Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Ring system with 2 rings and 13 atoms

230 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 13
Chemicals: 230
With full pages: 38

Scaffold SMILES

S=C1NC=CC(c2ccccc2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold S=C1NC=CC(c2ccccc2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 192 of 230 chemicals

N,N-Diethyl-4-(4-fluorophenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide chemical structure, C16H20FN3OS, CAS 634171-56-5

N,N-Diethyl-4-(4-fluorophenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide

CAS 634171-56-5C₁₆H₂₀FN₃OS

Ethyl [4-(5-acetyl-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidin-4-yl)-2-ethoxy-6-iodophenoxy]acetate chemical structure, C19H23IN2O5S, CAS 713103-52-7

Ethyl [4-(5-acetyl-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidin-4-yl)-2-ethoxy-6-iodophenoxy]acetate

CAS 713103-52-7C₁₉H₂₃IN₂O₅S

Ethyl 4-(2-ethoxy-5-nitrophenyl)-6-propyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate chemical structure, C18H23N3O5S, CAS 713104-23-5

Ethyl 4-(2-ethoxy-5-nitrophenyl)-6-propyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate

CAS 713104-23-5C₁₈H₂₃N₃O₅S

Ethyl 6-methyl-2-sulfanylidene-4-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-pyrimidine-5-carboxylate chemical structure, C15H15F3N2O2S, CAS 394226-76-7

Ethyl 6-methyl-2-sulfanylidene-4-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-pyrimidine-5-carboxylate

CAS 394226-76-7C₁₅H₁₅F₃N₂O₂S

Ethyl 6-methyl-4-(3-methylphenyl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate chemical structure, C15H18N2O2S, CAS 113697-58-8

Ethyl 6-methyl-4-(3-methylphenyl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate

CAS 113697-58-8C₁₅H₁₈N₂O₂S

(±)-Monastrol chemical structure, C14H16N2O3S, CAS 329689-23-8

CAS 329689-23-8C₁₄H₁₆N₂O₃S

Ethyl 4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate chemical structure, C15H18N2O4S, CAS 5948-75-4

Ethyl 4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate

CAS 5948-75-4C₁₅H₁₈N₂O₄S

Pentyl 4-(2,5-dimethoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C19H26N2O4S, CAS 296262-61-8

Pentyl 4-(2,5-dimethoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

CAS 296262-61-8C₁₉H₂₆N₂O₄S

Butyl 4-(2-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C17H22N2O3S, CAS 300799-46-6

Butyl 4-(2-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

CAS 300799-46-6C₁₇H₂₂N₂O₃S

3,4-Dimethyl-6-phenyl-2-sulfanylidene-1,6-dihydropyrimidine-5-carboxylic acid propan-2-yl ester chemical structure, C16H20N2O2S, CAS 300383-47-5

3,4-Dimethyl-6-phenyl-2-sulfanylidene-1,6-dihydropyrimidine-5-carboxylic acid propan-2-yl ester

CAS 300383-47-5C₁₆H₂₀N₂O₂S

2-Ethylsulfanylethyl 4-(2,5-dimethoxyphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate chemical structure, C18H24N2O4S2, CAS 296262-98-1

2-Ethylsulfanylethyl 4-(2,5-dimethoxyphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate

CAS 296262-98-1C₁₈H₂₄N₂O₄S₂

2-Methylpropyl 4-[2-(ethyloxy)phenyl]-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C18H24N2O3S, CAS 302561-45-1

2-Methylpropyl 4-[2-(ethyloxy)phenyl]-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

CAS 302561-45-1C₁₈H₂₄N₂O₃S

Hexyl 6-methyl-4-(2-propoxyphenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C21H30N2O3S, CAS 295344-42-2

Hexyl 6-methyl-4-(2-propoxyphenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

CAS 295344-42-2C₂₁H₃₀N₂O₃S

Hexyl 4-(2-ethoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C20H28N2O3S, CAS 295344-02-4

Hexyl 4-(2-ethoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

CAS 295344-02-4C₂₀H₂₈N₂O₃S

Methyl 1,2,3,4-tetrahydro-4-(3-hydroxy-4-nitrophenyl)-6-methyl-2-thioxo-5-pyrimidinecarboxylate chemical structure, C13H13N3O5S, CAS 304448-93-9

Methyl 1,2,3,4-tetrahydro-4-(3-hydroxy-4-nitrophenyl)-6-methyl-2-thioxo-5-pyrimidinecarboxylate

CAS 304448-93-9C₁₃H₁₃N₃O₅S

Ethyl 4-[4-(dimethylamino)phenyl]-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C16H21N3O2S, CAS 19492-61-6

Ethyl 4-[4-(dimethylamino)phenyl]-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

CAS 19492-61-6C₁₆H₂₁N₃O₂S

Ethyl 1-acetyl-6-(2-fluorophenyl)-1,2,3,6-tetrahydro-4-methyl-2-thioxo-5-pyrimidinecarboxylate chemical structure, C16H17FN2O3S, CAS 313391-67-2

Ethyl 1-acetyl-6-(2-fluorophenyl)-1,2,3,6-tetrahydro-4-methyl-2-thioxo-5-pyrimidinecarboxylate

CAS 313391-67-2C₁₆H₁₇FN₂O₃S

ET 3-AC-6-ME-4-(3-Nitro-PH)-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate chemical structure, C16H17N3O5S, CAS 111535-63-8

ET 3-AC-6-ME-4-(3-Nitro-PH)-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

CAS 111535-63-8C₁₆H₁₇N₃O₅S

Ethyl 3-acetyl-4-(3,4-dimethoxyphenyl)-6-methyl-2-sulfanylidene-1,4-dihydropyrimidine-5-carboxylate chemical structure, C18H22N2O5S, CAS 330567-77-6

Ethyl 3-acetyl-4-(3,4-dimethoxyphenyl)-6-methyl-2-sulfanylidene-1,4-dihydropyrimidine-5-carboxylate

CAS 330567-77-6C₁₈H₂₂N₂O₅S

Methyl 3-acetyl-4-(4-methoxyphenyl)-6-methyl-2-sulfanylidene-1,4-dihydropyrimidine-5-carboxylate chemical structure, C16H18N2O4S, CAS 330567-78-7

Methyl 3-acetyl-4-(4-methoxyphenyl)-6-methyl-2-sulfanylidene-1,4-dihydropyrimidine-5-carboxylate

CAS 330567-78-7C₁₆H₁₈N₂O₄S

1-[4-(4-Methoxyphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidin-5-yl]ethanone chemical structure, C14H16N2O2S, CAS 219806-93-6

1-[4-(4-Methoxyphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidin-5-yl]ethanone

CAS 219806-93-6C₁₄H₁₆N₂O₂S

Allyl 4-(2,5-dimethoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate chemical structure, C17H20N2O4S, CAS 299406-82-9

Allyl 4-(2,5-dimethoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

CAS 299406-82-9C₁₇H₂₀N₂O₄S

Ethyl 4-(4-(diethylamino)phenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C18H25N3O2S, CAS 331235-65-5

Ethyl 4-(4-(diethylamino)phenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

CAS 331235-65-5C₁₈H₂₅N₃O₂S

Ethyl 4-(2,3-dimethoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C16H20N2O4S, CAS 313533-44-7

Ethyl 4-(2,3-dimethoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

CAS 313533-44-7C₁₆H₂₀N₂O₄S