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Murcko scaffold

N,4-diphenyl-1,3-thiazol-2-amine scaffold

471 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
471
With full pages
49
Scaffold SMILES

c1ccc(Nc2nc(-c3ccccc3)cs2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N,4-diphenyl-1,3-thiazol-2-amine page
Murcko scaffold c1ccc(Nc2nc(-c3ccccc3)cs2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 471 chemicals

5-Thiazoleacetic acid, 4-(4-chlorophenyl)-2-(phenylamino)- chemical structure, C17H13ClN2O2S, CAS 49779-95-5
5-Thiazoleacetic acid, 4-(4-chlorophenyl)-2-(phenylamino)-
CAS 49779-95-5C17H13ClN2O2S
N-(3-(3-(Dimethylamino)propyl)-4-(4-methoxyphenyl)-1,3-thiazol-2(3H)-ylidene)aniline chemical structure, C21H25N3OS, CAS 301675-80-9
N-(3-(3-(Dimethylamino)propyl)-4-(4-methoxyphenyl)-1,3-thiazol-2(3H)-ylidene)aniline
CAS 301675-80-9C21H25N3OS
N-(3-Allyl-4-(4-chlorophenyl)-1,3-thiazol-2(3H)-ylidene)-2-methoxyaniline hydrobromide chemical structure, C19H17ClN2OS, CAS 1049970-43-5
N-(3-Allyl-4-(4-chlorophenyl)-1,3-thiazol-2(3H)-ylidene)-2-methoxyaniline hydrobromide
CAS 1049970-43-5C19H17ClN2OS
N-{4-(4-Bromophenyl)-3-[3-(dimethylamino) propyl]thiazol-2(3H)-ylidene}aniline chemical structure, C20H22BrN3S, CAS 304443-97-8
N-{4-(4-Bromophenyl)-3-[3-(dimethylamino) propyl]thiazol-2(3H)-ylidene}aniline
CAS 304443-97-8C20H22BrN3S
N-(4-Methylphenyl)-4-phenyl-1,3-thiazol-2-amine chemical structure, C16H14N2S, CAS 16098-04-7
N-(4-Methylphenyl)-4-phenyl-1,3-thiazol-2-amine
CAS 16098-04-7C16H14N2S
2-Thiazolamine, 4-(4-methylphenyl)-N-phenyl- chemical structure, C16H14N2S, CAS 93020-56-5
2-Thiazolamine, 4-(4-methylphenyl)-N-phenyl-
CAS 93020-56-5C16H14N2S
N-(2-Chlorophenyl)-4-(4-fluorophenyl)-1,3-thiazol-2-amine chemical structure, C15H10ClFN2S, CAS 61383-54-8
N-(2-Chlorophenyl)-4-(4-fluorophenyl)-1,3-thiazol-2-amine
CAS 61383-54-8C15H10ClFN2S
N-(4-Fluorophenyl)-4-phenyl-1,3-thiazol-2-amine chemical structure, C15H11FN2S, CAS 339303-87-6
N-(4-Fluorophenyl)-4-phenyl-1,3-thiazol-2-amine
CAS 339303-87-6C15H11FN2S
4-(4-Fluorophenyl)-N-(4-methylphenyl)-2-thiazolamine chemical structure, C16H13FN2S, CAS 405921-11-1
4-(4-Fluorophenyl)-N-(4-methylphenyl)-2-thiazolamine
CAS 405921-11-1C16H13FN2S
4-(4-Bromophenyl)-N-(4-fluorophenyl)-1,3-thiazol-2-amine chemical structure, C15H10BrFN2S, CAS 340695-51-4
4-(4-Bromophenyl)-N-(4-fluorophenyl)-1,3-thiazol-2-amine
CAS 340695-51-4C15H10BrFN2S
N,4-bis(4-fluorophenyl)-1,3-thiazol-2-amine chemical structure, C15H10F2N2S, CAS 1554-59-2
N,4-bis(4-fluorophenyl)-1,3-thiazol-2-amine
CAS 1554-59-2C15H10F2N2S
4-(4-Chlorophenyl)-N-(3-methylphenyl)-1,3-thiazol-2-amine chemical structure, C16H13ClN2S, CAS 21344-82-1
4-(4-Chlorophenyl)-N-(3-methylphenyl)-1,3-thiazol-2-amine
CAS 21344-82-1C16H13ClN2S
4-(4-Bromophenyl)-N-phenyl-1,3-thiazol-2-amine chemical structure, C15H11BrN2S, CAS 42056-77-9
4-(4-Bromophenyl)-N-phenyl-1,3-thiazol-2-amine
CAS 42056-77-9C15H11BrN2S
2-(4-(4-Chlorophenyl)-2-(phenylimino)-1,3-thiazol-3(2H)-yl)ethanol chemical structure, C17H15ClN2OS, CAS 328282-84-4
2-(4-(4-Chlorophenyl)-2-(phenylimino)-1,3-thiazol-3(2H)-yl)ethanol
CAS 328282-84-4C17H15ClN2OS
3(2H)-Thiazoleethanol, 4-(4-fluorophenyl)-2-(phenylimino)-, (2Z)- chemical structure, C17H15FN2OS, CAS 1049981-02-3
3(2H)-Thiazoleethanol, 4-(4-fluorophenyl)-2-(phenylimino)-, (2Z)-
CAS 1049981-02-3C17H15FN2OS
4-(4-Chlorophenyl)-N-(4-ethoxyphenyl)thiazol-2-amine chemical structure, C17H15ClN2OS, CAS 328127-95-3
4-(4-Chlorophenyl)-N-(4-ethoxyphenyl)thiazol-2-amine
CAS 328127-95-3C17H15ClN2OS
N-(2-Methylphenyl)-4-(4-nitrophenyl)-1,3-thiazol-2-amine chemical structure, C16H13N3O2S, CAS 313230-01-2
N-(2-Methylphenyl)-4-(4-nitrophenyl)-1,3-thiazol-2-amine
CAS 313230-01-2C16H13N3O2S
4-(3,4-Dichlorophenyl)-N-phenyl-1,3-thiazol-2-amine chemical structure, C15H10Cl2N2S, CAS 67241-16-1
4-(3,4-Dichlorophenyl)-N-phenyl-1,3-thiazol-2-amine
CAS 67241-16-1C15H10Cl2N2S
4-(4-Chlorophenyl)-N-(2-methoxyphenyl)-1,3-thiazol-2-amine chemical structure, C16H13ClN2OS, CAS 21344-84-3
4-(4-Chlorophenyl)-N-(2-methoxyphenyl)-1,3-thiazol-2-amine
CAS 21344-84-3C16H13ClN2OS
4-(4-Fluorophenyl)-N-(2-methoxyphenyl)-1,3-thiazol-2-amine chemical structure, C16H13FN2OS, CAS 61383-58-2
4-(4-Fluorophenyl)-N-(2-methoxyphenyl)-1,3-thiazol-2-amine
CAS 61383-58-2C16H13FN2OS
N-(2-Methoxyphenyl)-4-(4-nitrophenyl)-1,3-thiazol-2-amine chemical structure, C16H13N3O3S, CAS 312915-05-2
N-(2-Methoxyphenyl)-4-(4-nitrophenyl)-1,3-thiazol-2-amine
CAS 312915-05-2C16H13N3O3S
N-(3-Chloro-4-methylphenyl)-4-(2,5-dimethylphenyl)-1,3-thiazol-2-amine chemical structure, C18H17ClN2S, CAS 339293-11-7
N-(3-Chloro-4-methylphenyl)-4-(2,5-dimethylphenyl)-1,3-thiazol-2-amine
CAS 339293-11-7C18H17ClN2S
N-(4-Methylphenyl)-4-(4-nitrophenyl)-1,3-thiazol-2-amine chemical structure, C16H13N3O2S, CAS 312915-04-1
N-(4-Methylphenyl)-4-(4-nitrophenyl)-1,3-thiazol-2-amine
CAS 312915-04-1C16H13N3O2S
N-(4-Fluorophenyl)-4-[4-(2-methylpropyl)phenyl]-1,3-thiazol-2-amine chemical structure, C19H19FN2S, CAS 339994-85-3
N-(4-Fluorophenyl)-4-[4-(2-methylpropyl)phenyl]-1,3-thiazol-2-amine
CAS 339994-85-3C19H19FN2S