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Murcko scaffold

Benzocyclobutanone scaffold

52 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
52
With full pages
7
Scaffold SMILES

O=C1Cc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Benzocyclobutanone page
Murcko scaffold O=C1Cc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 52 chemicals

Benzocyclobutanone chemical structure, C8H6O, CAS 3469-06-5
Benzocyclobutanone
CAS 3469-06-5C8H6O
2,3,4,5-Tetramethylbicyclo(4.2.0)octa-1,3,5-trien-7-one chemical structure, C12H14O, CAS 6590-36-9
2,3,4,5-Tetramethylbicyclo(4.2.0)octa-1,3,5-trien-7-one
CAS 6590-36-9C12H14O
3,5-Dimethylbicyclo[4.2.0]octa-1,3,5-trien-7-one chemical structure, C10H10O, CAS 6670-28-6
3,5-Dimethylbicyclo[4.2.0]octa-1,3,5-trien-7-one
CAS 6670-28-6C10H10O
Bicyclo[4.2.0]octa-1,3,5-trien-7-one, 3-methyl- chemical structure, C9H8O, CAS 126889-61-0
Bicyclo[4.2.0]octa-1,3,5-trien-7-one, 3-methyl-
CAS 126889-61-0C9H8O
Bicyclo[4.2.0]octa-1,3,5-trien-7-one, 4-methyl- chemical structure, C9H8O, CAS 62708-43-4
Bicyclo[4.2.0]octa-1,3,5-trien-7-one, 4-methyl-
CAS 62708-43-4C9H8O
5-Methoxybicyclo[4.2.0]octa-1,3,5-trien-7-one chemical structure, C9H8O2, CAS 66947-60-2
5-Methoxybicyclo[4.2.0]octa-1,3,5-trien-7-one
CAS 66947-60-2C9H8O2
3-Methoxybicyclo(4.2.0)octa-1,3,5-trien-7-one chemical structure, C9H8O2, CAS 22246-27-1
3-Methoxybicyclo(4.2.0)octa-1,3,5-trien-7-one
CAS 22246-27-1C9H8O2
Bicyclo[4.2.0]octa-1,3,5-trien-7-one, 4-methoxy- chemical structure, C9H8O2, CAS 55171-77-2
Bicyclo[4.2.0]octa-1,3,5-trien-7-one, 4-methoxy-
CAS 55171-77-2C9H8O2
Bicyclo[4.2.0]octa-1,3,5-trien-7-one, 2-bromo-5-methoxy- chemical structure, C9H7BrO2, CAS 54639-86-0
Bicyclo[4.2.0]octa-1,3,5-trien-7-one, 2-bromo-5-methoxy-
CAS 54639-86-0C9H7BrO2
4-Bromo-5-methoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-one chemical structure, C9H7BrO2, CAS 203805-64-5
4-Bromo-5-methoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-one
CAS 203805-64-5C9H7BrO2
2,5-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-one chemical structure, C10H10O3, CAS 75833-45-3
2,5-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-one
CAS 75833-45-3C10H10O3
3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-one chemical structure, C10H10O3, CAS 55171-76-1
3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-one
CAS 55171-76-1C10H10O3
5-Fluorobicyclo(4.2.0)octa-1(6),2,4-trien-7-one chemical structure, C8H5FO, CAS 118112-20-2
5-Fluorobicyclo(4.2.0)octa-1(6),2,4-trien-7-one
CAS 118112-20-2C8H5FO
5-Chlorobicyclo(4.2.0)octa-1,3,5-trien-7-one chemical structure, C8H5ClO, CAS 81447-63-4
5-Chlorobicyclo(4.2.0)octa-1,3,5-trien-7-one
CAS 81447-63-4C8H5ClO
5-Bromobicyclo[4.2.0]octa-1(6),2,4-trien-7-one chemical structure, C8H5BrO, CAS 203805-65-6
5-Bromobicyclo[4.2.0]octa-1(6),2,4-trien-7-one
CAS 203805-65-6C8H5BrO
8-Oxobicyclo[4.2.0]octa-1(6),2,4-triene-2-carbonitrile chemical structure, C9H5NO, CAS 203805-69-0
8-Oxobicyclo[4.2.0]octa-1(6),2,4-triene-2-carbonitrile
CAS 203805-69-0C9H5NO
Bicyclo[4.2.0]octa-1,3,5-trien-7-one, 8-chloro- chemical structure, C8H5ClO, CAS 89185-28-4
Bicyclo[4.2.0]octa-1,3,5-trien-7-one, 8-chloro-
CAS 89185-28-4C8H5ClO
8-Bromobicyclo(4.2.0)octa-1,3,5-trien-7-one chemical structure, C8H5BrO, CAS 934-01-0
8-Bromobicyclo(4.2.0)octa-1,3,5-trien-7-one
CAS 934-01-0C8H5BrO
4-Fluorobicyclo(4.2.0)octa-1(6),2,4-trien-7-one chemical structure, C8H5FO, CAS 409060-44-2
4-Fluorobicyclo(4.2.0)octa-1(6),2,4-trien-7-one
CAS 409060-44-2C8H5FO
Bicyclo[4.2.0]octa-1,3,5-trien-7-one, 5,8,8-trimethoxy- chemical structure, C11H12O4, CAS 211108-80-4
Bicyclo[4.2.0]octa-1,3,5-trien-7-one, 5,8,8-trimethoxy-
CAS 211108-80-4C11H12O4
Bicyclo[4.2.0]octa-1,3,5-trien-7-one, 8-(trimethylsilyl)- chemical structure, C11H14OSi, CAS 78752-32-6
Bicyclo[4.2.0]octa-1,3,5-trien-7-one, 8-(trimethylsilyl)-
CAS 78752-32-6C11H14OSi
Bicyclo[4.2.0]octa-1,3,5-trien-7-one, 8-hydroxy-5-methoxy- chemical structure, C9H8O3, CAS 314280-54-1
Bicyclo[4.2.0]octa-1,3,5-trien-7-one, 8-hydroxy-5-methoxy-
CAS 314280-54-1C9H8O3
Bicyclo[4.2.0]octa-1,3,5-trien-7-one, 2,8,8-trimethoxy- chemical structure, C11H12O4, CAS 314280-53-0
Bicyclo[4.2.0]octa-1,3,5-trien-7-one, 2,8,8-trimethoxy-
CAS 314280-53-0C11H12O4
Bicyclo[4.2.0]octa-1,3,5-trien-7-one, 4-amino- chemical structure, C8H7NO, CAS 197632-56-7
Bicyclo[4.2.0]octa-1,3,5-trien-7-one, 4-amino-
CAS 197632-56-7C8H7NO