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Murcko scaffold

Ring system with 3 rings and 18 atoms

179 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
179
With full pages
36
Scaffold SMILES

c1ccc(Cn2ccc(-c3ccccc3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Cn2ccc(-c3ccccc3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 179 chemicals

Pyrazol-5-amine, 1-benzyl-3-(3-bromophenyl)- chemical structure, C16H14BrN3, CAS 424806-56-4
Pyrazol-5-amine, 1-benzyl-3-(3-bromophenyl)-
CAS 424806-56-4C16H14BrN3
1-(2,4-Dichlorobenzyl)-3-phenyl-1H-pyrazole-4-carbaldehyde chemical structure, C17H12Cl2N2O, CAS 312275-55-1
1-(2,4-Dichlorobenzyl)-3-phenyl-1H-pyrazole-4-carbaldehyde
CAS 312275-55-1C17H12Cl2N2O
1-(4-Bromobenzyl)-3-phenyl-1H-pyrazole-4-carbaldehyde chemical structure, C17H13BrN2O, CAS 514801-11-7
1-(4-Bromobenzyl)-3-phenyl-1H-pyrazole-4-carbaldehyde
CAS 514801-11-7C17H13BrN2O
1-(2-Chloro-6-fluorobenzyl)-3-phenyl-1H-pyrazole-4-carbaldehyde chemical structure, C17H12ClFN2O, CAS 492426-26-3
1-(2-Chloro-6-fluorobenzyl)-3-phenyl-1H-pyrazole-4-carbaldehyde
CAS 492426-26-3C17H12ClFN2O
1-Benzyl-3-phenyl-1H-pyrazol-5-amine chemical structure, C16H15N3, CAS 3528-41-4
1-Benzyl-3-phenyl-1H-pyrazol-5-amine
CAS 3528-41-4C16H15N3
N-[2-[(3-Chlorophenyl)methyl]-5-phenylpyrazol-3-yl]acetamide chemical structure, C18H16ClN3O, CAS 311777-94-3
N-[2-[(3-Chlorophenyl)methyl]-5-phenylpyrazol-3-yl]acetamide
CAS 311777-94-3C18H16ClN3O
2-(4-Chloro-benzyl)-5-phenyl-2H-pyrazol-3-ylamine chemical structure, C16H14ClN3, CAS 245556-52-9
2-(4-Chloro-benzyl)-5-phenyl-2H-pyrazol-3-ylamine
CAS 245556-52-9C16H14ClN3
N-[3-(4-Bromophenyl)-1-(4-chlorobenzyl)-1H-pyrazol-5-yl]acetamide chemical structure, C18H15BrClN3O, CAS 400744-19-6
N-[3-(4-Bromophenyl)-1-(4-chlorobenzyl)-1H-pyrazol-5-yl]acetamide
CAS 400744-19-6C18H15BrClN3O
N-[5-(4-Chlorophenyl)-2-[(4-chlorophenyl)methyl]pyrazol-3-yl]acetamide chemical structure, C18H15Cl2N3O, CAS 6078-10-0
N-[5-(4-Chlorophenyl)-2-[(4-chlorophenyl)methyl]pyrazol-3-yl]acetamide
CAS 6078-10-0C18H15Cl2N3O
1-Benzyl-3-(3,4-dimethoxyphenyl)-1H-pyrazole-4-carbaldehyde chemical structure, C19H18N2O3, CAS 588674-24-2
1-Benzyl-3-(3,4-dimethoxyphenyl)-1H-pyrazole-4-carbaldehyde
CAS 588674-24-2C19H18N2O3
1-Benzyl-3-(4-methylphenyl)-1H-pyrazole-4-carbaldehyde chemical structure, C18H16N2O, CAS 956783-07-6
1-Benzyl-3-(4-methylphenyl)-1H-pyrazole-4-carbaldehyde
CAS 956783-07-6C18H16N2O
3-(4-Methylphenyl)-1-[(4-methylphenyl)methyl]-1H-pyrazole-4-carbaldehyde chemical structure, C19H18N2O, CAS 956785-40-3
3-(4-Methylphenyl)-1-[(4-methylphenyl)methyl]-1H-pyrazole-4-carbaldehyde
CAS 956785-40-3C19H18N2O
1-Benzyl-3-(4-ethylphenyl)-1H-pyrazole-4-carbaldehyde chemical structure, C19H18N2O, CAS 956513-35-2
1-Benzyl-3-(4-ethylphenyl)-1H-pyrazole-4-carbaldehyde
CAS 956513-35-2C19H18N2O
1-Benzyl-3-(4-ethylphenyl)-1H-pyrazole-4-carboxylic acid chemical structure, C19H18N2O2, CAS 956386-81-5
1-Benzyl-3-(4-ethylphenyl)-1H-pyrazole-4-carboxylic acid
CAS 956386-81-5C19H18N2O2
1-Benzyl-3-(2-methoxyphenyl)-1H-pyrazole-4-carbaldehyde chemical structure, C18H16N2O2, CAS 956261-61-3
1-Benzyl-3-(2-methoxyphenyl)-1H-pyrazole-4-carbaldehyde
CAS 956261-61-3C18H16N2O2
(2E)-3-[1-Benzyl-3-(4-methylphenyl)-1H-pyrazol-4-yl]acrylic acid chemical structure, C20H18N2O2, CAS 956453-11-5
(2E)-3-[1-Benzyl-3-(4-methylphenyl)-1H-pyrazol-4-yl]acrylic acid
CAS 956453-11-5C20H18N2O2
1-Benzyl-3-(4-methylphenyl)-1H-pyrazole-4-carboxylic acid chemical structure, C18H16N2O2, CAS 956453-12-6
1-Benzyl-3-(4-methylphenyl)-1H-pyrazole-4-carboxylic acid
CAS 956453-12-6C18H16N2O2
1-Benzyl-3-(3,4-dimethylphenyl)-1H-pyrazole-4-carboxylic acid chemical structure, C19H18N2O2, CAS 956199-09-0
1-Benzyl-3-(3,4-dimethylphenyl)-1H-pyrazole-4-carboxylic acid
CAS 956199-09-0C19H18N2O2
1-[(2-Chlorophenyl)methyl]-3-phenyl-1H-pyrazole-4-carboxylic acid chemical structure, C17H13ClN2O2, CAS 956199-29-4
1-[(2-Chlorophenyl)methyl]-3-phenyl-1H-pyrazole-4-carboxylic acid
CAS 956199-29-4C17H13ClN2O2
3-{1-[(2-Chlorophenyl)methyl]-3-phenyl-1H-pyrazol-4-yl}prop-2-enoic acid chemical structure, C19H15ClN2O2, CAS 956355-25-2
3-{1-[(2-Chlorophenyl)methyl]-3-phenyl-1H-pyrazol-4-yl}prop-2-enoic acid
CAS 956355-25-2C19H15ClN2O2
1-Benzyl-3-(4-chlorophenyl)-1H-pyrazole-4-carbaldehyde chemical structure, C17H13ClN2O, CAS 956373-98-1
1-Benzyl-3-(4-chlorophenyl)-1H-pyrazole-4-carbaldehyde
CAS 956373-98-1C17H13ClN2O
({1-[(2-Chlorophenyl)methyl]-3-phenyl-1H-pyrazol-4-yl}methyl)(methyl)amine chemical structure, C18H18ClN3, CAS 956262-06-9
({1-[(2-Chlorophenyl)methyl]-3-phenyl-1H-pyrazol-4-yl}methyl)(methyl)amine
CAS 956262-06-9C18H18ClN3
1-Benzyl-3-(4-chlorophenyl)-1H-pyrazole-4-carboxylic acid chemical structure, C17H13ClN2O2, CAS 956261-56-6
1-Benzyl-3-(4-chlorophenyl)-1H-pyrazole-4-carboxylic acid
CAS 956261-56-6C17H13ClN2O2
1-Benzyl-3-(3-methoxyphenyl)-1H-pyrazole-4-carbaldehyde chemical structure, C18H16N2O2, CAS 956360-54-6
1-Benzyl-3-(3-methoxyphenyl)-1H-pyrazole-4-carbaldehyde
CAS 956360-54-6C18H16N2O2