Murcko scaffold
2,5-Diazabicyclo[4.2.0]octane scaffold
23 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 8
- Chemicals
- 23
- With full pages
- 4
Scaffold SMILES
C1CNC2CCC2N1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 23 of 23 chemicals
![2,5-Diazabicyclo[4.2.0]octane chemical structure, C6H12N2, CAS 51272-72-1](/s/YHUBPQNUZGPHRQ-UHFFFAOYSA-N.svg)
2,5-Diazabicyclo[4.2.0]octane
CAS 51272-72-1C6H12N2
![2-Methyl-2,5-diazabicyclo[4.2.0]octane chemical structure, C7H14N2, CAS 1780899-23-1](/s/HFDCQULRGXUUDZ-UHFFFAOYSA-N.svg)
2-Methyl-2,5-diazabicyclo[4.2.0]octane
CAS 1780899-23-1C7H14N2
![tert-Butyl 2,5-diazabicyclo[4.2.0]octane-2-carboxylate chemical structure, C11H20N2O2, CAS 1314401-91-6](/s/JIIFXMDXOJFVMW-UHFFFAOYSA-N.svg)
tert-Butyl 2,5-diazabicyclo[4.2.0]octane-2-carboxylate
CAS 1314401-91-6C11H20N2O2
![2,5-Diazabicyclo[4.2.0]octane bis(2,2,2-trifluoroacetate) chemical structure, C10H14F6N2O4, CAS 936706-47-7](/s/UJBWUXIXNDMRGF-UHFFFAOYSA-N.svg)
2,5-Diazabicyclo[4.2.0]octane bis(2,2,2-trifluoroacetate)
CAS 936706-47-7C10H14F6N2O4
![2-Methyl-2,5-diazabicyclo[4.2.0]octane dihydrochloride chemical structure, C7H16Cl2N2, CAS 2306263-54-5](/s/HVGOESCUNGJJQE-UHFFFAOYSA-N.svg)
2-Methyl-2,5-diazabicyclo[4.2.0]octane dihydrochloride
CAS 2306263-54-5C7H16Cl2N2
rac-tert-Butyl (1R,6S)-2,5-diazabicyclo(4.2.0)octane-2-carboxylate
CAS 2343964-43-0C11H20N2O2
![2,5-Diazabicyclo[4.2.0]octane dihydrochloride chemical structure, C6H14Cl2N2, CAS 2361645-30-7](/s/YDHHOMAODDKZOZ-UHFFFAOYSA-N.svg)
2,5-Diazabicyclo[4.2.0]octane dihydrochloride
CAS 2361645-30-7C6H14Cl2N2
![rac-(1R,6S)-2-Methyl-2,5-diazabicyclo[4.2.0]octane dihydrochloride chemical structure, C7H16Cl2N2, CAS 2470280-37-4](/s/HVGOESCUNGJJQE-VJBFUYBPSA-N.svg)
rac-(1R,6S)-2-Methyl-2,5-diazabicyclo[4.2.0]octane dihydrochloride
CAS 2470280-37-4C7H16Cl2N2
![tert-Butyl cis-2,5-diazabicyclo[4.2.0]octane-2-carboxylate chemical structure, C11H20N2O2, CAS 2514607-31-7](/s/JIIFXMDXOJFVMW-DTWKUNHWSA-N.svg)
tert-Butyl cis-2,5-diazabicyclo[4.2.0]octane-2-carboxylate
CAS 2514607-31-7C11H20N2O2
![rac-(1R,6R)-2-Methyl-2,5-diazabicyclo[4.2.0]octane dihydrochloride chemical structure, C7H16Cl2N2, CAS 2648902-21-8](/s/HVGOESCUNGJJQE-GPJOBVNKSA-N.svg)
rac-(1R,6R)-2-Methyl-2,5-diazabicyclo[4.2.0]octane dihydrochloride
CAS 2648902-21-8C7H16Cl2N2
![rac-(1R,6R)-2-Methyl-2,5-diazabicyclo[4.2.0]octane chemical structure, C7H14N2, CAS 2648851-93-6](/s/HFDCQULRGXUUDZ-RNFRBKRXSA-N.svg)
rac-(1R,6R)-2-Methyl-2,5-diazabicyclo[4.2.0]octane
CAS 2648851-93-6C7H14N2
![rac-(1R,6R)-2,5-Diazabicyclo[4.2.0]octane dihydrochloride chemical structure, C6H14Cl2N2, CAS 2763585-01-7](/s/YDHHOMAODDKZOZ-USPAICOZSA-N.svg)
rac-(1R,6R)-2,5-Diazabicyclo[4.2.0]octane dihydrochloride
CAS 2763585-01-7C6H14Cl2N2
![(1S,6S)-2,5-Diazabicyclo[4.2.0]octane chemical structure, C6H12N2, CAS 2763585-00-6](/s/YHUBPQNUZGPHRQ-WDSKDSINSA-N.svg)
(1S,6S)-2,5-Diazabicyclo[4.2.0]octane
CAS 2763585-00-6C6H12N2
![rac-tert-Butyl (1R,6R)-2,5-diazabicyclo[4.2.0]octane-2-carboxylate chemical structure, C11H20N2O2, CAS 2865073-18-1](/s/JIIFXMDXOJFVMW-RKDXNWHRSA-N.svg)
rac-tert-Butyl (1R,6R)-2,5-diazabicyclo[4.2.0]octane-2-carboxylate
CAS 2865073-18-1C11H20N2O2
![cis-2-Methyl-2,5-diazabicyclo[4.2.0]octane 2hcl chemical structure, C7H16Cl2N2, CAS 2708281-36-9](/s/HVGOESCUNGJJQE-AUCRBCQYSA-N.svg)
cis-2-Methyl-2,5-diazabicyclo[4.2.0]octane 2hcl
CAS 2708281-36-9C7H16Cl2N2
![rac-(1R,6S)-2-Methyl-2,5-diazabicyclo[4.2.0]octane chemical structure, C7H14N2, CAS 2470280-10-3](/s/HFDCQULRGXUUDZ-NKWVEPMBSA-N.svg)
rac-(1R,6S)-2-Methyl-2,5-diazabicyclo[4.2.0]octane
CAS 2470280-10-3C7H14N2
![trans-2,5-Diazabicyclo[4.2.0]octane dihydrochloride chemical structure, C6H14Cl2N2, CAS 2648895-50-3](/s/YDHHOMAODDKZOZ-BNTLRKBRSA-N.svg)
trans-2,5-Diazabicyclo[4.2.0]octane dihydrochloride
CAS 2648895-50-3C6H14Cl2N2
![rac-(1R,6R)-2,5-Diazabicyclo[4.2.0]octane chemical structure, C6H12N2, CAS 2648862-68-2](/s/YHUBPQNUZGPHRQ-PHDIDXHHSA-N.svg)
rac-(1R,6R)-2,5-Diazabicyclo[4.2.0]octane
CAS 2648862-68-2C6H12N2
![cis-2,5-Diazabicyclo[4.2.0]octane, dihydrochloride chemical structure, C6H14Cl2N2, CAS 2566777-95-3](/s/YDHHOMAODDKZOZ-RUTFAPCESA-N.svg)
cis-2,5-Diazabicyclo[4.2.0]octane, dihydrochloride
CAS 2566777-95-3C6H14Cl2N2
![(1R,6S)-2,5-Diazabicyclo[4.2.0]octane chemical structure, C6H12N2, CAS 2566777-94-2](/s/YHUBPQNUZGPHRQ-OLQVQODUSA-N.svg)
(1R,6S)-2,5-Diazabicyclo[4.2.0]octane
CAS 2566777-94-2C6H12N2
![tert-Butyl (1S,6S)-2,5-diazabicyclo[4.2.0]octane-2-carboxylate chemical structure, C11H20N2O2, CAS 2920219-11-8](/s/JIIFXMDXOJFVMW-IUCAKERBSA-N.svg)
tert-Butyl (1S,6S)-2,5-diazabicyclo[4.2.0]octane-2-carboxylate
CAS 2920219-11-8C11H20N2O2
![Ditert-butyl cis-2,5-diazabicyclo[4.2.0]octane-2,5-dicarboxylate chemical structure, C16H28N2O4, CAS 2816820-25-2](/s/NOJMPXVRVLVZAC-TXEJJXNPSA-N.svg)
Ditert-butyl cis-2,5-diazabicyclo[4.2.0]octane-2,5-dicarboxylate
CAS 2816820-25-2C16H28N2O4
![2,5-Diazabicyclo[4.2.0]octane-2-carboxylic acid, 7-(trifluoromethyl)-, 1,1-dimet inverted exclamation mark- chemical structure, C12H19F3N2O2, CAS 3033418-25-3](/s/HGUSTFAUWDKIEA-DJLDLDEBSA-N.svg)
2,5-Diazabicyclo[4.2.0]octane-2-carboxylic acid, 7-(trifluoromethyl)-, 1,1-dimet inverted exclamation mark-
CAS 3033418-25-3C12H19F3N2O2
Related scaffolds
Same ring framework with different atoms or bond orders
