S2
3,4,5-Trimethoxy-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide chemical structure, C19H17N3O8S2, CAS 302548-47-6
3,4,5-Trimethoxy-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide
CAS 302548-47-6C19H17N3O8S2
2,4-Dichloro-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide chemical structure, C16H9Cl2N3O5S2, CAS 302548-49-8
2,4-Dichloro-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide
CAS 302548-49-8C16H9Cl2N3O5S2
4-(tert-Butyl)-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide chemical structure, C20H19N3O5S2, CAS 302548-50-1
4-(tert-Butyl)-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide
CAS 302548-50-1C20H19N3O5S2
3,4-Dimethoxy-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}benzamide chemical structure, C18H15N3O7S2, CAS 292053-08-8
3,4-Dimethoxy-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}benzamide
CAS 292053-08-8C18H15N3O7S2
N-(5-((4-Nitrophenyl)sulfonyl)thiazol-2-yl)benzamide chemical structure, C16H11N3O5S2, CAS 302548-39-6
N-(5-((4-Nitrophenyl)sulfonyl)thiazol-2-yl)benzamide
CAS 302548-39-6C16H11N3O5S2
4-Chloro-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide chemical structure, C16H10ClN3O5S2, CAS 302548-40-9
4-Chloro-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide
CAS 302548-40-9C16H10ClN3O5S2
3-Chloro-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide chemical structure, C16H10ClN3O5S2, CAS 302548-41-0
3-Chloro-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide
CAS 302548-41-0C16H10ClN3O5S2
2-Chloro-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]benzamide chemical structure, C16H10ClN3O5S2, CAS 302548-42-1
2-Chloro-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]benzamide
CAS 302548-42-1C16H10ClN3O5S2
4-Bromo-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide chemical structure, C16H10BrN3O5S2, CAS 302548-43-2
4-Bromo-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide
CAS 302548-43-2C16H10BrN3O5S2
4-Ethoxy-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide chemical structure, C18H15N3O6S2, CAS 313469-83-9
4-Ethoxy-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide
CAS 313469-83-9C18H15N3O6S2
3-Bromo-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide chemical structure, C16H10BrN3O5S2, CAS 313469-80-6
3-Bromo-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide
CAS 313469-80-6C16H10BrN3O5S2
4-Fluoro-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide chemical structure, C16H10FN3O5S2, CAS 349612-49-3
4-Fluoro-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide
CAS 349612-49-3C16H10FN3O5S2
3,4-Diethoxy-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]benzamide chemical structure, C20H19N3O7S2, CAS 349438-63-7
3,4-Diethoxy-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]benzamide
CAS 349438-63-7C20H19N3O7S2
4-(N,N-Dimethylsulfamoyl)-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide chemical structure, C18H16N4O7S3, CAS 330201-85-9
4-(N,N-Dimethylsulfamoyl)-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide
CAS 330201-85-9C18H16N4O7S3
2-Fluoro-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide chemical structure, C16H10FN3O5S2, CAS 325720-29-4
2-Fluoro-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide
CAS 325720-29-4C16H10FN3O5S2
3-Nitro-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide chemical structure, C16H10N4O7S2, CAS 348132-64-9
3-Nitro-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide
CAS 348132-64-9C16H10N4O7S2
2,4-Dimethoxy-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]benzamide chemical structure, C18H15N3O7S2, CAS 349617-46-5
2,4-Dimethoxy-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]benzamide
CAS 349617-46-5C18H15N3O7S2
2-{[5-(4-Nitrobenzene-1-sulfonyl)-1,3-thiazol-2-yl]carbamoyl}benzoic acid chemical structure, C17H11N3O7S2, CAS 5788-78-3
2-{[5-(4-Nitrobenzene-1-sulfonyl)-1,3-thiazol-2-yl]carbamoyl}benzoic acid
CAS 5788-78-3C17H11N3O7S2
4-(N,N-Dipropylsulfamoyl)-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide chemical structure, C22H24N4O7S3, CAS 313469-85-1
4-(N,N-Dipropylsulfamoyl)-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide
CAS 313469-85-1C22H24N4O7S3
4-Butoxy-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide chemical structure, C20H19N3O6S2, CAS 313469-84-0
4-Butoxy-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide
CAS 313469-84-0C20H19N3O6S2
3-Fluoro-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide chemical structure, C16H10FN3O5S2, CAS 313395-88-9
3-Fluoro-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide
CAS 313395-88-9C16H10FN3O5S2