Murcko scaffold
Ring system with 4 rings and 25 atoms
21 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 25
- Chemicals
- 21
- With full pages
- 1
Scaffold SMILES
O=C(NCCn1cncn1)OCC1c2ccccc2-c2ccccc21
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 21 of 21 chemicals
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(1H-1,2,4-triazol-1-yl)propanoic acid
CAS 1217449-37-0C20H18N4O4
![2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1H-1,2,4-triazol-1-yl)propanoic acid chemical structure, C20H18N4O4, CAS 224173-51-7](/s/XGPCEHLWWDGWIG-UHFFFAOYSA-N.svg)
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1H-1,2,4-triazol-1-yl)propanoic acid
CAS 224173-51-7C20H18N4O4
![2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-methyl-3-(1H-1,2,4-triazol-1-yl)propanoic acid chemical structure, C21H20N4O4, CAS 2138029-19-1](/s/LLOZUWDPVYGOCR-UHFFFAOYSA-N.svg)
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-methyl-3-(1H-1,2,4-triazol-1-yl)propanoic acid
CAS 2138029-19-1C21H20N4O4
![3-(3,5-Dimethyl-1H-1,2,4-triazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpropanoic acid chemical structure, C23H24N4O4, CAS 2138521-44-3](/s/ATJJAMCWWHWMCI-UHFFFAOYSA-N.svg)
3-(3,5-Dimethyl-1H-1,2,4-triazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpropanoic acid
CAS 2138521-44-3C23H24N4O4
![3-(3,5-Diethyl-1H-1,2,4-triazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid chemical structure, C25H28N4O4, CAS 2137473-65-3](/s/UGZKQHLXKVXQQJ-UHFFFAOYSA-N.svg)
3-(3,5-Diethyl-1H-1,2,4-triazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid
CAS 2137473-65-3C25H28N4O4
![3-(3,5-Diethyl-1H-1,2,4-triazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpropanoic acid chemical structure, C25H28N4O4, CAS 2138076-43-2](/s/ILXFHXANZPMFMK-UHFFFAOYSA-N.svg)
3-(3,5-Diethyl-1H-1,2,4-triazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpropanoic acid
CAS 2138076-43-2C25H28N4O4
![2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-methyl-3-[3-(propan-2-yl)-1H-1,2,4-triazol-1-yl]propanoic acid chemical structure, C24H26N4O4, CAS 2138110-18-4](/s/IZOZFXVMQATQQW-UHFFFAOYSA-N.svg)
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-methyl-3-[3-(propan-2-yl)-1H-1,2,4-triazol-1-yl]propanoic acid
CAS 2138110-18-4C24H26N4O4
![2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-[3-(propan-2-yl)-1H-1,2,4-triazol-1-yl]butanoic acid chemical structure, C24H26N4O4, CAS 2137489-86-0](/s/WAARWXQVCIQYEE-UHFFFAOYSA-N.svg)
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-[3-(propan-2-yl)-1H-1,2,4-triazol-1-yl]butanoic acid
CAS 2137489-86-0C24H26N4O4
![3-(3-tert-Butyl-1H-1,2,4-triazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid chemical structure, C25H28N4O4, CAS 2137540-11-3](/s/XBTFEWSGFHMJLY-UHFFFAOYSA-N.svg)
3-(3-tert-Butyl-1H-1,2,4-triazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid
CAS 2137540-11-3C25H28N4O4
![3-(3-tert-Butyl-1H-1,2,4-triazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C24H26N4O4, CAS 2137483-67-9](/s/JYKAVJUSKNSBRG-UHFFFAOYSA-N.svg)
3-(3-tert-Butyl-1H-1,2,4-triazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 2137483-67-9C24H26N4O4
![(2R)-2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1H-1,2,4-triazol-1-yl)propanoic acid chemical structure, C20H18N4O4, CAS 2219354-00-2](/s/XGPCEHLWWDGWIG-GOSISDBHSA-N.svg)
(2R)-2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1H-1,2,4-triazol-1-yl)propanoic acid
CAS 2219354-00-2C20H18N4O4
![1-[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)ethyl]-1H-1,2,4-triazole-5-carboxylic acid chemical structure, C20H18N4O4, CAS 2757926-05-7](/s/KMJWFJPSNHVEOX-UHFFFAOYSA-N.svg)
1-[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)ethyl]-1H-1,2,4-triazole-5-carboxylic acid
CAS 2757926-05-7C20H18N4O4
![3-(Dimethyl-1H-1,2,4-triazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C22H22N4O4, CAS 2137513-68-7](/s/FZGOFHYPNHTRGW-UHFFFAOYSA-N.svg)
3-(Dimethyl-1H-1,2,4-triazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 2137513-68-7C22H22N4O4
![2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-[3-(propan-2-yl)-1H-1,2,4-triazol-1-yl]propanoic acid chemical structure, C23H24N4O4, CAS 2137477-96-2](/s/UMDCFNLGCNDUHE-UHFFFAOYSA-N.svg)
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-[3-(propan-2-yl)-1H-1,2,4-triazol-1-yl]propanoic acid
CAS 2137477-96-2C23H24N4O4
![3-(3,5-Diethyl-1H-1,2,4-triazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C24H26N4O4, CAS 2137512-94-6](/s/BTTGYENHCHTSDS-UHFFFAOYSA-N.svg)
3-(3,5-Diethyl-1H-1,2,4-triazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 2137512-94-6C24H26N4O4
![3-(3,5-Dimethyl-1H-1,2,4-triazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid chemical structure, C23H24N4O4, CAS 2137477-44-0](/s/PRBICSMEUSGUFN-UHFFFAOYSA-N.svg)
3-(3,5-Dimethyl-1H-1,2,4-triazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid
CAS 2137477-44-0C23H24N4O4
![2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1H-1,2,4-triazol-1-yl)butanoic acid chemical structure, C21H20N4O4, CAS 2137471-60-2](/s/ODSHBHCDJOHCQK-UHFFFAOYSA-N.svg)
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1H-1,2,4-triazol-1-yl)butanoic acid
CAS 2137471-60-2C21H20N4O4
![3-(3-tert-Butyl-1H-1,2,4-triazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpropanoic acid chemical structure, C25H28N4O4, CAS 2138069-71-1](/s/LEEJJIBWEYHNDD-UHFFFAOYSA-N.svg)
3-(3-tert-Butyl-1H-1,2,4-triazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpropanoic acid
CAS 2138069-71-1C25H28N4O4
![1-[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)ethyl]-1H-1,2,4-triazole-3-carboxylic acid chemical structure, C20H18N4O4, CAS 2580249-46-1](/s/UFTMCSPTABRDMZ-UHFFFAOYSA-N.svg)
1-[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)ethyl]-1H-1,2,4-triazole-3-carboxylic acid
CAS 2580249-46-1C20H18N4O4
![2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}(methyl)amino)-3-(1H-1,2,4-triazol-1-yl)propanoic acid chemical structure, C21H20N4O4, CAS 2580177-81-5](/s/OOXFFLPEJAWCTO-UHFFFAOYSA-N.svg)
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}(methyl)amino)-3-(1H-1,2,4-triazol-1-yl)propanoic acid
CAS 2580177-81-5C21H20N4O4
![1-[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}(methyl)amino)ethyl]-1H-1,2,4-triazole-5-carboxylic acid chemical structure, C21H20N4O4, CAS 2913415-54-8](/s/WQKSFMUSNHOBFV-UHFFFAOYSA-N.svg)
1-[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}(methyl)amino)ethyl]-1H-1,2,4-triazole-5-carboxylic acid
CAS 2913415-54-8C21H20N4O4
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(NCCc1nccs1)OCC1c2ccccc2-c2ccccc217 chemicals![Scaffold O=C(NCCc1c[nH]cn1)OCC1c2ccccc2-c2ccccc21](/scaffold/YSCVHHRVDCKDEK-UHFFFAOYSA-N/structure.svg)
O=C(NCCc1c[nH]cn1)OCC1c2ccccc2-c2ccccc215 chemicals
O=C(NCC(=O)N1CCOC1)OCC1c2ccccc2-c2ccccc213 chemicals
O=C(NCCc1cccs1)OCC1c2ccccc2-c2ccccc213 chemicals
O=C(NCCc1ccco1)OCC1c2ccccc2-c2ccccc213 chemicals
O=C(NCCn1cccn1)OCC1c2ccccc2-c2ccccc212 chemicals
O=C(CCn1c2c(c3ccccc31)CCCC2)NN=Cc1ccco12 chemicals
O=C(NCCc1cscn1)OCC1c2ccccc2-c2ccccc212 chemicals
O=C(NCCC1CCCC1)OCC1c2ccccc2-c2ccccc212 chemicals
O=C(NCCc1ccsc1)OCC1c2ccccc2-c2ccccc212 chemicals![Scaffold O=C(NCCc1cn[nH]c1)OCC1c2ccccc2-c2ccccc21](/scaffold/ZXNLBXPPRVWTTQ-UHFFFAOYSA-N/structure.svg)
O=C(NCCc1cn[nH]c1)OCC1c2ccccc2-c2ccccc212 chemicals![Scaffold O=C(NCCc1c[nH]c(=O)[nH]1)OCC1c2ccccc2-c2ccccc21](/scaffold/DXVOSQOYLKBPSU-UHFFFAOYSA-N/structure.svg)
O=C(NCCc1c[nH]c(=O)[nH]1)OCC1c2ccccc2-c2ccccc211 chemical