Murcko scaffold
Ring system with 2 rings and 9 atoms
151 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 151
- With full pages
- 28
Scaffold SMILES
O=C1CC2SCC=CN12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 151 chemicals
7-Amino-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
CAS 26395-99-3C8H10N2O3S
3-((Acetyloxy)methyl)-7-amino-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
CAS 68090-55-1C10H12N2O5S
7-Aminodeacetoxycephalosporanic acid
CAS 22252-43-3C8H10N2O3S
![7-Amino-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid chemical structure, C7H7ClN2O3S, CAS 108260-01-1](/s/OQSAFIZCBAZPMY-UHFFFAOYSA-N.svg)
7-Amino-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS 108260-01-1C7H7ClN2O3S
Cephalosporin C
CAS 61-24-5C16H21N3O8S
Cefacetrile
CAS 10206-21-0C13H13N3O6S
(6R-Trans)-3-(Acetoxymethyl)-7-((4-chloro-1,3-dioxobutyl)amino)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
CAS 58684-54-1C14H15ClN2O7S
![3-[(Acetyloxy)methyl]-7-amino-7-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid chemical structure, C11H14N2O6S, CAS 54083-02-2](/s/RFTYZLNBEGIZRP-UHFFFAOYSA-N.svg)
3-[(Acetyloxy)methyl]-7-amino-7-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS 54083-02-2C11H14N2O6S
(Pivaloyloxy)methyl (6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate
CAS 27726-32-5C14H20N2O5S
5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-(((aminocarbonyl)oxy)methyl)-7-((5-amino-5-carboxy-1-oxopentyl)amino)-7-methoxy-8-oxo-
CAS 38429-35-5C16H22N4O9S
Chitinovorin C
CAS 95230-98-1C15H20N4O8S
7beta-(5-Hydroxy-5-carboxyvarelamido)-3-hydroxymethyl-3-cephem-4-carboxylic acid
CAS 85416-37-1C14H18N2O8S
Deacetoxycephalosporin C
CAS 26924-74-3C14H19N3O6S
Deacetylcephalosporin C
CAS 1476-46-6C14H19N3O7S
7-Methoxycephalosporin C
CAS 41849-38-1C17H23N3O9S
SF 1623
CAS 56487-86-6C15H21N3O10S3
SF 1623B
CAS 58301-37-4C15H21N3O8S
O-Carbamoyl-deacetylcephalosporin C
CAS 60831-57-4C15H20N4O8S
![3-(Acetyloxymethyl)-7-[[2-(N,N'-diethylcarbamimidoyl)sulfanylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid chemical structure, C17H24N4O6S2, CAS 33074-98-5](/s/QGIQVDXCNNPRCE-UHFFFAOYSA-N.svg)
3-(Acetyloxymethyl)-7-[[2-(N,N'-diethylcarbamimidoyl)sulfanylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS 33074-98-5C17H24N4O6S2
Cephamycin C
CAS 34279-51-1C16H22N4O9S
7-Aminocephalosporanic acid
CAS 957-68-6C10H12N2O5S
Glutaryl-7-aminocephalosporanic acid
CAS 27920-90-7C15H18N2O8S
Cephalosporin C sodium salt
C16H20N3NaO8S
![(6S,7S)-7-Amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid chemical structure, C8H10N2O3S, CAS 70287-30-8](/s/NVIAYEIXYQCDAN-FFWSUHOLSA-N.svg)
(6S,7S)-7-Amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS 70287-30-8C8H10N2O3S
- Cephabacin M699313-73-2C47H79N13O18S
- Cephabacin M499313-74-3C41H69N11O15S
- Cephabacin M399313-75-4C37H60N10O16S
- Cephabacin M299313-76-5C34H55N9O15S
- Cephabacin M599332-95-3C44H74N12O17S
- Cephabacin M199332-96-4C31H50N8O13S
- 7-[(5-Acetamido-5-carboxypentanoyl)amino]-3-[[4-[[(2S)-1-[[(2S)-2-[[(2S)-2-acetamidopropanoyl]amino]propanoyl]amino]-1-oxopropan-2-yl]amino]-7-(diaminomethylideneamino)-3-hydroxyheptanoyl]oxymethyl]-7-formamido-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid92121-46-5C36H55N11O15S
- SQ 2851792131-67-4C36H56N12O14S
- Antibiotic tan-592B99685-75-3C29H47ClN10O14S
- Cephalexin impurity 928242-91-3C14H16N2O8S
- (6R,7R)-7-[(4-Carboxy-1-oxobutyl)amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid60758-77-2C13H16N2O6S
- (6R-(6Alpha,7beta(R*)))-3-(acetoxymethyl)-7-((5-amino-5-carboxypentanoyl)amino)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, zinc salt41279-77-0C16H19N3O8SZn
- (6R-Trans)-3-(Acetoxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, mono(toluene-p-sulphonate)5203-31-6C17H20N2O8S2
- Cyanocef53726-29-7C12H13N3O4S2
- (6R,7R)-7-((4-Carboxy-1-oxobutyl)amino)-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid55779-10-7C13H16N2O7S
- 7-(5-Carboxyvaleramido)-7-methoxycephalosporanic acid56348-70-0C17H22N2O9S
- (Pivaloyloxy)methyl (6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate monohydrochloride57184-01-7C14H21ClN2O5S
- Potassium (6R,7R)-3-acetoxymethyl-7-(D-5-amino-5-carboxypentanamido)-ceph-3-em-4-carboxylic acid26944-38-7C16H19K2N3O8S
- (6R,7S)-7-Amino-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid108260-07-7C7H7ClN2O3S
- 3 suppliers7-Amino-3-chloro-3-cephem-4-carboxylic acid53994-69-7C7H7ClN2O3S
- (6R,7S)-7-Amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid72059-35-9C8H10N2O3S
- 11 suppliers(6R,7R)-7-Amino-8-oxo-3-vinyl-5-thia-1-aza-bicyclo(4,2,0)oct-2-ene-2-carboxylic acid79349-82-9C9H10N2O3S
- 3 suppliers(6R,7R)-7-Amino-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid24701-69-7C9H12N2O4S
- Ceftiguanide28240-16-6C12H13ClN2O6S
Related scaffolds
Same ring framework with different atoms or bond orders
