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Murcko scaffold

Ring system with 2 rings and 17 atoms

10 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
10
With full pages
8
Scaffold SMILES

O=C(COC(=O)c1cccnc1)c1cc[nH]c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COC(=O)c1cccnc1)c1cc[nH]c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

[2-Oxo-2-(1,2,5-trimethylpyrrol-3-yl)ethyl] 2-chloropyridine-3-carboxylate chemical structure, C15H15ClN2O3, CAS 744235-35-6
[2-Oxo-2-(1,2,5-trimethylpyrrol-3-yl)ethyl] 2-chloropyridine-3-carboxylate
CAS 744235-35-6C15H15ClN2O3
[2-Oxo-2-(1,2,5-trimethylpyrrol-3-yl)ethyl] 2-methylsulfanylpyridine-3-carboxylate chemical structure, C16H18N2O3S, CAS 744241-68-7
[2-Oxo-2-(1,2,5-trimethylpyrrol-3-yl)ethyl] 2-methylsulfanylpyridine-3-carboxylate
CAS 744241-68-7C16H18N2O3S
2-[4-(Ethoxycarbonyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-oxoethyl 6-chloropyridine-3-carboxylate chemical structure, C17H17ClN2O5, CAS 730982-51-1
2-[4-(Ethoxycarbonyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-oxoethyl 6-chloropyridine-3-carboxylate
CAS 730982-51-1C17H17ClN2O5
[2-[1-(2-Methoxyethyl)-2,5-dimethylpyrrol-3-yl]-2-oxoethyl] 2-methylsulfanylpyridine-3-carboxylate chemical structure, C18H22N2O4S, CAS 852545-48-3
[2-[1-(2-Methoxyethyl)-2,5-dimethylpyrrol-3-yl]-2-oxoethyl] 2-methylsulfanylpyridine-3-carboxylate
CAS 852545-48-3C18H22N2O4S
[2-[1-(1-Methoxypropan-2-yl)-2,5-dimethylpyrrol-3-yl]-2-oxoethyl] 5,6-dichloropyridine-3-carboxylate chemical structure, C18H20Cl2N2O4, CAS 731837-61-9
[2-[1-(1-Methoxypropan-2-yl)-2,5-dimethylpyrrol-3-yl]-2-oxoethyl] 5,6-dichloropyridine-3-carboxylate
CAS 731837-61-9C18H20Cl2N2O4
2-(4-(Ethoxycarbonyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-oxoethyl 2-(methylthio)nicotinate chemical structure, C18H20N2O5S, CAS 852465-39-5
2-(4-(Ethoxycarbonyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-oxoethyl 2-(methylthio)nicotinate
CAS 852465-39-5C18H20N2O5S
2-[4-(Ethoxycarbonyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-oxoethyl 2-chloropyridine-3-carboxylate chemical structure, C17H17ClN2O5, CAS 852545-54-1
2-[4-(Ethoxycarbonyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-oxoethyl 2-chloropyridine-3-carboxylate
CAS 852545-54-1C17H17ClN2O5
2-[2,5-Dimethyl-1-(2,2,2-trifluoroethyl)-1H-pyrrol-3-yl]-2-oxoethyl 6-chloropyridine-3-carboxylate chemical structure, C16H14ClF3N2O3, CAS 848834-95-7
2-[2,5-Dimethyl-1-(2,2,2-trifluoroethyl)-1H-pyrrol-3-yl]-2-oxoethyl 6-chloropyridine-3-carboxylate
CAS 848834-95-7C16H14ClF3N2O3
[2-(1-Ethyl-2,5-dimethylpyrrol-3-yl)-2-oxoethyl] 2-methylsulfanylpyridine-3-carboxylate chemical structure, C17H20N2O3S, CAS 877043-38-4
[2-(1-Ethyl-2,5-dimethylpyrrol-3-yl)-2-oxoethyl] 2-methylsulfanylpyridine-3-carboxylate
CAS 877043-38-4C17H20N2O3S
2-[2,5-Dimethyl-1-(propan-2-yl)-1H-pyrrol-3-yl]-2-oxoethyl 2,6-dichloropyridine-3-carboxylate chemical structure, C17H18Cl2N2O3, CAS 1444152-31-1
2-[2,5-Dimethyl-1-(propan-2-yl)-1H-pyrrol-3-yl]-2-oxoethyl 2,6-dichloropyridine-3-carboxylate
CAS 1444152-31-1C17H18Cl2N2O3