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Murcko scaffold

Ring system with 3 rings and 19 atoms

20 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
20
With full pages
4
Scaffold SMILES

c1ccc(SCc2c[nH]nc2-c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(SCc2c[nH]nc2-c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

5-Chloro-4-{[(2,3-dichlorophenyl)sulfanyl]methyl}-1-methyl-3-phenyl-1H-pyrazole chemical structure, C17H13Cl3N2S, CAS 318248-36-1
5-Chloro-4-{[(2,3-dichlorophenyl)sulfanyl]methyl}-1-methyl-3-phenyl-1H-pyrazole
CAS 318248-36-1C17H13Cl3N2S
(5-Chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl 4-fluorophenyl sulfide chemical structure, C17H14ClFN2S, CAS 318234-11-6
(5-Chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl 4-fluorophenyl sulfide
CAS 318234-11-6C17H14ClFN2S
(5-Chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl phenyl sulfide chemical structure, C17H15ClN2S, CAS 318234-09-2
(5-Chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl phenyl sulfide
CAS 318234-09-2C17H15ClN2S
5-Chloro-4-{[(2,4-dimethylphenyl)sulfanyl]methyl}-1-methyl-3-phenyl-1H-pyrazole chemical structure, C19H19ClN2S, CAS 318234-14-9
5-Chloro-4-{[(2,4-dimethylphenyl)sulfanyl]methyl}-1-methyl-3-phenyl-1H-pyrazole
CAS 318234-14-9C19H19ClN2S
2-[(5-Chloro-1-methyl-3-phenylpyrazol-4-yl)methylsulfanyl]benzoic acid chemical structure, C18H15ClN2O2S, CAS 318234-17-2
2-[(5-Chloro-1-methyl-3-phenylpyrazol-4-yl)methylsulfanyl]benzoic acid
CAS 318234-17-2C18H15ClN2O2S
(5-Chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl 4-chlorophenyl sulfide chemical structure, C17H14Cl2N2S, CAS 321538-21-0
(5-Chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl 4-chlorophenyl sulfide
CAS 321538-21-0C17H14Cl2N2S
5-Chloro-1-methyl-4-{[(4-methylphenyl)sulfanyl]methyl}-3-phenyl-1H-pyrazole chemical structure, C18H17ClN2S, CAS 318234-04-7
5-Chloro-1-methyl-4-{[(4-methylphenyl)sulfanyl]methyl}-3-phenyl-1H-pyrazole
CAS 318234-04-7C18H17ClN2S
(5-Chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl 2,3,4,5,6-pentafluorophenyl sulfide chemical structure, C17H10ClF5N2S, CAS 956949-82-9
(5-Chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl 2,3,4,5,6-pentafluorophenyl sulfide
CAS 956949-82-9C17H10ClF5N2S
5-Chloro-1-methyl-4-{[(3-methylphenyl)sulfanyl]methyl}-3-phenyl-1H-pyrazole chemical structure, C18H17ClN2S, CAS 318234-15-0
5-Chloro-1-methyl-4-{[(3-methylphenyl)sulfanyl]methyl}-3-phenyl-1H-pyrazole
CAS 318234-15-0C18H17ClN2S
5-Chloro-4-{[(2,5-dimethylphenyl)sulfanyl]methyl}-1-methyl-3-phenyl-1H-pyrazole chemical structure, C19H19ClN2S, CAS 318234-13-8
5-Chloro-4-{[(2,5-dimethylphenyl)sulfanyl]methyl}-1-methyl-3-phenyl-1H-pyrazole
CAS 318234-13-8C19H19ClN2S
5-Chloro-4-{[(2,5-dichlorophenyl)sulfanyl]methyl}-1-methyl-3-phenyl-1H-pyrazole chemical structure, C17H13Cl3N2S, CAS 956795-51-0
5-Chloro-4-{[(2,5-dichlorophenyl)sulfanyl]methyl}-1-methyl-3-phenyl-1H-pyrazole
CAS 956795-51-0C17H13Cl3N2S
(5-Chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl 2-chlorophenyl sulfide chemical structure, C17H14Cl2N2S, CAS 318234-07-0
(5-Chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl 2-chlorophenyl sulfide
CAS 318234-07-0C17H14Cl2N2S
5-Chloro-4-{[(2-ethylphenyl)sulfanyl]methyl}-1-methyl-3-phenyl-1H-pyrazole chemical structure, C19H19ClN2S, CAS 318234-18-3
5-Chloro-4-{[(2-ethylphenyl)sulfanyl]methyl}-1-methyl-3-phenyl-1H-pyrazole
CAS 318234-18-3C19H19ClN2S
(5-Chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl 3-chlorophenyl sulfide chemical structure, C17H14Cl2N2S, CAS 318234-08-1
(5-Chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl 3-chlorophenyl sulfide
CAS 318234-08-1C17H14Cl2N2S
5-Chloro-4-{[(2,4-dichlorophenyl)sulfanyl]methyl}-1-methyl-3-phenyl-1H-pyrazole chemical structure, C17H13Cl3N2S, CAS 956502-14-0
5-Chloro-4-{[(2,4-dichlorophenyl)sulfanyl]methyl}-1-methyl-3-phenyl-1H-pyrazole
CAS 956502-14-0C17H13Cl3N2S
4-{[(4-Bromophenyl)sulfanyl]methyl}-5-chloro-1-methyl-3-phenyl-1H-pyrazole chemical structure, C17H14BrClN2S, CAS 318234-10-5
4-{[(4-Bromophenyl)sulfanyl]methyl}-5-chloro-1-methyl-3-phenyl-1H-pyrazole
CAS 318234-10-5C17H14BrClN2S
5-Chloro-1-methyl-3-phenyl-4-[(4-propan-2-ylphenyl)sulfanylmethyl]pyrazole chemical structure, C20H21ClN2S, CAS 318234-19-4
5-Chloro-1-methyl-3-phenyl-4-[(4-propan-2-ylphenyl)sulfanylmethyl]pyrazole
CAS 318234-19-4C20H21ClN2S
Methyl 2-{[(5-chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl]sulfanyl}benzenecarboxylate chemical structure, C19H17ClN2O2S, CAS 318234-12-7
Methyl 2-{[(5-chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl]sulfanyl}benzenecarboxylate
CAS 318234-12-7C19H17ClN2O2S
5-Chloro-4-{[(2,6-dichlorophenyl)sulfanyl]methyl}-1-methyl-3-phenyl-1H-pyrazole chemical structure, C17H13Cl3N2S, CAS 318234-03-6
5-Chloro-4-{[(2,6-dichlorophenyl)sulfanyl]methyl}-1-methyl-3-phenyl-1H-pyrazole
CAS 318234-03-6C17H13Cl3N2S
(5-Chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl 3-(trifluoromethyl)phenyl sulfide chemical structure, C18H14ClF3N2S, CAS 318234-16-1
(5-Chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl 3-(trifluoromethyl)phenyl sulfide
CAS 318234-16-1C18H14ClF3N2S