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Murcko scaffold

N-(5-Benzyl-1,3-thiazol-2-yl)benzamide scaffold

105 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
105
With full pages
24
Scaffold SMILES

O=C(Nc1ncc(Cc2ccccc2)s1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(5-Benzyl-1,3-thiazol-2-yl)benzamide page
Murcko scaffold O=C(Nc1ncc(Cc2ccccc2)s1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 105 chemicals

N-(5-(4-Methoxybenzyl)thiazol-2-yl)-4-methylbenzamide chemical structure, C19H18N2O2S, CAS 301176-78-3
N-(5-(4-Methoxybenzyl)thiazol-2-yl)-4-methylbenzamide
CAS 301176-78-3C19H18N2O2S
N-(5-Benzyl-1,3-thiazol-2-yl)benzamide chemical structure, C17H14N2OS, CAS 144836-54-4
N-(5-Benzyl-1,3-thiazol-2-yl)benzamide
CAS 144836-54-4C17H14N2OS
N-(5-Benzyl-1,3-thiazol-2-yl)-4-nitrobenzamide chemical structure, C17H13N3O3S, CAS 303791-89-1
N-(5-Benzyl-1,3-thiazol-2-yl)-4-nitrobenzamide
CAS 303791-89-1C17H13N3O3S
N-(5-Benzyl-1,3-thiazol-2-yl)-3-nitrobenzamide chemical structure, C17H13N3O3S, CAS 303791-90-4
N-(5-Benzyl-1,3-thiazol-2-yl)-3-nitrobenzamide
CAS 303791-90-4C17H13N3O3S
N-(5-Benzyl-1,3-thiazol-2-yl)-2-nitrobenzamide chemical structure, C17H13N3O3S, CAS 303791-91-5
N-(5-Benzyl-1,3-thiazol-2-yl)-2-nitrobenzamide
CAS 303791-91-5C17H13N3O3S
N-{5-[(2-Chlorophenyl)methyl]-1,3-thiazol-2-yl}benzamide chemical structure, C17H13ClN2OS, CAS 303791-93-7
N-{5-[(2-Chlorophenyl)methyl]-1,3-thiazol-2-yl}benzamide
CAS 303791-93-7C17H13ClN2OS
N-(5-Benzyl-1,3-thiazol-2-yl)-2-chlorobenzamide chemical structure, C17H13ClN2OS, CAS 5538-53-4
N-(5-Benzyl-1,3-thiazol-2-yl)-2-chlorobenzamide
CAS 5538-53-4C17H13ClN2OS
N-[5-(3-Methylbenzyl)-1,3-thiazol-2-yl]benzamide chemical structure, C18H16N2OS, CAS 303093-61-0
N-[5-(3-Methylbenzyl)-1,3-thiazol-2-yl]benzamide
CAS 303093-61-0C18H16N2OS
N-(5-(2-Chlorobenzyl)-1,3-thiazol-2-yl)-4-methylbenzamide chemical structure, C18H15ClN2OS, CAS 303093-73-4
N-(5-(2-Chlorobenzyl)-1,3-thiazol-2-yl)-4-methylbenzamide
CAS 303093-73-4C18H15ClN2OS
4-Methyl-N-[5-[(3-methylphenyl)methyl]-1,3-thiazol-2-yl]benzamide chemical structure, C19H18N2OS, CAS 304896-02-4
4-Methyl-N-[5-[(3-methylphenyl)methyl]-1,3-thiazol-2-yl]benzamide
CAS 304896-02-4C19H18N2OS
N-{5-[(4-Fluorophenyl)methyl]-1,3-thiazol-2-yl}-4-methylbenzamide chemical structure, C18H15FN2OS, CAS 292057-34-2
N-{5-[(4-Fluorophenyl)methyl]-1,3-thiazol-2-yl}-4-methylbenzamide
CAS 292057-34-2C18H15FN2OS
N-[5-[(4-Fluorophenyl)methyl]-1,3-thiazol-2-yl]benzamide chemical structure, C17H13FN2OS, CAS 301175-56-4
N-[5-[(4-Fluorophenyl)methyl]-1,3-thiazol-2-yl]benzamide
CAS 301175-56-4C17H13FN2OS
N-(5-(3-Nitrobenzyl)thiazol-2-yl)benzamide chemical structure, C17H13N3O3S, CAS 327078-01-3
N-(5-(3-Nitrobenzyl)thiazol-2-yl)benzamide
CAS 327078-01-3C17H13N3O3S
N-(5-Benzyl-1,3-thiazol-2-yl)-4-methylbenzamide chemical structure, C18H16N2OS, CAS 301176-88-5
N-(5-Benzyl-1,3-thiazol-2-yl)-4-methylbenzamide
CAS 301176-88-5C18H16N2OS
N-[5-(3-Chloro-4-methylbenzyl)-1,3-thiazol-2-yl]benzamide chemical structure, C18H15ClN2OS, CAS 501349-41-3
N-[5-(3-Chloro-4-methylbenzyl)-1,3-thiazol-2-yl]benzamide
CAS 501349-41-3C18H15ClN2OS
N-{5-[(4-Fluorophenyl)methyl]-1,3-thiazol-2-yl}-4-methoxybenzamide chemical structure, C18H15FN2O2S, CAS 638143-64-3
N-{5-[(4-Fluorophenyl)methyl]-1,3-thiazol-2-yl}-4-methoxybenzamide
CAS 638143-64-3C18H15FN2O2S
2-Chloro-N-(5-(4-fluorobenzyl)thiazol-2-yl)benzamide chemical structure, C17H12ClFN2OS, CAS 327061-99-4
2-Chloro-N-(5-(4-fluorobenzyl)thiazol-2-yl)benzamide
CAS 327061-99-4C17H12ClFN2OS
N-{5-[(4-Bromophenyl)methyl]-1,3-thiazol-2-yl}benzamide chemical structure, C17H13BrN2OS, CAS 304895-35-0
N-{5-[(4-Bromophenyl)methyl]-1,3-thiazol-2-yl}benzamide
CAS 304895-35-0C17H13BrN2OS
N-{5-[(4-Bromophenyl)methyl]-1,3-thiazol-2-YL}-2-chlorobenzamide chemical structure, C17H12BrClN2OS, CAS 292056-95-2
N-{5-[(4-Bromophenyl)methyl]-1,3-thiazol-2-YL}-2-chlorobenzamide
CAS 292056-95-2C17H12BrClN2OS
4-Chloro-N-{5-[(2,5-dichlorophenyl)methyl]-1,3-thiazol-2-yl}benzamide chemical structure, C17H11Cl3N2OS, CAS 302548-98-7
4-Chloro-N-{5-[(2,5-dichlorophenyl)methyl]-1,3-thiazol-2-yl}benzamide
CAS 302548-98-7C17H11Cl3N2OS
2-Chloro-N-[5-(2-chlorobenzyl)-1,3-thiazol-2-yl]benzamide chemical structure, C17H12Cl2N2OS, CAS 303792-33-8
2-Chloro-N-[5-(2-chlorobenzyl)-1,3-thiazol-2-yl]benzamide
CAS 303792-33-8C17H12Cl2N2OS
2-Chloro-N-[5-(4-chlorobenzyl)-1,3-thiazol-2-yl]benzamide chemical structure, C17H12Cl2N2OS, CAS 303792-34-9
2-Chloro-N-[5-(4-chlorobenzyl)-1,3-thiazol-2-yl]benzamide
CAS 303792-34-9C17H12Cl2N2OS
2-Chloro-N-[5-(3,4-dichlorobenzyl)-1,3-thiazol-2-yl]benzamide chemical structure, C17H11Cl3N2OS, CAS 304677-14-3
2-Chloro-N-[5-(3,4-dichlorobenzyl)-1,3-thiazol-2-yl]benzamide
CAS 304677-14-3C17H11Cl3N2OS
4-Chloro-N-(5-(2-chlorobenzyl)-1,3-thiazol-2-yl)benzamide chemical structure, C17H12Cl2N2OS, CAS 302548-96-5
4-Chloro-N-(5-(2-chlorobenzyl)-1,3-thiazol-2-yl)benzamide
CAS 302548-96-5C17H12Cl2N2OS