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Murcko scaffold

Ring system with 2 rings and 8 atoms

43 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
8
Chemicals
43
With full pages
4
Scaffold SMILES

C1COC2CCC2C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C1COC2CCC2C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 43 of 43 chemicals

8,8-Dimethyl-2-oxabicyclo[4.2.0]octan-7-ol chemical structure, C9H16O2, CAS 90646-73-4
8,8-Dimethyl-2-oxabicyclo[4.2.0]octan-7-ol
CAS 90646-73-4C9H16O2
8,8-Dimethyl-2-oxabicyclo(4.2.0)octan-7-amine chemical structure, C9H17NO, CAS 1342540-54-8
8,8-Dimethyl-2-oxabicyclo(4.2.0)octan-7-amine
CAS 1342540-54-8C9H17NO
7-Amino-8,8-dimethyl-2-oxabicyclo[4.2.0]octane-7-carboxylic acid hydrochloride chemical structure, C10H18ClNO3, CAS 1797798-82-3
7-Amino-8,8-dimethyl-2-oxabicyclo[4.2.0]octane-7-carboxylic acid hydrochloride
CAS 1797798-82-3C10H18ClNO3
7-{[(tert-Butoxy)carbonyl]amino}-8,8-dimethyl-2-oxabicyclo[4.2.0]octane-7-carboxylic acid chemical structure, C15H25NO5, CAS 1797019-22-7
7-{[(tert-Butoxy)carbonyl]amino}-8,8-dimethyl-2-oxabicyclo[4.2.0]octane-7-carboxylic acid
CAS 1797019-22-7C15H25NO5
2-Oxabicyclo[4.2.0]octan-7-amine hydrochloride chemical structure, C7H14ClNO, CAS 1797303-39-9
2-Oxabicyclo[4.2.0]octan-7-amine hydrochloride
CAS 1797303-39-9C7H14ClNO
2-Oxabicyclo[4.2.0]octan-7-amine chemical structure, C7H13NO, CAS 1782417-94-0
2-Oxabicyclo[4.2.0]octan-7-amine
CAS 1782417-94-0C7H13NO
2-Oxabicyclo[4.2.0]octan-7-ol chemical structure, C7H12O2, CAS 1779808-37-5
2-Oxabicyclo[4.2.0]octan-7-ol
CAS 1779808-37-5C7H12O2
rac-(1R,6S,7S)-2-Oxabicyclo[4.2.0]octan-7-amine chemical structure, C7H13NO, CAS 2173996-82-0
rac-(1R,6S,7S)-2-Oxabicyclo[4.2.0]octan-7-amine
CAS 2173996-82-0C7H13NO
rac-(1R,6S,7S)-2-Oxabicyclo[4.2.0]octan-7-amine hydrochloride chemical structure, C7H14ClNO, CAS 2173996-83-1
rac-(1R,6S,7S)-2-Oxabicyclo[4.2.0]octan-7-amine hydrochloride
CAS 2173996-83-1C7H14ClNO
N-{2-Oxabicyclo[4.2.0]octan-7-yl}prop-2-enamide chemical structure, C10H15NO2, CAS 2224287-91-4
N-{2-Oxabicyclo[4.2.0]octan-7-yl}prop-2-enamide
CAS 2224287-91-4C10H15NO2
rac-(1R,6S)-2-Oxabicyclo[4.2.0]octan-7-amine hydrochloride chemical structure, C7H14ClNO, CAS 2173992-59-9
rac-(1R,6S)-2-Oxabicyclo[4.2.0]octan-7-amine hydrochloride
CAS 2173992-59-9C7H14ClNO
rac-(1R,6S)-2-Oxabicyclo[4.2.0]octan-7-amine chemical structure, C7H13NO, CAS 2138655-67-9
rac-(1R,6S)-2-Oxabicyclo[4.2.0]octan-7-amine
CAS 2138655-67-9C7H13NO
tert-Butyl 7-amino-8,8-dimethyl-2-oxabicyclo[4.2.0]octane-7-carboxylate chemical structure, C14H25NO3, CAS 2248314-83-0
tert-Butyl 7-amino-8,8-dimethyl-2-oxabicyclo[4.2.0]octane-7-carboxylate
CAS 2248314-83-0C14H25NO3
(1S,6R,7R)-7-[(2-Methylpropan-2-yl)oxycarbonylamino]-2-oxabicyclo[4.2.0]octane-7-carboxylic acid chemical structure, C13H21NO5, CAS 2567488-98-4
(1S,6R,7R)-7-[(2-Methylpropan-2-yl)oxycarbonylamino]-2-oxabicyclo[4.2.0]octane-7-carboxylic acid
CAS 2567488-98-4C13H21NO5
Chloromethyl 7-{[(tert-butoxy)carbonyl]amino}-8,8-dimethyl-2-oxabicyclo[4.2.0]octane-7-carboxylate chemical structure, C16H26ClNO5, CAS 2137740-95-3
Chloromethyl 7-{[(tert-butoxy)carbonyl]amino}-8,8-dimethyl-2-oxabicyclo[4.2.0]octane-7-carboxylate
CAS 2137740-95-3C16H26ClNO5
2-{7-Amino-2-oxabicyclo[4.2.0]octan-7-yl}acetamide chemical structure, C9H16N2O2, CAS 2172233-42-8
2-{7-Amino-2-oxabicyclo[4.2.0]octan-7-yl}acetamide
CAS 2172233-42-8C9H16N2O2
rac-(1R,6R)-2-Oxabicyclo[4.2.0]octane-7-sulfonyl chloride chemical structure, C7H11ClO3S, CAS 2228021-56-3
rac-(1R,6R)-2-Oxabicyclo[4.2.0]octane-7-sulfonyl chloride
CAS 2228021-56-3C7H11ClO3S
2-Oxabicyclo[4.2.0]octane-7-thiol chemical structure, C7H12OS, CAS 2172343-34-7
2-Oxabicyclo[4.2.0]octane-7-thiol
CAS 2172343-34-7C7H12OS
2-{7-Amino-2-oxabicyclo[4.2.0]octan-7-yl}acetic acid chemical structure, C9H15NO3, CAS 2172495-05-3
2-{7-Amino-2-oxabicyclo[4.2.0]octan-7-yl}acetic acid
CAS 2172495-05-3C9H15NO3
2-(7-{[(tert-Butoxy)carbonyl]amino}-2-oxabicyclo[4.2.0]octan-7-yl)acetic acid chemical structure, C14H23NO5, CAS 2172110-82-4
2-(7-{[(tert-Butoxy)carbonyl]amino}-2-oxabicyclo[4.2.0]octan-7-yl)acetic acid
CAS 2172110-82-4C14H23NO5
2-Oxabicyclo[4.2.0]octane-7-sulfonyl fluoride chemical structure, C7H11FO3S, CAS 2171969-70-1
2-Oxabicyclo[4.2.0]octane-7-sulfonyl fluoride
CAS 2171969-70-1C7H11FO3S
1-{7-Methoxy-2-oxabicyclo[4.2.0]octan-7-yl}methanamine chemical structure, C9H17NO2, CAS 2171688-13-2
1-{7-Methoxy-2-oxabicyclo[4.2.0]octan-7-yl}methanamine
CAS 2171688-13-2C9H17NO2
Methyl 7-amino-8,8-dimethyl-2-oxabicyclo[4.2.0]octane-7-carboxylate chemical structure, C11H19NO3, CAS 2167441-35-0
Methyl 7-amino-8,8-dimethyl-2-oxabicyclo[4.2.0]octane-7-carboxylate
CAS 2167441-35-0C11H19NO3
rac-(1R,6R)-2-Oxabicyclo[4.2.0]octane-7-sulfonyl fluoride chemical structure, C7H11FO3S, CAS 2228052-44-4
rac-(1R,6R)-2-Oxabicyclo[4.2.0]octane-7-sulfonyl fluoride
CAS 2228052-44-4C7H11FO3S