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Murcko scaffold

2(1H)-Isoquinolinecarbothioamide, 3,4-dihydro-N-phenyl- scaffold

34 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
34
With full pages
12
Scaffold SMILES

S=C(Nc1ccccc1)N1CCc2ccccc2C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2(1H)-Isoquinolinecarbothioamide, 3,4-dihydro-N-phenyl- page
Murcko scaffold S=C(Nc1ccccc1)N1CCc2ccccc2C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 34 of 34 chemicals

N-(3-(Trifluoromethyl)phenyl)-3,4-dihydroisoquinoline-2(1H)-carbothioamide chemical structure, C17H15F3N2S, CAS 216774-42-4
N-(3-(Trifluoromethyl)phenyl)-3,4-dihydroisoquinoline-2(1H)-carbothioamide
CAS 216774-42-4C17H15F3N2S
N-(2-Chlorophenyl)-3,4-dihydroisoquinoline-2(1H)-carbothioamide chemical structure, C16H15ClN2S, CAS 216774-62-8
N-(2-Chlorophenyl)-3,4-dihydroisoquinoline-2(1H)-carbothioamide
CAS 216774-62-8C16H15ClN2S
4-[(3,4-Dihydro-1H-isoquinoline-2-carbothioyl)-amino]-benzoic acid ethyl ester chemical structure, C19H20N2O2S, CAS 351060-66-7
4-[(3,4-Dihydro-1H-isoquinoline-2-carbothioyl)-amino]-benzoic acid ethyl ester
CAS 351060-66-7C19H20N2O2S
2(1H)-Isoquinolinecarbothioamide, 3,4-dihydro-N-phenyl- chemical structure, C16H16N2S, CAS 89652-23-3
2(1H)-Isoquinolinecarbothioamide, 3,4-dihydro-N-phenyl-
CAS 89652-23-3C16H16N2S
6,7-Dimethoxy-N-phenyl-3,4-dihydroisoquinoline-2(1H)-carbothioamide chemical structure, C18H20N2O2S, CAS 332032-79-8
6,7-Dimethoxy-N-phenyl-3,4-dihydroisoquinoline-2(1H)-carbothioamide
CAS 332032-79-8C18H20N2O2S
N-(4-Methylphenyl)-3,4-dihydroisoquinoline-2(1H)-carbothioamide chemical structure, C17H18N2S, CAS 438010-29-8
N-(4-Methylphenyl)-3,4-dihydroisoquinoline-2(1H)-carbothioamide
CAS 438010-29-8C17H18N2S
N-(4-Methoxyphenyl)-3,4-dihydro-1H-isoquinoline-2-carbothioamide chemical structure, C17H18N2OS, CAS 502868-57-7
N-(4-Methoxyphenyl)-3,4-dihydro-1H-isoquinoline-2-carbothioamide
CAS 502868-57-7C17H18N2OS
Methyl 4-[(3,4-dihydroisoquinolin-2(1H)-ylcarbonothioyl)amino]benzoate chemical structure, C18H18N2O2S, CAS 461457-10-3
Methyl 4-[(3,4-dihydroisoquinolin-2(1H)-ylcarbonothioyl)amino]benzoate
CAS 461457-10-3C18H18N2O2S
N-(4-Fluorophenyl)-3,4-dihydroisoquinoline-2(1H)-carbothioamide chemical structure, C16H15FN2S, CAS 406927-45-5
N-(4-Fluorophenyl)-3,4-dihydroisoquinoline-2(1H)-carbothioamide
CAS 406927-45-5C16H15FN2S
N-(2,5-Dimethoxyphenyl)-3,4-dihydro-2(1H)-isoquinolinecarbothioamide chemical structure, C18H20N2O2S, CAS 664969-18-0
N-(2,5-Dimethoxyphenyl)-3,4-dihydro-2(1H)-isoquinolinecarbothioamide
CAS 664969-18-0C18H20N2O2S
N-(2,4-Dimethoxyphenyl)-3,4-dihydroisoquinoline-2(1H)-carbothioamide chemical structure, C18H20N2O2S, CAS 664969-17-9
N-(2,4-Dimethoxyphenyl)-3,4-dihydroisoquinoline-2(1H)-carbothioamide
CAS 664969-17-9C18H20N2O2S
N-(3,5-Dimethylphenyl)-3,4-dihydro-1H-isoquinoline-2-carbothioamide chemical structure, C18H20N2S, CAS 482292-26-2
N-(3,5-Dimethylphenyl)-3,4-dihydro-1H-isoquinoline-2-carbothioamide
CAS 482292-26-2C18H20N2S
N-(3-Chloro-2-methylphenyl)-3,4-dihydro-2(1H)-isoquinolinecarbothioamide chemical structure, C17H17ClN2S, CAS 693233-53-3
N-(3-Chloro-2-methylphenyl)-3,4-dihydro-2(1H)-isoquinolinecarbothioamide
CAS 693233-53-3C17H17ClN2S
N-(3,5-Dimethoxyphenyl)-3,4-dihydroisoquinoline-2(1H)-carbothioamide chemical structure, C18H20N2O2S, CAS 664969-19-1
N-(3,5-Dimethoxyphenyl)-3,4-dihydroisoquinoline-2(1H)-carbothioamide
CAS 664969-19-1C18H20N2O2S
Methyl {4-[(3,4-dihydroisoquinolin-2(1H)-ylcarbonothioyl)amino]phenyl}acetate chemical structure, C19H20N2O2S, CAS 516458-58-5
Methyl {4-[(3,4-dihydroisoquinolin-2(1H)-ylcarbonothioyl)amino]phenyl}acetate
CAS 516458-58-5C19H20N2O2S
N-(2-Methoxyphenyl)-3,4-dihydroisoquinoline-2(1H)-carbothioamide chemical structure, C17H18N2OS, CAS 406925-60-8
N-(2-Methoxyphenyl)-3,4-dihydroisoquinoline-2(1H)-carbothioamide
CAS 406925-60-8C17H18N2OS
N-(3,4-Dimethoxyphenyl)-3,4-dihydro-1H-isoquinoline-2-carbothioamide chemical structure, C18H20N2O2S, CAS 708221-63-0
N-(3,4-Dimethoxyphenyl)-3,4-dihydro-1H-isoquinoline-2-carbothioamide
CAS 708221-63-0C18H20N2O2S
N-(3-Nitrophenyl)-3,4-dihydro-1H-isoquinoline-2-carbothioamide chemical structure, C16H15N3O2S, CAS 708228-72-2
N-(3-Nitrophenyl)-3,4-dihydro-1H-isoquinoline-2-carbothioamide
CAS 708228-72-2C16H15N3O2S
N-(2-(Trifluoromethyl)phenyl)-3,4-dihydroisoquinoline-2(1H)-carbothioamide chemical structure, C17H15F3N2S, CAS 575493-14-0
N-(2-(Trifluoromethyl)phenyl)-3,4-dihydroisoquinoline-2(1H)-carbothioamide
CAS 575493-14-0C17H15F3N2S
N-(5-Chloro-2-methoxyphenyl)-3,4-dihydroisoquinoline-2(1H)-carbothioamide chemical structure, C17H17ClN2OS, CAS 690247-65-5
N-(5-Chloro-2-methoxyphenyl)-3,4-dihydroisoquinoline-2(1H)-carbothioamide
CAS 690247-65-5C17H17ClN2OS
N-(3-Chloro-4-fluorophenyl)-3,4-dihydro-1H-isoquinoline-2-carbothioamide chemical structure, C16H14ClFN2S, CAS 708243-12-3
N-(3-Chloro-4-fluorophenyl)-3,4-dihydro-1H-isoquinoline-2-carbothioamide
CAS 708243-12-3C16H14ClFN2S
N-(4-Acetylphenyl)-3,4-dihydro-1H-isoquinoline-2-carbothioamide chemical structure, C18H18N2OS, CAS 637325-86-1
N-(4-Acetylphenyl)-3,4-dihydro-1H-isoquinoline-2-carbothioamide
CAS 637325-86-1C18H18N2OS
Dimethyl 2-[(3,4-dihydroisoquinolin-2(1H)-ylcarbonothioyl)amino]terephthalate chemical structure, C20H20N2O4S, CAS 717830-21-2
Dimethyl 2-[(3,4-dihydroisoquinolin-2(1H)-ylcarbonothioyl)amino]terephthalate
CAS 717830-21-2C20H20N2O4S
6,7-Dimethoxy-N-(3-methoxyphenyl)-3,4-dihydroisoquinoline-2(1H)-carbothioamide chemical structure, C19H22N2O3S, CAS 883952-57-6
6,7-Dimethoxy-N-(3-methoxyphenyl)-3,4-dihydroisoquinoline-2(1H)-carbothioamide
CAS 883952-57-6C19H22N2O3S