Murcko scaffold
Ring system with 3 rings and 18 atoms
116 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 18
- Chemicals
- 116
- With full pages
- 18
Scaffold SMILES
O=C(Nc1ccccc1)c1cc2cccnc2s1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 116 chemicals
![N-(4-Acetylphenyl)-3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide chemical structure, C18H17N3O2S, CAS 402954-19-2](/s/BUZQLKXFKWGWSZ-UHFFFAOYSA-N.svg)
N-(4-Acetylphenyl)-3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
CAS 402954-19-2C18H17N3O2S
![3-Amino-N-(3-chlorophenyl)-4-(methoxymethyl)-6-methylthieno[2,3-b]pyridine-2-carboxamide chemical structure, C17H16ClN3O2S, CAS 381186-87-4](/s/VOUBWPPYTBALCS-UHFFFAOYSA-N.svg)
3-Amino-N-(3-chlorophenyl)-4-(methoxymethyl)-6-methylthieno[2,3-b]pyridine-2-carboxamide
CAS 381186-87-4C17H16ClN3O2S
![3-Amino-4-(methoxymethyl)-6-methyl-N-phenylthieno[2,3-b]pyridine-2-carboxamide chemical structure, C17H17N3O2S, CAS 185430-54-0](/s/NVMLWIVBRXDHGT-UHFFFAOYSA-N.svg)
3-Amino-4-(methoxymethyl)-6-methyl-N-phenylthieno[2,3-b]pyridine-2-carboxamide
CAS 185430-54-0C17H17N3O2S
![3-Amino-N-(4-methoxyphenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide chemical structure, C17H17N3O2S, CAS 299464-83-8](/s/UGCUSLLCJRNUPD-UHFFFAOYSA-N.svg)
3-Amino-N-(4-methoxyphenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
CAS 299464-83-8C17H17N3O2S
3-Amino-4,6-dimethyl-N-phenylthieno(2,3-b)pyridine-2-carboxamide
CAS 72701-64-5C16H15N3OS
![3-Amino-N-(3-chloro-4-fluorophenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide chemical structure, C16H13ClFN3OS, CAS 371118-27-3](/s/DZVFMKYWLTVCQC-UHFFFAOYSA-N.svg)
3-Amino-N-(3-chloro-4-fluorophenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
CAS 371118-27-3C16H13ClFN3OS
![3-Amino-N-(4-fluorophenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide chemical structure, C16H14FN3OS, CAS 340817-80-3](/s/HKRBXLITKWGPCH-UHFFFAOYSA-N.svg)
3-Amino-N-(4-fluorophenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
CAS 340817-80-3C16H14FN3OS
![3-Amino-N-(4-chlorophenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide chemical structure, C16H14ClN3OS, CAS 180792-99-8](/s/PGTFNOFNCGJFDD-UHFFFAOYSA-N.svg)
3-Amino-N-(4-chlorophenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
CAS 180792-99-8C16H14ClN3OS
![3-Amino-N-(2-fluorophenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide chemical structure, C16H14FN3OS, CAS 333329-26-3](/s/KKIYVNFPEVHFBC-UHFFFAOYSA-N.svg)
3-Amino-N-(2-fluorophenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
CAS 333329-26-3C16H14FN3OS
![N-(3-Acetylphenyl)-3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide chemical structure, C18H17N3O2S, CAS 691866-86-1](/s/IDYLMZDPRPFAKM-UHFFFAOYSA-N.svg)
N-(3-Acetylphenyl)-3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
CAS 691866-86-1C18H17N3O2S
![3-Amino-N-(3-chloro-4-methylphenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide chemical structure, C17H16ClN3OS, CAS 332949-95-8](/s/NOIVXXNMGMLVLD-UHFFFAOYSA-N.svg)
3-Amino-N-(3-chloro-4-methylphenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
CAS 332949-95-8C17H16ClN3OS
![3-Amino-N-(3-chloro-2-methylphenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide chemical structure, C17H16ClN3OS, CAS 332949-92-5](/s/ITUPHEVJIWNDSE-UHFFFAOYSA-N.svg)
3-Amino-N-(3-chloro-2-methylphenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
CAS 332949-92-5C17H16ClN3OS
![3-Amino-N-(5-chloro-2-methylphenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide chemical structure, C17H16ClN3OS, CAS 332949-93-6](/s/APSUVAOBLSJCEU-UHFFFAOYSA-N.svg)
3-Amino-N-(5-chloro-2-methylphenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
CAS 332949-93-6C17H16ClN3OS
![3-Amino-N-ethyl-4,6-dimethyl-N-phenylthieno[2,3-b]pyridine-2-carboxamide chemical structure, C18H19N3OS, CAS 691866-96-3](/s/NWVWFOLYVICZOV-UHFFFAOYSA-N.svg)
3-Amino-N-ethyl-4,6-dimethyl-N-phenylthieno[2,3-b]pyridine-2-carboxamide
CAS 691866-96-3C18H19N3OS
![3-Amino-N-(4-ethoxyphenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide chemical structure, C18H19N3O2S, CAS 444286-94-6](/s/YMEOUKHACVMFLV-UHFFFAOYSA-N.svg)
3-Amino-N-(4-ethoxyphenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
CAS 444286-94-6C18H19N3O2S
![3-Amino-N-(2-ethoxyphenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide chemical structure, C18H19N3O2S, CAS 685851-97-2](/s/NWPBIINCRFZSIN-UHFFFAOYSA-N.svg)
3-Amino-N-(2-ethoxyphenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
CAS 685851-97-2C18H19N3O2S
![3-Amino-N-(2-chlorophenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide chemical structure, C16H14ClN3OS, CAS 332950-02-4](/s/QPCXMDKFNQKVIC-UHFFFAOYSA-N.svg)
3-Amino-N-(2-chlorophenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
CAS 332950-02-4C16H14ClN3OS
![3-Amino-N-(3-methoxyphenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide chemical structure, C17H17N3O2S, CAS 691866-97-4](/s/AZKUWCFQFYNTPW-UHFFFAOYSA-N.svg)
3-Amino-N-(3-methoxyphenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
CAS 691866-97-4C17H17N3O2S
![3-Amino-N-(2,3-dimethylphenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide chemical structure, C18H19N3OS, CAS 313380-40-4](/s/LLXUBCHMTVDDFO-UHFFFAOYSA-N.svg)
3-Amino-N-(2,3-dimethylphenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
CAS 313380-40-4C18H19N3OS
![3-Amino-4-(methoxymethyl)-6-methyl-N-(3-methylphenyl)thieno[2,3-b]pyridine-2-carboxamide chemical structure, C18H19N3O2S, CAS 442672-80-2](/s/UDCLUSCNSYUGSS-UHFFFAOYSA-N.svg)
3-Amino-4-(methoxymethyl)-6-methyl-N-(3-methylphenyl)thieno[2,3-b]pyridine-2-carboxamide
CAS 442672-80-2C18H19N3O2S
![3-Amino-N-(4-ethylphenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide chemical structure, C18H19N3OS, CAS 332949-83-4](/s/YDYKEXGXDJRVML-UHFFFAOYSA-N.svg)
3-Amino-N-(4-ethylphenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
CAS 332949-83-4C18H19N3OS
![3-Amino-N-(2,4-dimethylphenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide chemical structure, C18H19N3OS, CAS 332949-84-5](/s/HNZVPIWVOPQWPL-UHFFFAOYSA-N.svg)
3-Amino-N-(2,4-dimethylphenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
CAS 332949-84-5C18H19N3OS
![3,6-Diamino-5-cyano-4-ethyl-N-phenylthieno[2,3-b]pyridine-2-carboxamide chemical structure, C17H15N5OS, CAS 184530-30-1](/s/YBLNRGSWEMWOJH-UHFFFAOYSA-N.svg)
3,6-Diamino-5-cyano-4-ethyl-N-phenylthieno[2,3-b]pyridine-2-carboxamide
CAS 184530-30-1C17H15N5OS
![3-Amino-N-(2-fluorophenyl)-4-(methoxymethyl)-6-methylthieno[2,3-b]pyridine-2-carboxamide chemical structure, C17H16FN3O2S, CAS 709000-68-0](/s/UGPJHGJGPIZKFA-UHFFFAOYSA-N.svg)
3-Amino-N-(2-fluorophenyl)-4-(methoxymethyl)-6-methylthieno[2,3-b]pyridine-2-carboxamide
CAS 709000-68-0C17H16FN3O2S
- 3-Amino-6-ethyl-N-(4-fluorophenyl)-5-methylthieno[2,3-b]pyridine-2-carboxamide369403-34-9C17H16FN3OS
- 3-Amino-N-(4-tert-butylphenyl)-6-methylthieno[2,3-b]pyridine-2-carboxamide445382-57-0C19H21N3OS
- 3-Amino-N-[2-chloro-5-(trifluoromethyl)phenyl]-6-(difluoromethyl)-4-methylthieno[2,3-b]pyridine-2-carboxamide515847-96-8C17H11ClF5N3OS
- 3,6-Diamino-N-(2-chloro-4-fluorophenyl)-5-cyanothieno[2,3-b]pyridine-2-carboxamide625369-90-6C15H9ClFN5OS
- 3-Amino-6-ethyl-5-methyl-N-[4-(trifluoromethoxy)phenyl]thieno[2,3-b]pyridine-2-carboxamide442669-36-5C18H16F3N3O2S
- 3-Amino-N-(4-chlorophenyl)-4-methyl-6-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide445382-77-4C16H11ClF3N3OS
- 3-Amino-N-(2-chlorophenyl)-6-ethyl-5-methyl-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide664999-38-6C18H15ClF3N3OS
- Ethyl 5-({[3-amino-4-(methoxymethyl)-6-methylthieno[2,3-b]pyridin-2-yl]carbonyl}amino)-2-chlorobenzoate663182-70-5C20H20ClN3O4S
- 3-Amino-N-(4-chlorophenyl)-4-(methoxymethyl)-6-methylthieno[2,3-b]pyridine-2-carboxamide353508-96-0C17H16ClN3O2S
- 3-Amino-4-(methoxymethyl)-N-(4-methoxyphenyl)-6-methylthieno[2,3-b]pyridine-2-carboxamide370848-32-1C18H19N3O3S
- 3-Amino-N-(2,5-dimethylphenyl)-4-methyl-6-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide445016-76-2C18H16F3N3OS
- 3-Amino-5-chloro-N-(2,4-dichlorophenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide663936-09-2C16H12Cl3N3OS
- 3-Amino-N-(4-bromophenyl)-4,5,6-trimethylthieno[2,3-b]pyridine-2-carboxamide313519-34-5C17H16BrN3OS
- 3-Amino-N-(2-chlorophenyl)-4-(methoxymethyl)-6-methylthieno[2,3-b]pyridine-2-carboxamide371139-01-4C17H16ClN3O2S
- 3-Amino-4-(methoxymethyl)-N-(2-methoxyphenyl)-6-methylthieno[2,3-b]pyridine-2-carboxamide675865-07-3C18H19N3O3S
- 3-Amino-N-(2,6-dichlorophenyl)-6-methylthieno[2,3-b]pyridine-2-carboxamide496804-74-1C15H11Cl2N3OS
- 3-Amino-6-methyl-N-[4-(trifluoromethoxy)phenyl]thieno[2,3-b]pyridine-2-carboxamide496804-73-0C16H12F3N3O2S
- 3-Amino-N-(2,6-dichlorophenyl)-6-methyl-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide445382-74-1C16H10Cl2F3N3OS
- 3-Amino-N-(4-fluorophenyl)-4-methyl-6-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide445382-78-5C16H11F4N3OS
- 3-Amino-N-(4-methoxyphenyl)-6-methyl-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide255909-20-7C17H14F3N3O2S
- 3-Amino-N-(2-fluoro-5-methylphenyl)-4-(methoxymethyl)-6-methylthieno[2,3-b]pyridine-2-carboxamide675869-55-3C18H18FN3O2S
- 3-Amino-N-(4-cyanophenyl)-4-(methoxymethyl)-6-methylthieno[2,3-b]pyridine-2-carboxamide797029-44-8C18H16N4O2S
- N-(4-Acetamidophenyl)-3-amino-4-(methoxymethyl)-6-methylthieno[2,3-b]pyridine-2-carboxamide708999-23-9C19H20N4O3S
- 3-Amino-4-(methoxymethyl)-N-(3-methoxyphenyl)-6-methylthieno[2,3-b]pyridine-2-carboxamide708281-69-0C18H19N3O3S
Related scaffolds
Same ring framework with different atoms or bond orders
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