Murcko scaffold
Ring system with 2 rings and 16 atoms
16 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 16
- Chemicals
- 16
- With full pages
- 5
Scaffold SMILES
O=C(NN=Cc1ccc[nH]1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold O=C(NN=Cc1ccc[nH]1)c1ccccc1](/scaffold/DZJKGHIDQIMCMH-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 16 of 16 chemicals
3-Iodo-4-methoxy-N-(1H-pyrrol-2-ylmethylideneamino)benzamide
C13H12IN3O2
![N-[(E)-(1-Methylpyrrol-2-yl)methylideneamino]-3-(1,1,2,2-tetrafluoroethoxy)benzamide chemical structure, C15H13F4N3O2, CAS 445001-13-8](/s/CLXAWVRIGWFTGS-AWQFTUOYSA-N.svg)
N-[(E)-(1-Methylpyrrol-2-yl)methylideneamino]-3-(1,1,2,2-tetrafluoroethoxy)benzamide
CAS 445001-13-8C15H13F4N3O2
![2-Hydroxy-N-[(E)-(1-methylpyrrol-2-yl)methylideneamino]-3,5-di(propan-2-yl)benzamide chemical structure, C19H25N3O2, CAS 445259-15-4](/s/XYTVKUNLYMSXFS-RGVLZGJSSA-N.svg)
2-Hydroxy-N-[(E)-(1-methylpyrrol-2-yl)methylideneamino]-3,5-di(propan-2-yl)benzamide
CAS 445259-15-4C19H25N3O2
3-Methyl-N'-(1H-pyrrol-2-ylmethylene)benzohydrazide
CAS 1164457-91-3C13H13N3O
Benzoic acid, 2-hydroxy-, (1H-pyrrol-2-ylmethylene)hydrazide
CAS 19015-16-8C12H11N3O2
2-Nitro-N'-(1H-pyrrol-2-ylmethylene)benzohydrazide
CAS 314279-82-8C12H10N4O3
3-Chloro-N'-(1H-pyrrol-2-ylmethylene)benzohydrazide
CAS 93418-23-6C12H10ClN3O
Benzoic acid, 3-nitro-, (1H-pyrrol-2-ylmethylene)hydrazide
CAS 119034-11-6C12H10N4O3
Benzoic acid, (1H-pyrrol-2-ylmethylene)hydrazide
CAS 10344-26-0C12H11N3O
4-Nitro-N'-(1H-pyrrol-2-ylmethylene)benzohydrazide
CAS 181209-10-9C12H10N4O3
![3-Fluoro-N'-[(E)-1H-pyrrol-2-ylmethylidene]benzohydrazide chemical structure, C12H10FN3O, CAS 93418-20-3](/s/HMRNTMBABXMHSB-OVCLIPMQSA-N.svg)
3-Fluoro-N'-[(E)-1H-pyrrol-2-ylmethylidene]benzohydrazide
CAS 93418-20-3C12H10FN3O
Pyrrole aldehyde phenyl semicarbazone
CAS 113906-09-5C13H13N3O2
3-Iodo-4-methoxy-N'-(1H-pyrrol-2-ylmethylene)benzohydrazide
CAS 5836-61-3C13H12IN3O2
Tin, dichlorodiethyl((2-hydroxybenzoic acid-kappaO) (1H-pyrrol-2-ylmethylene)hydrazide-kappaN2)-, (OC-6-32)-
CAS 201009-56-5C16H21Cl2N3O2Sn
Tin, dibutyldichloro((2-hydroxybenzoic acid-kappaO) (1H-pyrrol-2-ylmethylene)hydrazide-kappaN2)-, (OC-6-32)-
CAS 201009-57-6C20H29Cl2N3O2Sn
Tin, dichloro((2-hydroxybenzoic acid-kappaO) (1H-pyrrol-2-ylmethylene)hydrazide-kappaN2)diphenyl-, (OC-6-32)-
CAS 201009-58-7C24H21Cl2N3O2Sn
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold O=C(CSc1nnc[nH]1)Nc1ccccc1](/scaffold/VJBDIQRNSVRUDP-UHFFFAOYSA-N/structure.svg)
O=C(CSc1nnc[nH]1)Nc1ccccc165 chemicals
O=C(COc1ccccc1)Nc1nccs143 chemicals
O=C(CCc1ccco1)Nc1ccccc134 chemicals
O=C(CSc1nncs1)Nc1ccccc134 chemicals![Scaffold O=C(NN=Cc1ccccc1)c1cc[nH]n1](/scaffold/UEBQXDJERRSAMF-UHFFFAOYSA-N/structure.svg)
O=C(NN=Cc1ccccc1)c1cc[nH]n129 chemicals
O=C(CCc1ccccc1)Nc1nncs125 chemicals
S=C(NCc1ccco1)Nc1ccccc124 chemicals![Scaffold O=C(CSc1nnn[nH]1)Nc1ccccc1](/scaffold/FDRBWKCIVMSABC-UHFFFAOYSA-N/structure.svg)
O=C(CSc1nnn[nH]1)Nc1ccccc122 chemicals![Scaffold O=C(CSc1ncc[nH]1)Nc1ccccc1](/scaffold/OMOYRSCPUXAYDW-UHFFFAOYSA-N/structure.svg)
O=C(CSc1ncc[nH]1)Nc1ccccc121 chemicals
O=C(NC(=S)Nc1ccccc1)c1ccco121 chemicals
O=C(CCN1CCCC1)Nc1ccccc120 chemicals
O=C(NN=Cc1ccco1)c1ccccc119 chemicals