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Murcko scaffold

Ring system with 3 rings and 18 atoms

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
7
With full pages
4
Scaffold SMILES

c1ccc(-c2csc(Nc3ncccn3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2csc(Nc3ncccn3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

[4-(4-Methoxy-3-methyl-phenyl)-thiazol-2-yl]-pyrimidin-2-yl-amine chemical structure, C15H14N4OS, CAS 667887-60-7
[4-(4-Methoxy-3-methyl-phenyl)-thiazol-2-yl]-pyrimidin-2-yl-amine
CAS 667887-60-7C15H14N4OS
N-[4-(4-Ethylphenyl)-1,3-thiazol-2-yl]pyrimidin-2-amine chemical structure, C15H14N4S, CAS 690689-33-9
N-[4-(4-Ethylphenyl)-1,3-thiazol-2-yl]pyrimidin-2-amine
CAS 690689-33-9C15H14N4S
N-[4-(2,5-Dimethylphenyl)-1,3-thiazol-2-yl]pyrimidin-2-amine chemical structure, C15H14N4S, CAS 690696-96-9
N-[4-(2,5-Dimethylphenyl)-1,3-thiazol-2-yl]pyrimidin-2-amine
CAS 690696-96-9C15H14N4S
4-(4-Fluoro-3-methylphenyl)-N-pyrimidin-2-yl-1,3-thiazol-2-amine chemical structure, C14H11FN4S, CAS 690696-21-0
4-(4-Fluoro-3-methylphenyl)-N-pyrimidin-2-yl-1,3-thiazol-2-amine
CAS 690696-21-0C14H11FN4S
4-[2-(Pyrimidin-2-ylamino)-1,3-thiazol-4-yl]phenol chemical structure, C13H10N4OS, CAS 708289-74-1
4-[2-(Pyrimidin-2-ylamino)-1,3-thiazol-4-yl]phenol
CAS 708289-74-1C13H10N4OS
2-Pyrimidinamine, 4,6-dimethyl-N-[4-(4-methylphenyl)-2-thiazolyl]- chemical structure, C16H16N4S, CAS 88067-19-0
2-Pyrimidinamine, 4,6-dimethyl-N-[4-(4-methylphenyl)-2-thiazolyl]-
CAS 88067-19-0C16H16N4S
RefChem:382102 chemical structure, C15H14N4S, CAS 88067-18-9
RefChem:382102
CAS 88067-18-9C15H14N4S