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Murcko scaffold

Ring system with 3 rings and 21 atoms

295 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
295
With full pages
9
Scaffold SMILES

O=C(Nc1ccccc1)c1cn(Cc2ccccc2)nn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1cn(Cc2ccccc2)nn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 295 chemicals

5-Amino-1-benzyl-N-phenyl-1H-1,2,3-triazole-4-carboxamide chemical structure, C16H15N5O, CAS 126537-91-5
5-Amino-1-benzyl-N-phenyl-1H-1,2,3-triazole-4-carboxamide
CAS 126537-91-5C16H15N5O
5-Amino-1-benzyl-N-(2-methoxyphenyl)-1H-1,2,3-triazole-4-carboxamide chemical structure, C17H17N5O2, CAS 361367-40-0
5-Amino-1-benzyl-N-(2-methoxyphenyl)-1H-1,2,3-triazole-4-carboxamide
CAS 361367-40-0C17H17N5O2
5-Amino-N-(4-methoxyphenyl)-1-(phenylmethyl)-1H-1,2,3-triazole-4-carboxamide chemical structure, C17H17N5O2, CAS 361367-39-7
5-Amino-N-(4-methoxyphenyl)-1-(phenylmethyl)-1H-1,2,3-triazole-4-carboxamide
CAS 361367-39-7C17H17N5O2
5-Amino-1-benzyl-N-(3,4-dimethylphenyl)-1H-1,2,3-triazole-4-carboxamide chemical structure, C18H19N5O, CAS 405279-24-5
5-Amino-1-benzyl-N-(3,4-dimethylphenyl)-1H-1,2,3-triazole-4-carboxamide
CAS 405279-24-5C18H19N5O
5-Amino-N-(4-chlorophenyl)-1-(4-methoxybenzyl)-1H-1,2,3-triazole-4-carboxamide chemical structure, C17H16ClN5O2, CAS 663929-75-7
5-Amino-N-(4-chlorophenyl)-1-(4-methoxybenzyl)-1H-1,2,3-triazole-4-carboxamide
CAS 663929-75-7C17H16ClN5O2
5-Amino-N-{4-[chloro(difluoro)methoxy]phenyl}-1-(4-methoxybenzyl)-1H-1,2,3-triazole-4-carboxamide chemical structure, C18H16ClF2N5O3, CAS 524036-00-8
5-Amino-N-{4-[chloro(difluoro)methoxy]phenyl}-1-(4-methoxybenzyl)-1H-1,2,3-triazole-4-carboxamide
CAS 524036-00-8C18H16ClF2N5O3
1H-1,2,3-Triazole-4-carboxamide, 5-amino-1-[(2-methoxyphenyl)methyl]-N-phenyl- chemical structure, C17H17N5O2, CAS 632291-71-5
1H-1,2,3-Triazole-4-carboxamide, 5-amino-1-[(2-methoxyphenyl)methyl]-N-phenyl-
CAS 632291-71-5C17H17N5O2
5-Amino-1-[(3-chlorophenyl)methyl]-N-(3-fluoro-4-methylphenyl)triazole-4-carboxamide chemical structure, C17H15ClFN5O, CAS 865655-96-5
5-Amino-1-[(3-chlorophenyl)methyl]-N-(3-fluoro-4-methylphenyl)triazole-4-carboxamide
CAS 865655-96-5C17H15ClFN5O
5-Amino-1-(3-chlorobenzyl)-N-(2,5-dimethylphenyl)-1H-1,2,3-triazole-4-carboxamide chemical structure, C18H18ClN5O, CAS 865655-97-6
5-Amino-1-(3-chlorobenzyl)-N-(2,5-dimethylphenyl)-1H-1,2,3-triazole-4-carboxamide
CAS 865655-97-6C18H18ClN5O
5-Amino-1-(3-chlorobenzyl)-N-(3,4-dimethylphenyl)-1H-1,2,3-triazole-4-carboxamide chemical structure, C18H18ClN5O, CAS 865655-98-7
5-Amino-1-(3-chlorobenzyl)-N-(3,4-dimethylphenyl)-1H-1,2,3-triazole-4-carboxamide
CAS 865655-98-7C18H18ClN5O
5-Amino-1-[(3-chlorophenyl)methyl]-N-(4-fluorophenyl)triazole-4-carboxamide chemical structure, C16H13ClFN5O, CAS 865656-00-4
5-Amino-1-[(3-chlorophenyl)methyl]-N-(4-fluorophenyl)triazole-4-carboxamide
CAS 865656-00-4C16H13ClFN5O
5-Amino-1-[(4-chlorophenyl)methyl]-N-(3-fluoro-4-methylphenyl)-1H-1,2,3-triazole-4-carboxamide chemical structure, C17H15ClFN5O, CAS 865656-01-5
5-Amino-1-[(4-chlorophenyl)methyl]-N-(3-fluoro-4-methylphenyl)-1H-1,2,3-triazole-4-carboxamide
CAS 865656-01-5C17H15ClFN5O
5-Amino-N-(4-bromophenyl)-1-[(4-chlorophenyl)methyl]triazole-4-carboxamide chemical structure, C16H13BrClN5O, CAS 865656-02-6
5-Amino-N-(4-bromophenyl)-1-[(4-chlorophenyl)methyl]triazole-4-carboxamide
CAS 865656-02-6C16H13BrClN5O
5-Amino-1-(4-chlorobenzyl)-N-(2,4-dimethoxyphenyl)-1H-1,2,3-triazole-4-carboxamide chemical structure, C18H18ClN5O3, CAS 865656-03-7
5-Amino-1-(4-chlorobenzyl)-N-(2,4-dimethoxyphenyl)-1H-1,2,3-triazole-4-carboxamide
CAS 865656-03-7C18H18ClN5O3
5-Amino-N-(2,4-dimethoxyphenyl)-1-[(3-fluorophenyl)methyl]-1H-1,2,3-triazole-4-carboxamide chemical structure, C18H18FN5O3, CAS 865656-16-2
5-Amino-N-(2,4-dimethoxyphenyl)-1-[(3-fluorophenyl)methyl]-1H-1,2,3-triazole-4-carboxamide
CAS 865656-16-2C18H18FN5O3
5-Amino-N-(5-chloro-2-methoxyphenyl)-1-{[3-(trifluoromethyl)phenyl]methyl}-1H-1,2,3-triazole-4-carboxamide chemical structure, C18H15ClF3N5O2, CAS 865656-22-0
5-Amino-N-(5-chloro-2-methoxyphenyl)-1-{[3-(trifluoromethyl)phenyl]methyl}-1H-1,2,3-triazole-4-carboxamide
CAS 865656-22-0C18H15ClF3N5O2
5-Amino-1-[(4-bromo-2-fluorophenyl)methyl]-N-(5-chloro-2-methoxyphenyl)-1H-1,2,3-triazole-4-carboxamide chemical structure, C17H14BrClFN5O2, CAS 866347-68-4
5-Amino-1-[(4-bromo-2-fluorophenyl)methyl]-N-(5-chloro-2-methoxyphenyl)-1H-1,2,3-triazole-4-carboxamide
CAS 866347-68-4C17H14BrClFN5O2
5-Amino-N-(5-chloro-2-methoxyphenyl)-1-(3-methoxybenzyl)-1H-1,2,3-triazole-4-carboxamide chemical structure, C18H18ClN5O3, CAS 866347-73-1
5-Amino-N-(5-chloro-2-methoxyphenyl)-1-(3-methoxybenzyl)-1H-1,2,3-triazole-4-carboxamide
CAS 866347-73-1C18H18ClN5O3
5-Amino-1-[(4-bromo-2-fluoro-phenyl)methyl]-N-(2,5-dimethoxyphenyl)triazole-4-carboxamide chemical structure, C18H17BrFN5O3, CAS 866347-75-3
5-Amino-1-[(4-bromo-2-fluoro-phenyl)methyl]-N-(2,5-dimethoxyphenyl)triazole-4-carboxamide
CAS 866347-75-3C18H17BrFN5O3
5-Amino-1-(4-bromo-2-fluorobenzyl)-N-(2-methoxy-5-methylphenyl)-1H-1,2,3-triazole-4-carboxamide chemical structure, C18H17BrFN5O2, CAS 866347-76-4
5-Amino-1-(4-bromo-2-fluorobenzyl)-N-(2-methoxy-5-methylphenyl)-1H-1,2,3-triazole-4-carboxamide
CAS 866347-76-4C18H17BrFN5O2
5-Amino-N-(2,5-dimethylphenyl)-1-(4-methylbenzyl)-1H-1,2,3-triazole-4-carboxamide chemical structure, C19H21N5O, CAS 902556-57-4
5-Amino-N-(2,5-dimethylphenyl)-1-(4-methylbenzyl)-1H-1,2,3-triazole-4-carboxamide
CAS 902556-57-4C19H21N5O
5-Amino-N-(2,3-dimethylphenyl)-1-(2-methylbenzyl)-1H-1,2,3-triazole-4-carboxamide chemical structure, C19H21N5O, CAS 902556-65-4
5-Amino-N-(2,3-dimethylphenyl)-1-(2-methylbenzyl)-1H-1,2,3-triazole-4-carboxamide
CAS 902556-65-4C19H21N5O
5-Amino-N-(2,3-dimethylphenyl)-1-(4-methylbenzyl)-1H-1,2,3-triazole-4-carboxamide chemical structure, C19H21N5O, CAS 902470-15-9
5-Amino-N-(2,3-dimethylphenyl)-1-(4-methylbenzyl)-1H-1,2,3-triazole-4-carboxamide
CAS 902470-15-9C19H21N5O
5-Amino-1-[(3-bromophenyl)methyl]-N-(3-methoxyphenyl)-1H-1,2,3-triazole-4-carboxamide chemical structure, C17H16BrN5O2, CAS 902471-30-1
5-Amino-1-[(3-bromophenyl)methyl]-N-(3-methoxyphenyl)-1H-1,2,3-triazole-4-carboxamide
CAS 902471-30-1C17H16BrN5O2