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Murcko scaffold

Ring system with 3 rings and 20 atoms

23 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
23
With full pages
13
Scaffold SMILES

O=S(=O)(Nc1ccc2c(c1)OCCO2)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(Nc1ccc2c(c1)OCCO2)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 23 of 23 chemicals

N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-4-methoxybenzenesulfonamide chemical structure, C15H15NO5S, CAS 97618-46-7
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-4-methoxybenzenesulfonamide
CAS 97618-46-7C15H15NO5S
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-4-fluorobenzenesulfonamide chemical structure, C14H12FNO4S, CAS 329043-48-3
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-4-fluorobenzenesulfonamide
CAS 329043-48-3C14H12FNO4S
4-Chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)benzenesulfonamide chemical structure, C14H12ClNO4S, CAS 96984-93-9
4-Chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)benzenesulfonamide
CAS 96984-93-9C14H12ClNO4S
N-[4-(2,3-Dihydro-1,4-benzodioxin-6-ylsulfamoyl)phenyl]acetamide chemical structure, C16H16N2O5S, CAS 462619-75-6
N-[4-(2,3-Dihydro-1,4-benzodioxin-6-ylsulfamoyl)phenyl]acetamide
CAS 462619-75-6C16H16N2O5S
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-nitrobenzenesulfonamide chemical structure, C14H12N2O6S, CAS 424812-21-5
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-nitrobenzenesulfonamide
CAS 424812-21-5C14H12N2O6S
4-tert-Butyl-N-(2,3-dihydro-1,4-benzodioxin-6-yl)benzenesulfonamide chemical structure, C18H21NO4S, CAS 379247-97-9
4-tert-Butyl-N-(2,3-dihydro-1,4-benzodioxin-6-yl)benzenesulfonamide
CAS 379247-97-9C18H21NO4S
3-Chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)benzenesulfonamide chemical structure, C14H12ClNO4S, CAS 667913-31-7
3-Chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)benzenesulfonamide
CAS 667913-31-7C14H12ClNO4S
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-methoxybenzenesulfonamide chemical structure, C15H15NO5S, CAS 667913-33-9
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-methoxybenzenesulfonamide
CAS 667913-33-9C15H15NO5S
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-fluorobenzenesulfonamide chemical structure, C14H12FNO4S, CAS 667913-34-0
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-fluorobenzenesulfonamide
CAS 667913-34-0C14H12FNO4S
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-methylbenzenesulfonamide chemical structure, C15H15NO4S, CAS 667913-32-8
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-methylbenzenesulfonamide
CAS 667913-32-8C15H15NO4S
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-N-(phenylsulfonyl)glycine chemical structure, C16H15NO6S, CAS 361472-41-5
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-N-(phenylsulfonyl)glycine
CAS 361472-41-5C16H15NO6S
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-4-methoxy-3-methylbenzenesulfonamide chemical structure, C16H17NO5S, CAS 641998-70-1
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-4-methoxy-3-methylbenzenesulfonamide
CAS 641998-70-1C16H17NO5S
2,3-Dichloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-methoxybenzenesulfonamide chemical structure, C15H13Cl2NO5S, CAS 643003-18-3
2,3-Dichloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-methoxybenzenesulfonamide
CAS 643003-18-3C15H13Cl2NO5S
Methyl N-(2,3-dihydro-1,4-benzodioxin-6-yl)-N-(phenylsulfonyl)glycinate chemical structure, C17H17NO6S, CAS 713112-11-9
Methyl N-(2,3-dihydro-1,4-benzodioxin-6-yl)-N-(phenylsulfonyl)glycinate
CAS 713112-11-9C17H17NO6S
3-Chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-methoxybenzenesulfonamide chemical structure, C15H14ClNO5S, CAS 712295-28-8
3-Chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-methoxybenzenesulfonamide
CAS 712295-28-8C15H14ClNO5S
N-(7-Acetyl-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-4-methylbenzenesulfonamide chemical structure, C17H17NO5S, CAS 713502-14-8
N-(7-Acetyl-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-4-methylbenzenesulfonamide
CAS 713502-14-8C17H17NO5S
2,6-Dichloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)benzenesulfonamide chemical structure, C14H11Cl2NO4S, CAS 613658-47-2
2,6-Dichloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)benzenesulfonamide
CAS 613658-47-2C14H11Cl2NO4S
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3,4-dimethylbenzenesulfonamide chemical structure, C16H17NO4S, CAS 379248-04-1
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3,4-dimethylbenzenesulfonamide
CAS 379248-04-1C16H17NO4S
((4-Chloro-2-nitrophenyl)sulfonyl)-4-oxachroman-6-ylamine chemical structure, C14H11ClN2O6S, CAS 1024448-57-4
((4-Chloro-2-nitrophenyl)sulfonyl)-4-oxachroman-6-ylamine
CAS 1024448-57-4C14H11ClN2O6S
5-(2,3-Dihydro-1,4-benzodioxin-6-ylsulfamoyl)-N,2-dimethylbenzamide chemical structure, C17H18N2O5S, CAS 892694-13-2
5-(2,3-Dihydro-1,4-benzodioxin-6-ylsulfamoyl)-N,2-dimethylbenzamide
CAS 892694-13-2C17H18N2O5S
2-Amino-N-(2,3-dihydro-1,4-benzodioxin-6-yl)benzene-1-sulfonamide chemical structure, C14H14N2O4S, CAS 1040334-54-0
2-Amino-N-(2,3-dihydro-1,4-benzodioxin-6-yl)benzene-1-sulfonamide
CAS 1040334-54-0C14H14N2O4S
N-(7-Amino-2,3-dihydro-1,4-benzodioxin-6-yl)-4-nitrobenzene-1-sulfonamide chemical structure, C14H13N3O6S, CAS 2138525-46-7
N-(7-Amino-2,3-dihydro-1,4-benzodioxin-6-yl)-4-nitrobenzene-1-sulfonamide
CAS 2138525-46-7C14H13N3O6S
N-(7-Amino-2,3-dihydro-1,4-benzodioxin-6-yl)-2-nitrobenzene-1-sulfonamide chemical structure, C14H13N3O6S, CAS 2138555-93-6
N-(7-Amino-2,3-dihydro-1,4-benzodioxin-6-yl)-2-nitrobenzene-1-sulfonamide
CAS 2138555-93-6C14H13N3O6S