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Murcko scaffold

Benzocyclobutene scaffold

364 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
8
Chemicals
364
With full pages
35
Scaffold SMILES

c1ccc2c(c1)CC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Benzocyclobutene page
Murcko scaffold c1ccc2c(c1)CC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 364 chemicals

Ketone, bicyclo(4.2.0)octa-1,3,5-trien-7-yl methyl chemical structure, C10H10O, CAS 1075-30-5
Ketone, bicyclo(4.2.0)octa-1,3,5-trien-7-yl methyl
CAS 1075-30-5C10H10O
1-Bicyclo(4.2.0)octa-1,3,5-trien-7-yl-1-pentanone chemical structure, C13H16O, CAS 6809-93-4
1-Bicyclo(4.2.0)octa-1,3,5-trien-7-yl-1-pentanone
CAS 6809-93-4C13H16O
[1-(7-Bicyclo[4.2.0]octa-1,3,5-trienyl)ethylideneamino] acetate chemical structure, C12H13NO2
[1-(7-Bicyclo[4.2.0]octa-1,3,5-trienyl)ethylideneamino] acetate
C12H13NO2
1-Bicyclo(4.2.0)octa-1,3,5-trien-7-ylethanone O-butyloxime chemical structure, C14H19NO, CAS 7315-27-7
1-Bicyclo(4.2.0)octa-1,3,5-trien-7-ylethanone O-butyloxime
CAS 7315-27-7C14H19NO
Benzocyclobutene chemical structure, C8H8, CAS 694-87-1
Benzocyclobutene
CAS 694-87-1C8H8
1-Benzocyclobutenecarbonitrile chemical structure, C9H7N, CAS 6809-91-2
1-Benzocyclobutenecarbonitrile
CAS 6809-91-2C9H7N
7,8-Diiodobicyclo[4.2.0]octa-1,3,5-triene chemical structure, C8H6I2, CAS 6639-21-0
7,8-Diiodobicyclo[4.2.0]octa-1,3,5-triene
CAS 6639-21-0C8H6I2
8,8-Dichloro-2,4-dimethylbicyclo(4.2.0)octa-1,3,5-triene chemical structure, C10H10Cl2, CAS 6590-38-1
8,8-Dichloro-2,4-dimethylbicyclo(4.2.0)octa-1,3,5-triene
CAS 6590-38-1C10H10Cl2
3,7,7-Trichloro-2,4,5-trimethylbicyclo[4.2.0]octa-1,3,5-triene chemical structure, C11H11Cl3, CAS 6590-37-0
3,7,7-Trichloro-2,4,5-trimethylbicyclo[4.2.0]octa-1,3,5-triene
CAS 6590-37-0C11H11Cl3
2,3,4,5-Tetramethylbicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile chemical structure, C13H15N, CAS 6670-38-8
2,3,4,5-Tetramethylbicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile
CAS 6670-38-8C13H15N
Bicyclo[4.2.0]octa-1,3,5-triene-7,8-diyl diacetate chemical structure, C12H12O4, CAS 52679-84-2
Bicyclo[4.2.0]octa-1,3,5-triene-7,8-diyl diacetate
CAS 52679-84-2C12H12O4
Bicyclo[4.2.0]octa-1,3,5-triene, 7,7-dichloro- chemical structure, C8H6Cl2, CAS 68913-13-3
Bicyclo[4.2.0]octa-1,3,5-triene, 7,7-dichloro-
CAS 68913-13-3C8H6Cl2
Bicyclo[4.2.0]octa-1,3,5-trien-7-yl acetate chemical structure, C10H10O2, CAS 3469-03-2
Bicyclo[4.2.0]octa-1,3,5-trien-7-yl acetate
CAS 3469-03-2C10H10O2
7-Ethoxybicyclo[4.2.0]octa-1,3,5-triene chemical structure, C10H12O, CAS 3718-75-0
7-Ethoxybicyclo[4.2.0]octa-1,3,5-triene
CAS 3718-75-0C10H12O
Methyl 7,7-dimethyl-5-nitrobicyclo[4.2.0]octa-1,3,5-triene-3-carboxylate chemical structure, C12H13NO4, CAS 28538-61-6
Methyl 7,7-dimethyl-5-nitrobicyclo[4.2.0]octa-1,3,5-triene-3-carboxylate
CAS 28538-61-6C12H13NO4
3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile chemical structure, C11H11NO2, CAS 35202-54-1
3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile
CAS 35202-54-1C11H11NO2
N-(3,5-Dimethylbicyclo(4.2.0)octa-1,3,5-trien-7-yl)propanamide chemical structure, C13H17NO, CAS 33213-02-4
N-(3,5-Dimethylbicyclo(4.2.0)octa-1,3,5-trien-7-yl)propanamide
CAS 33213-02-4C13H17NO
Ethyl N-(2,4-dimethyl-8-bicyclo[4.2.0]octa-1,3,5-trienyl)carbamate chemical structure, C13H17NO2, CAS 33213-06-8
Ethyl N-(2,4-dimethyl-8-bicyclo[4.2.0]octa-1,3,5-trienyl)carbamate
CAS 33213-06-8C13H17NO2
N-(3,5-Dimethylbicyclo(4.2.0)octa-1,3,5-trien-7-yl)butanamide chemical structure, C14H19NO, CAS 33213-03-5
N-(3,5-Dimethylbicyclo(4.2.0)octa-1,3,5-trien-7-yl)butanamide
CAS 33213-03-5C14H19NO
Bicyclo(4.2.0)octa-1,3,5-triene-7-carboxylic acid chemical structure, C9H8O2, CAS 14381-41-0
Bicyclo(4.2.0)octa-1,3,5-triene-7-carboxylic acid
CAS 14381-41-0C9H8O2
N-(3,5-Dimethylbicyclo[4.2.0]octa-1,3,5-trien-7-yl)acetamide chemical structure, C12H15NO, CAS 33213-01-3
N-(3,5-Dimethylbicyclo[4.2.0]octa-1,3,5-trien-7-yl)acetamide
CAS 33213-01-3C12H15NO
2,3,4,5-Tetramethyl-bicyclo(4.2.0)octa-1(6),2,4-trien-7-ol chemical structure, C12H16O, CAS 6670-39-9
2,3,4,5-Tetramethyl-bicyclo(4.2.0)octa-1(6),2,4-trien-7-ol
CAS 6670-39-9C12H16O
(3,4-Dimethoxy-bicyclo[4.2.0]octa-1,3,5-trien-7-yl)-methylamine chemical structure, C11H15NO2, CAS 73344-75-9
(3,4-Dimethoxy-bicyclo[4.2.0]octa-1,3,5-trien-7-yl)-methylamine
CAS 73344-75-9C11H15NO2
3,5-Dimethylbicyclo[4.2.0]octa-1,3,5-trien-7-amine chemical structure, C10H13N, CAS 32304-33-9
3,5-Dimethylbicyclo[4.2.0]octa-1,3,5-trien-7-amine
CAS 32304-33-9C10H13N