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Murcko scaffold

5-((E)-3-Phenylallylidene)-2-thioxothiazolidin-4-one scaffold

62 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 16
Chemicals: 62
With full pages: 9

Scaffold SMILES

O=C1NC(=S)SC1=CC=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 5-((E)-3-Phenylallylidene)-2-thioxothiazolidin-4-one page

Murcko scaffold O=C1NC(=S)SC1=CC=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 62 chemicals

3-[(5Z)-5-[(2Z)-2-Methyl-3-phenylprop-2-en-1-ylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoic acid chemical structure, C16H15NO3S2

3-[(5Z)-5-[(2Z)-2-Methyl-3-phenylprop-2-en-1-ylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoic acid

C₁₆H₁₅NO₃S₂

2-[(5E)-4-Oxo-5-[(2E)-3-phenylprop-2-en-1-ylidene]-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid chemical structure, C14H11NO3S2, CAS 82158-77-8

2-[(5E)-4-Oxo-5-[(2E)-3-phenylprop-2-en-1-ylidene]-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid

CAS 82158-77-8C₁₄H₁₁NO₃S₂

2-((Z)-4-Oxo-5-((E)-3-phenylallylidene)-2-thioxothiazolidin-3-yl)acetic acid chemical structure, C14H11NO3S2, CAS 1800597-47-0

2-((Z)-4-Oxo-5-((E)-3-phenylallylidene)-2-thioxothiazolidin-3-yl)acetic acid

CAS 1800597-47-0C₁₄H₁₁NO₃S₂

2-((E)-5-((Z)-2-Methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid chemical structure, C15H13NO3S2, CAS 124782-64-5

2-((E)-5-((Z)-2-Methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid

CAS 124782-64-5C₁₅H₁₃NO₃S₂

2-[(5Z)-5-[(2Z)-2-Methyl-3-phenylprop-2-en-1-ylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid chemical structure, C15H13NO3S2, CAS 124782-63-4

2-[(5Z)-5-[(2Z)-2-Methyl-3-phenylprop-2-en-1-ylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid

CAS 124782-63-4C₁₅H₁₃NO₃S₂

5-[3-(4-Dimethylamino-phenyl)-allylidene]-2-thioxo-thiazolidin-4-one chemical structure, C14H14N2OS2, CAS 1055980-82-9

5-[3-(4-Dimethylamino-phenyl)-allylidene]-2-thioxo-thiazolidin-4-one

CAS 1055980-82-9C₁₄H₁₄N₂OS₂

5-((E)-3-Phenylallylidene)-2-thioxothiazolidin-4-one chemical structure, C12H9NOS2, CAS 1231182-07-2

5-((E)-3-Phenylallylidene)-2-thioxothiazolidin-4-one

CAS 1231182-07-2C₁₂H₉NOS₂

5-Cinnamylidenerhodanine chemical structure, C12H9NOS2, CAS 15328-87-7

5-Cinnamylidenerhodanine

CAS 15328-87-7C₁₂H₉NOS₂

5-((2E)-3-Phenylprop-2-enylidene)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C12H9NOS2, CAS 310463-02-6

5-((2E)-3-Phenylprop-2-enylidene)-2-thioxo-1,3-thiazolidin-4-one

CAS 310463-02-6C₁₂H₉NOS₂

5-[3-(2-Chlorophenyl)-2-propen-1-ylidene]-2-thioxo-4-thiazolidinone chemical structure, C12H8ClNOS2, CAS 15328-88-8

5-[3-(2-Chlorophenyl)-2-propen-1-ylidene]-2-thioxo-4-thiazolidinone

CAS 15328-88-8C₁₂H₈ClNOS₂

4-Thiazolidinone, 5-[3-(4-methoxyphenyl)-2-propenylidene]-2-thioxo- chemical structure, C13H11NO2S2, CAS 15328-92-4

4-Thiazolidinone, 5-[3-(4-methoxyphenyl)-2-propenylidene]-2-thioxo-

CAS 15328-92-4C₁₃H₁₁NO₂S₂

4-(4-Oxo-5-(3-phenylprop-2-en-1-ylidene)-2-sulfanylidene-1,3-thiazolidin-3-yl)butanoic acid chemical structure, C16H15NO3S2, CAS 17385-92-1

4-(4-Oxo-5-(3-phenylprop-2-en-1-ylidene)-2-sulfanylidene-1,3-thiazolidin-3-yl)butanoic acid

CAS 17385-92-1C₁₆H₁₅NO₃S₂

(5E)-5-{(2E)-3-[4-(Dimethylamino)phenyl]prop-2-en-1-ylidene}-3-(prop-2-en-1-yl)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C17H18N2OS2, CAS 312607-92-4

(5E)-5-{(2E)-3-[4-(Dimethylamino)phenyl]prop-2-en-1-ylidene}-3-(prop-2-en-1-yl)-2-thioxo-1,3-thiazolidin-4-one

CAS 312607-92-4C₁₇H₁₈N₂OS₂

Epalrestat chemical structure, C15H13NO3S2, CAS 82159-09-9

CAS 82159-09-9C₁₅H₁₃NO₃S₂

(5E)-5-[(E)-3-(2-Nitrophenyl)prop-2-enylidene]-2-sulfanylidene-1,3-thiazolidin-4-one chemical structure, C12H8N2O3S2, CAS 6329-19-7

(5E)-5-[(E)-3-(2-Nitrophenyl)prop-2-enylidene]-2-sulfanylidene-1,3-thiazolidin-4-one

CAS 6329-19-7C₁₂H₈N₂O₃S₂

6-(4-Oxo-5-(3-phenylallylidene)-2-thioxothiazolidin-3-yl)hexanoic acid chemical structure, C18H19NO3S2, CAS 15059-29-7

6-(4-Oxo-5-(3-phenylallylidene)-2-thioxothiazolidin-3-yl)hexanoic acid

CAS 15059-29-7C₁₈H₁₉NO₃S₂

Methyl {(5E)-4-oxo-5-[(2E)-3-phenylprop-2-enylidene]-2-thioxo-1,3-thiazolidin-3-yl}acetate chemical structure, C15H13NO3S2, CAS 307538-60-9

Methyl {(5E)-4-oxo-5-[(2E)-3-phenylprop-2-enylidene]-2-thioxo-1,3-thiazolidin-3-yl}acetate

CAS 307538-60-9C₁₅H₁₃NO₃S₂

Ethyl 3-[5-((2E)-3-phenylprop-2-enylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]propanoate chemical structure, C17H17NO3S2, CAS 465508-66-1

Ethyl 3-[5-((2E)-3-phenylprop-2-enylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]propanoate

CAS 465508-66-1C₁₇H₁₇NO₃S₂

Methyl 3-{(5E)-4-oxo-5-[(2E)-3-phenylprop-2-en-1-ylidene]-2-thioxo-1,3-thiazolidin-3-yl}propanoate chemical structure, C16H15NO3S2, CAS 303117-21-7

Methyl 3-{(5E)-4-oxo-5-[(2E)-3-phenylprop-2-en-1-ylidene]-2-thioxo-1,3-thiazolidin-3-yl}propanoate

CAS 303117-21-7C₁₆H₁₅NO₃S₂

3-[4-Oxo-5-(3-phenyl-allylidene)-2-thioxo-thiazolidin-3-yl]-propionic acid chemical structure, C15H13NO3S2

3-[4-Oxo-5-(3-phenyl-allylidene)-2-thioxo-thiazolidin-3-yl]-propionic acid

C₁₅H₁₃NO₃S₂

3-[4-Oxo-5-(3-phenylprop-2-en-1-ylidene)-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoic acid chemical structure, C15H13NO3S2, CAS 7025-17-4

3-[4-Oxo-5-(3-phenylprop-2-en-1-ylidene)-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoic acid

CAS 7025-17-4C₁₅H₁₃NO₃S₂

2-((E)-5-((E)-2-Methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid chemical structure, C15H13NO3S2, CAS 863988-85-6

2-((E)-5-((E)-2-Methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid

CAS 863988-85-6C₁₅H₁₃NO₃S₂

3-((E)-5-((E)-2-Methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl)propanoic acid chemical structure, C16H15NO3S2, CAS 306323-56-8

3-((E)-5-((E)-2-Methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl)propanoic acid

CAS 306323-56-8C₁₆H₁₅NO₃S₂

3-[5-(2-Methyl-3-phenylprop-2-enylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]propanoic acid chemical structure, C16H15NO3S2, CAS 1800597-49-2

3-[5-(2-Methyl-3-phenylprop-2-enylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]propanoic acid

CAS 1800597-49-2C₁₆H₁₅NO₃S₂