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Murcko scaffold

Bicyclo[4.2.0]octane scaffold

84 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
8
Chemicals
84
With full pages
6
Scaffold SMILES

C1CCC2CCC2C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Bicyclo[4.2.0]octane page
Murcko scaffold C1CCC2CCC2C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 84 chemicals

Bicyclo[4.2.0]octane chemical structure, C8H14, CAS 278-30-8
Bicyclo[4.2.0]octane
CAS 278-30-8C8H14
7-Methylbicyclo[4.2.0]octane chemical structure, C9H16, CAS 1005240-14-1
7-Methylbicyclo[4.2.0]octane
CAS 1005240-14-1C9H16
Bicyclo(4.2.0)octane, trans- chemical structure, C8H14, CAS 63296-41-3
Bicyclo(4.2.0)octane, trans-
CAS 63296-41-3C8H14
cis-Bicyclo(4.2.0)octane chemical structure, C8H14, CAS 28282-35-1
cis-Bicyclo(4.2.0)octane
CAS 28282-35-1C8H14
4,4,6-Trimethylbicyclo[4.2.0]octan-2-ol chemical structure, C11H20O, CAS 64394-17-8
4,4,6-Trimethylbicyclo[4.2.0]octan-2-ol
CAS 64394-17-8C11H20O
1-Propanone, 1-[6-[(trimethylsilyl)methyl]bicyclo[4.2.0]oct-7-yl]- chemical structure, C15H28OSi, CAS 144463-93-4
1-Propanone, 1-[6-[(trimethylsilyl)methyl]bicyclo[4.2.0]oct-7-yl]-
CAS 144463-93-4C15H28OSi
2-[(1R,6R,7S)-7-(Aminomethyl)-7-bicyclo[4.2.0]octanyl]acetic acid chemical structure, C11H19NO2, CAS 473829-39-9
2-[(1R,6R,7S)-7-(Aminomethyl)-7-bicyclo[4.2.0]octanyl]acetic acid
CAS 473829-39-9C11H19NO2
(1R,6S,8S)-8-(Hydroxymethyl)bicyclo[4.2.0]octan-1-ol chemical structure, C9H16O2, CAS 657428-65-4
(1R,6S,8S)-8-(Hydroxymethyl)bicyclo[4.2.0]octan-1-ol
CAS 657428-65-4C9H16O2
4,4,6-Trimethylbicyclo(4.2.0)oct-2-yl acetate chemical structure, C13H22O2, CAS 94022-62-5
4,4,6-Trimethylbicyclo(4.2.0)oct-2-yl acetate
CAS 94022-62-5C13H22O2
Bicyclo[4.2.0]octane-7-carboxamide chemical structure, C9H15NO, CAS 90693-50-8
Bicyclo[4.2.0]octane-7-carboxamide
CAS 90693-50-8C9H15NO
Bicyclo[4.2.0]octane-7-carboxylic acid chemical structure, C9H14O2, CAS 105118-52-3
Bicyclo[4.2.0]octane-7-carboxylic acid
CAS 105118-52-3C9H14O2
3,4-Dibromo-3,4-dichlorobicyclo[4.2.0]octane-7,8-dicarboxylic acid chemical structure, C10H10Br2Cl2O4, CAS 62814-86-2
3,4-Dibromo-3,4-dichlorobicyclo[4.2.0]octane-7,8-dicarboxylic acid
CAS 62814-86-2C10H10Br2Cl2O4
{Bicyclo[4.2.0]octan-7-yl}methanamine chemical structure, C9H17N, CAS 1783417-50-4
{Bicyclo[4.2.0]octan-7-yl}methanamine
CAS 1783417-50-4C9H17N
8,8-Dimethylbicyclo[4.2.0]octan-7-amine chemical structure, C10H19N, CAS 1559883-33-8
8,8-Dimethylbicyclo[4.2.0]octan-7-amine
CAS 1559883-33-8C10H19N
Bicyclo[4.2.0]octan-7-amine chemical structure, C8H15N, CAS 1559840-55-9
Bicyclo[4.2.0]octan-7-amine
CAS 1559840-55-9C8H15N
2-{Bicyclo[4.2.0]octan-7-yl}ethan-1-amine chemical structure, C10H19N, CAS 1780655-85-7
2-{Bicyclo[4.2.0]octan-7-yl}ethan-1-amine
CAS 1780655-85-7C10H19N
2-{Bicyclo[4.2.0]octan-7-yl}acetonitrile chemical structure, C10H15N, CAS 1781002-40-1
2-{Bicyclo[4.2.0]octan-7-yl}acetonitrile
CAS 1781002-40-1C10H15N
rac-(1R,6R,7S)-Bicyclo[4.2.0]octan-7-amine chemical structure, C8H15N, CAS 2089245-78-1
rac-(1R,6R,7S)-Bicyclo[4.2.0]octan-7-amine
CAS 2089245-78-1C8H15N
(1S,6S,7R)-Bicyclo[4.2.0]octan-7-amine hydrochloride chemical structure, C8H16ClN, CAS 2089245-79-2
(1S,6S,7R)-Bicyclo[4.2.0]octan-7-amine hydrochloride
CAS 2089245-79-2C8H16ClN
rel-(1R,6S,7R)-6-Hydroxybicyclo[4.2.0]octane-7-methanol chemical structure, C9H16O2
rel-(1R,6S,7R)-6-Hydroxybicyclo[4.2.0]octane-7-methanol
C9H16O2
rac-((1R,6R,7S)-Bicyclo(4.2.0)octan-7-yl)methanesulfonyl chloride chemical structure, C9H15ClO2S, CAS 2138010-79-2
rac-((1R,6R,7S)-Bicyclo(4.2.0)octan-7-yl)methanesulfonyl chloride
CAS 2138010-79-2C9H15ClO2S
Bicyclo[4.2.0]octan-7-amine hydrochloride chemical structure, C8H16ClN, CAS 2089258-60-4
Bicyclo[4.2.0]octan-7-amine hydrochloride
CAS 2089258-60-4C8H16ClN
[(1S,6S,7R)-7-Bicyclo[4.2.0]octanyl]methanesulfonyl fluoride chemical structure, C9H15FO2S, CAS 2287247-88-3
[(1S,6S,7R)-7-Bicyclo[4.2.0]octanyl]methanesulfonyl fluoride
CAS 2287247-88-3C9H15FO2S
[(1R,6S,7S,8S)-8-Amino-7-bicyclo[4.2.0]octanyl]methanol, hydrochloride chemical structure, C9H18ClNO, CAS 2309431-28-3
[(1R,6S,7S,8S)-8-Amino-7-bicyclo[4.2.0]octanyl]methanol, hydrochloride
CAS 2309431-28-3C9H18ClNO