CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 23 atoms

28 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
28
With full pages
11
Scaffold SMILES

O=C(NN1C(=O)C(=Cc2ccccc2)SC1=S)c1ccncc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN1C(=O)C(=Cc2ccccc2)SC1=S)c1ccncc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 28 of 28 chemicals

4-Pyridinecarboxamide, N-(4-oxo-5-(phenylmethylene)-2-thioxo-3-thiazolidinyl)- chemical structure, C16H11N3O2S2, CAS 1908-94-7
4-Pyridinecarboxamide, N-(4-oxo-5-(phenylmethylene)-2-thioxo-3-thiazolidinyl)-
CAS 1908-94-7C16H11N3O2S2
N-[(5Z)-5-(4-Methylbenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]pyridine-4-carboxamide chemical structure, C17H13N3O2S2, CAS 301687-33-2
N-[(5Z)-5-(4-Methylbenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]pyridine-4-carboxamide
CAS 301687-33-2C17H13N3O2S2
N-[5-(3,4-Dimethoxybenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]isonicotinamide chemical structure, C18H15N3O4S2, CAS 301687-35-4
N-[5-(3,4-Dimethoxybenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]isonicotinamide
CAS 301687-35-4C18H15N3O4S2
4-Pyridinecarboxamide, N-(5-((4-methoxyphenyl)methylene)-4-oxo-2-thioxo-3-thiazolidinyl)- chemical structure, C17H13N3O3S2, CAS 68748-26-5
4-Pyridinecarboxamide, N-(5-((4-methoxyphenyl)methylene)-4-oxo-2-thioxo-3-thiazolidinyl)-
CAS 68748-26-5C17H13N3O3S2
4-Pyridinecarboxamide, N-(5-((4-(dimethylamino)phenyl)methylene)-4-oxo-2-thioxo-3-thiazolidinyl)- chemical structure, C18H16N4O2S2, CAS 1908-97-0
4-Pyridinecarboxamide, N-(5-((4-(dimethylamino)phenyl)methylene)-4-oxo-2-thioxo-3-thiazolidinyl)-
CAS 1908-97-0C18H16N4O2S2
N-[(5Z)-5-(2,6-Dichlorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]isonicotinamide chemical structure, C16H9Cl2N3O2S2, CAS 301687-38-7
N-[(5Z)-5-(2,6-Dichlorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]isonicotinamide
CAS 301687-38-7C16H9Cl2N3O2S2
N-[(5Z)-5-(3-Fluorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]pyridine-4-carboxamide chemical structure, C16H10FN3O2S2, CAS 301687-40-1
N-[(5Z)-5-(3-Fluorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]pyridine-4-carboxamide
CAS 301687-40-1C16H10FN3O2S2
N-[(5Z)-5-[(3-Methoxyphenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]pyridine-4-carboxamide chemical structure, C17H13N3O3S2, CAS 301687-34-3
N-[(5Z)-5-[(3-Methoxyphenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]pyridine-4-carboxamide
CAS 301687-34-3C17H13N3O3S2
N-[5-(4-Fluoro-benzylidene)-4-oxo-2-thioxo-thiazolidin-3-yl]-isonicotinamide chemical structure, C16H10FN3O2S2, CAS 301687-39-8
N-[5-(4-Fluoro-benzylidene)-4-oxo-2-thioxo-thiazolidin-3-yl]-isonicotinamide
CAS 301687-39-8C16H10FN3O2S2
4-Pyridinecarboxamide, N-(5-((3-hydroxyphenyl)methylene)-4-oxo-2-thioxo-3-thiazolidinyl)- chemical structure, C16H11N3O3S2, CAS 72732-38-8
4-Pyridinecarboxamide, N-(5-((3-hydroxyphenyl)methylene)-4-oxo-2-thioxo-3-thiazolidinyl)-
CAS 72732-38-8C16H11N3O3S2
N-[(5Z)-4-Oxo-2-thioxo-5-(3,4,5-trimethoxybenzylidene)-1,3-thiazolidin-3-yl]pyridine-4-carboxamide chemical structure, C19H17N3O5S2, CAS 301687-36-5
N-[(5Z)-4-Oxo-2-thioxo-5-(3,4,5-trimethoxybenzylidene)-1,3-thiazolidin-3-yl]pyridine-4-carboxamide
CAS 301687-36-5C19H17N3O5S2
4-Pyridinecarboxamide, N-(5-((2-chlorophenyl)methylene)-4-oxo-2-thioxo-3-thiazolidinyl)- chemical structure, C16H10ClN3O2S2, CAS 68710-98-5
4-Pyridinecarboxamide, N-(5-((2-chlorophenyl)methylene)-4-oxo-2-thioxo-3-thiazolidinyl)-
CAS 68710-98-5C16H10ClN3O2S2
N-[(5Z)-5-(2,4-Dichlorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]pyridine-4-carboxamide chemical structure, C16H9Cl2N3O2S2, CAS 301687-37-6
N-[(5Z)-5-(2,4-Dichlorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]pyridine-4-carboxamide
CAS 301687-37-6C16H9Cl2N3O2S2
N-{5-[(4-Bromophenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl}pyridine-4-carboxamide chemical structure, C16H10BrN3O2S2, CAS 6044-85-5
N-{5-[(4-Bromophenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl}pyridine-4-carboxamide
CAS 6044-85-5C16H10BrN3O2S2
N-[5-(4-Bromo-benzylidene)-4-oxo-2-thioxo-thiazolidin-3-yl]-isonicotinamide chemical structure, C16H10BrN3O2S2, CAS 301687-41-2
N-[5-(4-Bromo-benzylidene)-4-oxo-2-thioxo-thiazolidin-3-yl]-isonicotinamide
CAS 301687-41-2C16H10BrN3O2S2
N-[(5Z)-5-(2-Methoxybenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]pyridine-4-carboxamide chemical structure, C17H13N3O3S2, CAS 302811-71-8
N-[(5Z)-5-(2-Methoxybenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]pyridine-4-carboxamide
CAS 302811-71-8C17H13N3O3S2
4-Pyridinecarboxamide, N-(5-((4-hydroxy-3-methoxyphenyl)methylene)-4-oxo-2-thioxo-3-thiazolidinyl)- chemical structure, C17H13N3O4S2, CAS 72732-39-9
4-Pyridinecarboxamide, N-(5-((4-hydroxy-3-methoxyphenyl)methylene)-4-oxo-2-thioxo-3-thiazolidinyl)-
CAS 72732-39-9C17H13N3O4S2
N-[(5Z)-5-[(3-Ethoxy-4-hydroxyphenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]pyridine-4-carboxamide chemical structure, C18H15N3O4S2, CAS 438460-07-2
N-[(5Z)-5-[(3-Ethoxy-4-hydroxyphenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]pyridine-4-carboxamide
CAS 438460-07-2C18H15N3O4S2
N-[(5Z)-5-(2,4-Dimethoxybenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]pyridine-4-carboxamide chemical structure, C18H15N3O4S2, CAS 518349-20-7
N-[(5Z)-5-(2,4-Dimethoxybenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]pyridine-4-carboxamide
CAS 518349-20-7C18H15N3O4S2
4-Pyridinecarboxamide, N-(5-((4-chlorophenyl)methylene)-4-oxo-2-thioxo-3-thiazolidinyl)- chemical structure, C16H10ClN3O2S2, CAS 68710-99-6
4-Pyridinecarboxamide, N-(5-((4-chlorophenyl)methylene)-4-oxo-2-thioxo-3-thiazolidinyl)-
CAS 68710-99-6C16H10ClN3O2S2
N-[(5Z)-5-(3-Methoxy-4-propoxybenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]pyridine-4-carboxamide chemical structure, C20H19N3O4S2, CAS 292170-01-5
N-[(5Z)-5-(3-Methoxy-4-propoxybenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]pyridine-4-carboxamide
CAS 292170-01-5C20H19N3O4S2
N-[(5Z)-5-(4-Ethoxy-3-methoxybenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]pyridine-4-carboxamide chemical structure, C19H17N3O4S2, CAS 848993-08-8
N-[(5Z)-5-(4-Ethoxy-3-methoxybenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]pyridine-4-carboxamide
CAS 848993-08-8C19H17N3O4S2
4-Pyridinecarboxamide, N-(5-((2-nitrophenyl)methylene)-4-oxo-2-thioxo-3-thiazolidinyl)- chemical structure, C16H10N4O4S2, CAS 68711-00-2
4-Pyridinecarboxamide, N-(5-((2-nitrophenyl)methylene)-4-oxo-2-thioxo-3-thiazolidinyl)-
CAS 68711-00-2C16H10N4O4S2
4-Pyridinecarboxamide, N-(5-((2-hydroxyphenyl)methylene)-4-oxo-2-thioxo-3-thiazolidinyl)- chemical structure, C16H11N3O3S2, CAS 68710-95-2
4-Pyridinecarboxamide, N-(5-((2-hydroxyphenyl)methylene)-4-oxo-2-thioxo-3-thiazolidinyl)-
CAS 68710-95-2C16H11N3O3S2