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Murcko scaffold

Ring system with 2 rings and 15 atoms

84 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
84
With full pages
9
Scaffold SMILES

O=C(C=Cc1ccccc1)c1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccccc1)c1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 84 chemicals

2-[2,3-Dichloro-4-(3-oxo-3-thiophen-2-ylprop-1-enyl)phenoxy]acetic acid chemical structure, C15H10Cl2O4S, CAS 7235-54-3
2-[2,3-Dichloro-4-(3-oxo-3-thiophen-2-ylprop-1-enyl)phenoxy]acetic acid
CAS 7235-54-3C15H10Cl2O4S
2-Propen-1-one,3-(2-chlorophenyl)-1-(2-thienyl)- chemical structure, C13H9ClOS, CAS 74441-59-1
2-Propen-1-one,3-(2-chlorophenyl)-1-(2-thienyl)-
CAS 74441-59-1C13H9ClOS
1-(5-Chlorothiophen-2-yl)-3-(4-methoxyphenyl)prop-2-en-1-one chemical structure, C14H11ClO2S, CAS 152432-23-0
1-(5-Chlorothiophen-2-yl)-3-(4-methoxyphenyl)prop-2-en-1-one
CAS 152432-23-0C14H11ClO2S
3-(4-Chlorophenyl)-1-(2-thienyl)-2-propen-1-one chemical structure, C13H9ClOS, CAS 89144-98-9
3-(4-Chlorophenyl)-1-(2-thienyl)-2-propen-1-one
CAS 89144-98-9C13H9ClOS
3-(4-Chlorophenyl)-1-(5-chlorothiophen-2-yl)prop-2-en-1-one chemical structure, C13H8Cl2OS
3-(4-Chlorophenyl)-1-(5-chlorothiophen-2-yl)prop-2-en-1-one
C13H8Cl2OS
3-(2-Methoxyphenyl)-1-thiophen-2-ylprop-2-en-1-one chemical structure, C14H12O2S, CAS 74441-57-9
3-(2-Methoxyphenyl)-1-thiophen-2-ylprop-2-en-1-one
CAS 74441-57-9C14H12O2S
3-(4-Methoxyphenyl)-1-(thiophen-2-yl)prop-2-en-1-one chemical structure, C14H12O2S, CAS 89144-99-0
3-(4-Methoxyphenyl)-1-(thiophen-2-yl)prop-2-en-1-one
CAS 89144-99-0C14H12O2S
3-(3-Nitrophenyl)-1-(thiophen-2-yl)prop-2-en-1-one chemical structure, C13H9NO3S, CAS 13982-55-3
3-(3-Nitrophenyl)-1-(thiophen-2-yl)prop-2-en-1-one
CAS 13982-55-3C13H9NO3S
3-(2,5-Dimethoxyphenyl)-1-thiophen-2-ylprop-2-en-1-one chemical structure, C15H14O3S, CAS 364754-41-6
3-(2,5-Dimethoxyphenyl)-1-thiophen-2-ylprop-2-en-1-one
CAS 364754-41-6C15H14O3S
3-(2,4-Dimethoxyphenyl)-1-thiophen-2-ylprop-2-en-1-one chemical structure, C15H14O3S, CAS 18594-20-2
3-(2,4-Dimethoxyphenyl)-1-thiophen-2-ylprop-2-en-1-one
CAS 18594-20-2C15H14O3S
2-Propen-1-one, 1-(5-methyl-2-thienyl)-3-(4-nitrophenyl)- chemical structure, C14H11NO3S, CAS 58235-87-3
2-Propen-1-one, 1-(5-methyl-2-thienyl)-3-(4-nitrophenyl)-
CAS 58235-87-3C14H11NO3S
3-(3,4-Dimethoxyphenyl)-1-(2-thienyl)-2-propen-1-one chemical structure, C15H14O3S, CAS 74441-58-0
3-(3,4-Dimethoxyphenyl)-1-(2-thienyl)-2-propen-1-one
CAS 74441-58-0C15H14O3S
3-(4-Bromophenyl)-1-(thiophen-2-yl)prop-2-en-1-one chemical structure, C13H9BrOS, CAS 42292-00-2
3-(4-Bromophenyl)-1-(thiophen-2-yl)prop-2-en-1-one
CAS 42292-00-2C13H9BrOS
3-[2-(Difluoromethoxy)phenyl]-1-(thiophen-2-yl)prop-2-en-1-one chemical structure, C14H10F2O2S, CAS 5075-72-9
3-[2-(Difluoromethoxy)phenyl]-1-(thiophen-2-yl)prop-2-en-1-one
CAS 5075-72-9C14H10F2O2S
3-(3-Chlorophenyl)-1-thiophen-2-ylprop-2-en-1-one chemical structure, C13H9ClOS, CAS 18003-31-1
3-(3-Chlorophenyl)-1-thiophen-2-ylprop-2-en-1-one
CAS 18003-31-1C13H9ClOS
3-(4-Fluorophenyl)-1-(thiophen-2-yl)prop-2-en-1-one chemical structure, C13H9FOS, CAS 367-00-0
3-(4-Fluorophenyl)-1-(thiophen-2-yl)prop-2-en-1-one
CAS 367-00-0C13H9FOS
1-(5-Chlorothiophen-2-yl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one chemical structure, C15H13ClO3S, CAS 152432-25-2
1-(5-Chlorothiophen-2-yl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one
CAS 152432-25-2C15H13ClO3S
3-(4-Nitrophenyl)-1-(thiophen-2-yl)prop-2-en-1-one chemical structure, C13H9NO3S, CAS 6028-97-3
3-(4-Nitrophenyl)-1-(thiophen-2-yl)prop-2-en-1-one
CAS 6028-97-3C13H9NO3S
2-Propen-1-one, 1-(5-methoxy-2-thienyl)-3-(4-nitrophenyl)- chemical structure, C14H11NO4S, CAS 62913-89-7
2-Propen-1-one, 1-(5-methoxy-2-thienyl)-3-(4-nitrophenyl)-
CAS 62913-89-7C14H11NO4S
(2E)-3-(3,4-Dimethoxyphenyl)-1-(2-thienyl)-2-propen-1-one chemical structure, C15H14O3S, CAS 137444-52-1
(2E)-3-(3,4-Dimethoxyphenyl)-1-(2-thienyl)-2-propen-1-one
CAS 137444-52-1C15H14O3S
3-(4-Chlorophenyl)-1-(thiophen-2-yl)prop-2-en-1-one chemical structure, C13H9ClOS, CAS 79442-37-8
3-(4-Chlorophenyl)-1-(thiophen-2-yl)prop-2-en-1-one
CAS 79442-37-8C13H9ClOS
(2E)-3-(2,3-Dimethoxyphenyl)-1-(thiophen-2-yl)prop-2-en-1-one chemical structure, C15H14O3S, CAS 1403562-62-8
(2E)-3-(2,3-Dimethoxyphenyl)-1-(thiophen-2-yl)prop-2-en-1-one
CAS 1403562-62-8C15H14O3S
(2E)-3-(2-Methoxyphenyl)-1-(thiophen-2-yl)prop-2-en-1-one chemical structure, C14H12O2S, CAS 180298-05-9
(2E)-3-(2-Methoxyphenyl)-1-(thiophen-2-yl)prop-2-en-1-one
CAS 180298-05-9C14H12O2S
(E)-3-(4-Aminophenyl)-1-thiophen-2-ylprop-2-en-1-one chemical structure, C13H11NOS, CAS 1151741-40-0
(E)-3-(4-Aminophenyl)-1-thiophen-2-ylprop-2-en-1-one
CAS 1151741-40-0C13H11NOS