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Murcko scaffold

Urea, N-phenyl-N'-1,3,4-thiadiazol-2-yl- scaffold

126 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
126
With full pages
19
Scaffold SMILES

O=C(Nc1ccccc1)Nc1nncs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Urea, N-phenyl-N'-1,3,4-thiadiazol-2-yl- page
Murcko scaffold O=C(Nc1ccccc1)Nc1nncs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 126 chemicals

Urea, N-phenyl-N'-1,3,4-thiadiazol-2-yl- chemical structure, C9H8N4OS, CAS 41118-83-6
Urea, N-phenyl-N'-1,3,4-thiadiazol-2-yl-
CAS 41118-83-6C9H8N4OS
Benzoic acid, 4-[[(1,3,4-thiadiazol-2-ylamino)carbonyl]amino]-, ethyl ester chemical structure, C12H12N4O3S, CAS 69123-49-5
Benzoic acid, 4-[[(1,3,4-thiadiazol-2-ylamino)carbonyl]amino]-, ethyl ester
CAS 69123-49-5C12H12N4O3S
1-(4-Nitrophenyl)-3-(1,3,4-thiadiazol-2-yl)urea chemical structure, C9H7N5O3S, CAS 69123-62-2
1-(4-Nitrophenyl)-3-(1,3,4-thiadiazol-2-yl)urea
CAS 69123-62-2C9H7N5O3S
RefChem:357123 chemical structure, C14H18N4O2S, CAS 113589-74-5
RefChem:357123
CAS 113589-74-5C14H18N4O2S
1-(5-Ethyl-1,3,4-thiadiazol-2-yl)-3-phenylurea chemical structure, C11H12N4OS, CAS 69378-05-8
1-(5-Ethyl-1,3,4-thiadiazol-2-yl)-3-phenylurea
CAS 69378-05-8C11H12N4OS
1-(3-Chlorophenyl)-3-(5-methyl-1,3,4-thiadiazol-2-yl)urea chemical structure, C10H9ClN4OS, CAS 197512-45-1
1-(3-Chlorophenyl)-3-(5-methyl-1,3,4-thiadiazol-2-yl)urea
CAS 197512-45-1C10H9ClN4OS
1-(4-Fluorophenyl)-3-(5-propylsulfanyl-1,3,4-thiadiazol-2-yl)urea chemical structure, C12H13FN4OS2, CAS 487038-54-0
1-(4-Fluorophenyl)-3-(5-propylsulfanyl-1,3,4-thiadiazol-2-yl)urea
CAS 487038-54-0C12H13FN4OS2
1-Phenyl-3-(5-(propylthio)-1,3,4-thiadiazol-2-yl)urea chemical structure, C12H14N4OS2, CAS 497940-70-2
1-Phenyl-3-(5-(propylthio)-1,3,4-thiadiazol-2-yl)urea
CAS 497940-70-2C12H14N4OS2
1-(4-Fluorophenyl)-3-(1,3,4-thiadiazol-2-yl)urea chemical structure, C9H7FN4OS, CAS 718624-41-0
1-(4-Fluorophenyl)-3-(1,3,4-thiadiazol-2-yl)urea
CAS 718624-41-0C9H7FN4OS
1-(5-Methyl-1,3,4-thiadiazol-2-yl)-3-phenylurea chemical structure, C10H10N4OS, CAS 41148-20-3
1-(5-Methyl-1,3,4-thiadiazol-2-yl)-3-phenylurea
CAS 41148-20-3C10H10N4OS
1-(4-Chlorophenyl)-3-(5-methyl-1,3,4-thiadiazol-2-yl)urea chemical structure, C10H9ClN4OS, CAS 53532-42-6
1-(4-Chlorophenyl)-3-(5-methyl-1,3,4-thiadiazol-2-yl)urea
CAS 53532-42-6C10H9ClN4OS
1-(3,4-Dichlorophenyl)-3-(5-propyl-1,3,4-thiadiazol-2-yl)urea chemical structure, C12H12Cl2N4OS, CAS 356780-12-6
1-(3,4-Dichlorophenyl)-3-(5-propyl-1,3,4-thiadiazol-2-yl)urea
CAS 356780-12-6C12H12Cl2N4OS
1-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-3-(4-chlorophenyl)urea chemical structure, C13H15ClN4OS, CAS 28235-84-9
1-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-3-(4-chlorophenyl)urea
CAS 28235-84-9C13H15ClN4OS
Ethyl 2-[5-[(4-chlorophenyl)carbamoylamino]-1,3,4-thiadiazol-2-yl]acetate chemical structure, C13H13ClN4O3S, CAS 5573-64-8
Ethyl 2-[5-[(4-chlorophenyl)carbamoylamino]-1,3,4-thiadiazol-2-yl]acetate
CAS 5573-64-8C13H13ClN4O3S
1-(3,4-Dichlorophenyl)-3-[(2E)-5-ethyl-1,3,4-thiadiazol-2(3H)-ylidene]urea chemical structure, C11H10Cl2N4OS, CAS 356780-11-5
1-(3,4-Dichlorophenyl)-3-[(2E)-5-ethyl-1,3,4-thiadiazol-2(3H)-ylidene]urea
CAS 356780-11-5C11H10Cl2N4OS
1-(4-Methoxyphenyl)-3-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]urea chemical structure, C14H18N4O2S, CAS 356780-24-0
1-(4-Methoxyphenyl)-3-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]urea
CAS 356780-24-0C14H18N4O2S
1-(4-Chlorophenyl)-3-(5-ethyl-1,3,4-thiadiazol-2-yl)urea chemical structure, C11H11ClN4OS, CAS 53532-44-8
1-(4-Chlorophenyl)-3-(5-ethyl-1,3,4-thiadiazol-2-yl)urea
CAS 53532-44-8C11H11ClN4OS
1-(4-Chlorophenyl)-3-(5-propyl-1,3,4-thiadiazol-2-yl)urea chemical structure, C12H13ClN4OS, CAS 5553-22-0
1-(4-Chlorophenyl)-3-(5-propyl-1,3,4-thiadiazol-2-yl)urea
CAS 5553-22-0C12H13ClN4OS
1-(3,4-Dichlorophenyl)-3-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]urea chemical structure, C13H14Cl2N4OS, CAS 356780-14-8
1-(3,4-Dichlorophenyl)-3-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]urea
CAS 356780-14-8C13H14Cl2N4OS
1-(3,4-Dichloro-phenyl)-3-(5-methyl-[1,3,4]thiadiazol-2-yl)-urea chemical structure, C10H8Cl2N4OS, CAS 61516-60-7
1-(3,4-Dichloro-phenyl)-3-(5-methyl-[1,3,4]thiadiazol-2-yl)-urea
CAS 61516-60-7C10H8Cl2N4OS
1-(4-Fluorophenyl)-3-(5-propyl-1,3,4-thiadiazol-2-yl)urea chemical structure, C12H13FN4OS, CAS 426234-83-5
1-(4-Fluorophenyl)-3-(5-propyl-1,3,4-thiadiazol-2-yl)urea
CAS 426234-83-5C12H13FN4OS
1-(4-Fluorophenyl)-3-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)urea chemical structure, C12H13FN4OS, CAS 426251-65-2
1-(4-Fluorophenyl)-3-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)urea
CAS 426251-65-2C12H13FN4OS
1-(4-Fluorophenyl)-3-(5-methyl-1,3,4-thiadiazol-2-yl)urea chemical structure, C10H9FN4OS, CAS 426242-17-3
1-(4-Fluorophenyl)-3-(5-methyl-1,3,4-thiadiazol-2-yl)urea
CAS 426242-17-3C10H9FN4OS
1-(5-Ethyl-1,3,4-thiadiazol-2-yl)-3-(4-fluorophenyl)urea chemical structure, C11H11FN4OS, CAS 426243-07-4
1-(5-Ethyl-1,3,4-thiadiazol-2-yl)-3-(4-fluorophenyl)urea
CAS 426243-07-4C11H11FN4OS