Murcko scaffold
3,8-Diazabicyclo[4.2.0]octane scaffold
42 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 8
- Chemicals
- 42
- With full pages
- 4
Scaffold SMILES
C1CC2CNC2CN1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 42 of 42 chemicals
rac-tert-Butyl (1R,6S)-3,8-diazabicyclo(4.2.0)octane-8-carboxylate
CAS 370881-00-8C11H20N2O2
![(1S,6R)-8-Boc-3,8-diazabicyclo[4.2.0]octane chemical structure, C11H20N2O2, CAS 851526-80-2](/s/ITVHTQLHEQGQNG-RKDXNWHRSA-N.svg)
(1S,6R)-8-Boc-3,8-diazabicyclo[4.2.0]octane
CAS 851526-80-2C11H20N2O2
![cis-3-Boc-3,8-diazabicyclo[4.2.0]octane chemical structure, C11H20N2O2, CAS 370882-99-8](/s/VGJOEEIXDPWTAZ-IUCAKERBSA-N.svg)
cis-3-Boc-3,8-diazabicyclo[4.2.0]octane
CAS 370882-99-8C11H20N2O2
![(1S,6R)-3-Boc-3,8-diazabicyclo[4.2.0]octane chemical structure, C11H20N2O2, CAS 370881-96-2](/s/VGJOEEIXDPWTAZ-RKDXNWHRSA-N.svg)
(1S,6R)-3-Boc-3,8-diazabicyclo[4.2.0]octane
CAS 370881-96-2C11H20N2O2
![3,8-Diazabicyclo[4.2.0]octane chemical structure, C6H12N2, CAS 83693-76-9](/s/CPGFQLIXICGYSN-UHFFFAOYSA-N.svg)
3,8-Diazabicyclo[4.2.0]octane
CAS 83693-76-9C6H12N2
![tert-Butyl (1S,6S)-3,8-diazabicyclo[4.2.0]octane-3-carboxylate chemical structure, C11H20N2O2, CAS 1932028-07-3](/s/VGJOEEIXDPWTAZ-DTWKUNHWSA-N.svg)
tert-Butyl (1S,6S)-3,8-diazabicyclo[4.2.0]octane-3-carboxylate
CAS 1932028-07-3C11H20N2O2
![tert-Butyl (1R,6R)-3,8-diazabicyclo[4.2.0]octane-3-carboxylate chemical structure, C11H20N2O2, CAS 1932307-89-5](/s/VGJOEEIXDPWTAZ-BDAKNGLRSA-N.svg)
tert-Butyl (1R,6R)-3,8-diazabicyclo[4.2.0]octane-3-carboxylate
CAS 1932307-89-5C11H20N2O2
![tert-Butyl 3,8-diazabicyclo[4.2.0]octane-3-carboxylate chemical structure, C11H20N2O2, CAS 928754-14-7](/s/VGJOEEIXDPWTAZ-UHFFFAOYSA-N.svg)
tert-Butyl 3,8-diazabicyclo[4.2.0]octane-3-carboxylate
CAS 928754-14-7C11H20N2O2
![tert-Butyl 3,8-diazabicyclo[4.2.0]octane-8-carboxylate chemical structure, C11H20N2O2, CAS 848591-80-0](/s/ITVHTQLHEQGQNG-UHFFFAOYSA-N.svg)
tert-Butyl 3,8-diazabicyclo[4.2.0]octane-8-carboxylate
CAS 848591-80-0C11H20N2O2
![(1S,6R)-8-Methyl-3,8-diazabicyclo[4.2.0]octane chemical structure, C7H14N2, CAS 1932278-31-3](/s/UPTIQMLLFYHQPD-RNFRBKRXSA-N.svg)
(1S,6R)-8-Methyl-3,8-diazabicyclo[4.2.0]octane
CAS 1932278-31-3C7H14N2
![3-Methyl-3,8-diaza-bicyclo[4.2.0]octane chemical structure, C7H14N2, CAS 1378254-94-4](/s/FKLSALOSNKEZRE-UHFFFAOYSA-N.svg)
3-Methyl-3,8-diaza-bicyclo[4.2.0]octane
CAS 1378254-94-4C7H14N2
![(1R,6S)-3-Methyl-3,8-diazabicyclo[4.2.0]octane chemical structure, C7H14N2, CAS 1434126-84-7](/s/FKLSALOSNKEZRE-BQBZGAKWSA-N.svg)
(1R,6S)-3-Methyl-3,8-diazabicyclo[4.2.0]octane
CAS 1434126-84-7C7H14N2
![(1S,6R)-3-Methyl-3,8-diazabicyclo[4.2.0]octane chemical structure, C7H14N2, CAS 1434127-03-3](/s/FKLSALOSNKEZRE-RNFRBKRXSA-N.svg)
(1S,6R)-3-Methyl-3,8-diazabicyclo[4.2.0]octane
CAS 1434127-03-3C7H14N2
![(1R,6S)-rel-3-Boc-6-methyl-3,8-diazabicyclo[4.2.0]octane chemical structure, C12H22N2O2, CAS 1523530-37-1](/s/PXSDUVHLZMOBDQ-CABZTGNLSA-N.svg)
(1R,6S)-rel-3-Boc-6-methyl-3,8-diazabicyclo[4.2.0]octane
CAS 1523530-37-1C12H22N2O2
![(1S,6R)-rel-8-Acetyl-3,8-diazabicyclo[4.2.0]octane chemical structure, C8H14N2O, CAS 1268520-07-5](/s/NSZFCGYEVWVLOI-HTQZYQBOSA-N.svg)
(1S,6R)-rel-8-Acetyl-3,8-diazabicyclo[4.2.0]octane
CAS 1268520-07-5C8H14N2O
![1-(3,8-Diazabicyclo[4.2.0]octan-8-yl)ethan-1-one chemical structure, C8H14N2O, CAS 1824106-56-0](/s/NSZFCGYEVWVLOI-UHFFFAOYSA-N.svg)
1-(3,8-Diazabicyclo[4.2.0]octan-8-yl)ethan-1-one
CAS 1824106-56-0C8H14N2O
![8-Methyl-3,8-diaza-bicyclo[4.2.0]octane chemical structure, C7H14N2, CAS 1378258-85-5](/s/UPTIQMLLFYHQPD-UHFFFAOYSA-N.svg)
8-Methyl-3,8-diaza-bicyclo[4.2.0]octane
CAS 1378258-85-5C7H14N2
![rac-(1R,6S)-3,8-Diazabicyclo[4.2.0]octane chemical structure, C6H12N2, CAS 2381365-32-6](/s/CPGFQLIXICGYSN-PHDIDXHHSA-N.svg)
rac-(1R,6S)-3,8-Diazabicyclo[4.2.0]octane
CAS 2381365-32-6C6H12N2
![(1R,6S)-8-Methyl-3,8-diazabicyclo[4.2.0]octane chemical structure, C7H14N2, CAS 1434126-88-1](/s/UPTIQMLLFYHQPD-BQBZGAKWSA-N.svg)
(1R,6S)-8-Methyl-3,8-diazabicyclo[4.2.0]octane
CAS 1434126-88-1C7H14N2
![tert-Butyl 7-methyl-3,8-diazabicyclo[4.2.0]octane-3-carboxylate chemical structure, C12H22N2O2, CAS 1438241-09-8](/s/WQOAVSYOMGNWAT-UHFFFAOYSA-N.svg)
tert-Butyl 7-methyl-3,8-diazabicyclo[4.2.0]octane-3-carboxylate
CAS 1438241-09-8C12H22N2O2
![tert-Butyl 1-methyl-3,8-diazabicyclo[4.2.0]octane-3-carboxylate chemical structure, C12H22N2O2, CAS 1438241-17-8](/s/RXGWRXYPDLNXMB-UHFFFAOYSA-N.svg)
tert-Butyl 1-methyl-3,8-diazabicyclo[4.2.0]octane-3-carboxylate
CAS 1438241-17-8C12H22N2O2
![cis-Oxalic acid bis(tert-butyl-3,8-diazabicyclo[4.2.0]octane-8-carboxylate) chemical structure, C24H42N4O8, CAS 1818847-25-4](/s/LVWAGVXLGGSOEA-LVAJUWGCSA-N.svg)
cis-Oxalic acid bis(tert-butyl-3,8-diazabicyclo[4.2.0]octane-8-carboxylate)
CAS 1818847-25-4C24H42N4O8
![tert-Butyl 6-methyl-3,8-diazabicyclo[4.2.0]octane-3-carboxylate chemical structure, C12H22N2O2, CAS 1427385-51-0](/s/PXSDUVHLZMOBDQ-UHFFFAOYSA-N.svg)
tert-Butyl 6-methyl-3,8-diazabicyclo[4.2.0]octane-3-carboxylate
CAS 1427385-51-0C12H22N2O2
![Neopentyl 3,8-diazabicyclo[4.2.0]octane-3-carboxylate chemical structure, C12H22N2O2, CAS 1822802-72-1](/s/RLOYSVWUHHDAHV-UHFFFAOYSA-N.svg)
Neopentyl 3,8-diazabicyclo[4.2.0]octane-3-carboxylate
CAS 1822802-72-1C12H22N2O2
- 8-Methyl-3,8-diazabicyclo[4.2.0]octane, bis(trifluoroacetic acid)2007924-92-5C11H16F6N2O4
- tert-Butyl 3,8-diazabicyclo[4.2.0]octane-3-carboxylate hydrochloride2007925-05-3C11H21ClN2O2
- rac-tert-Butyl (1R,6S)-3,8-diazabicyclo[4.2.0]octane-8-carboxylate trifluoroacetate2137838-84-5C13H21F3N2O4
- 3-Methyl-3,8-diazabicyclo[4.2.0]octane, bis(trifluoroacetic acid)2173083-55-9C11H16F6N2O4
- (1S,6R)-8-Methyl-3,8-diazabicyclo[4.2.0]octane dihydrochloride2221988-52-7C7H16Cl2N2
- (1R,6S)-3-Methyl-3,8-diazabicyclo[4.2.0]octane dihydrochloride2227199-19-9C7H16Cl2N2
- 8-Methyl-3,8-diazabicyclo[4.2.0]octane dihydrochloride2913268-29-6C7H16Cl2N2
- cis-8-Methyl-3,8-diazabicyclo[4.2.0]octane hydrochloride2375165-49-2C7H15ClN2
- (1R,6S)-8-Methyl-3,8-diazabicyclo[4.2.0]octane dihydrochloride2135331-77-8C7H16Cl2N2
- (1R,6S)-4-Methyl-4,7-diazabicyclo[4.2.0]octane dihydrochlorideC7H16Cl2N2
- (1R,6S)-3-Methyl-3,8-diazabicyclo[4.2.0]octane hydrochloride2445226-33-3C7H15ClN2
- 3-Methyl-3,8-diazabicyclo[4.2.0]octane, dihydrochlorideC7H16Cl2N2
- (1S,6R)-8-Methyl-3,8-diazabicyclo[4.2.0]octane bis(2,2,2-trifluoroacetate)2227198-51-6C11H16F6N2O4
- tert-Butyl 3,8-diazabicyclo[4.2.0]octane-8-carboxylate hcl2639625-51-5C11H21ClN2O2
- (1S,6R)-8-Methyl-3,8-diazabicyclo[4.2.0]octane hydrochloride2306253-35-8C7H15ClN2
- (1S,6R)-3-Methyl-3,8-diazabicyclo[4.2.0]octane bis(2,2,2-trifluoroacetate)3026596-54-0C11H16F6N2O4
- (1R,6S)-3-Methyl-3,8-diazabicyclo[4.2.0]octane, bis(2,2,2-trifluoroacetic acid)3037659-79-0C11H16F6N2O4
- rac-Prop-2-en-1-yl (1R,6S)-3,8-diazabicyclo[4.2.0]octane-8-carboxylate2679859-97-1C10H16N2O2
Related scaffolds
Same ring framework with different atoms or bond orders
