Murcko scaffold
Ring system with 4 rings and 25 atoms
78 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 25
- Chemicals
- 78
- With full pages
- 2
Scaffold SMILES
O=C(NCCn1cccn1)OCC1c2ccccc2-c2ccccc21
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 78 chemicals
Fmoc-3-(Pyrazol-1-yl)-L-Ala-OH
CAS 1217450-35-5C21H19N3O4
Fmoc-D-ala(1-pyrazolyl)-OH
CAS 948594-98-7C21H19N3O4
![2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1H-pyrazol-1-yl)propanoic acid chemical structure, C21H19N3O4, CAS 224173-50-6](/s/LFIMKADLAIDVGC-UHFFFAOYSA-N.svg)
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1H-pyrazol-1-yl)propanoic acid
CAS 224173-50-6C21H19N3O4
![2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-[3-(trifluoromethyl)-1H-pyrazol-1-yl]propanoic acid chemical structure, C22H18F3N3O4, CAS 2137448-31-6](/s/ACNLZHGQCZXOSU-UHFFFAOYSA-N.svg)
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-[3-(trifluoromethyl)-1H-pyrazol-1-yl]propanoic acid
CAS 2137448-31-6C22H18F3N3O4
![2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(3,4,5-trimethyl-1H-pyrazol-1-yl)propanoic acid chemical structure, C24H25N3O4, CAS 2137449-99-9](/s/VEAQKXULUVWFAL-UHFFFAOYSA-N.svg)
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(3,4,5-trimethyl-1H-pyrazol-1-yl)propanoic acid
CAS 2137449-99-9C24H25N3O4
![3-(4-Chloro-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C21H18ClN3O4, CAS 2137517-20-3](/s/COAZNNHPIIKAGL-UHFFFAOYSA-N.svg)
3-(4-Chloro-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 2137517-20-3C21H18ClN3O4
![2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(4-methyl-1H-pyrazol-1-yl)propanoic acid chemical structure, C22H21N3O4, CAS 224173-59-5](/s/SCWSWGQXFISKLX-UHFFFAOYSA-N.svg)
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(4-methyl-1H-pyrazol-1-yl)propanoic acid
CAS 224173-59-5C22H21N3O4
![3-(4-Bromo-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C21H18BrN3O4, CAS 224173-61-9](/s/QUCDGTOVUPWZGR-UHFFFAOYSA-N.svg)
3-(4-Bromo-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 224173-61-9C21H18BrN3O4
![2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-methyl-3-(1H-pyrazol-1-yl)propanoic acid chemical structure, C22H21N3O4, CAS 2137559-45-4](/s/CLHMTPRJRUKHOF-UHFFFAOYSA-N.svg)
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-methyl-3-(1H-pyrazol-1-yl)propanoic acid
CAS 2137559-45-4C22H21N3O4
![3-(4-Bromo-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpropanoic acid chemical structure, C22H20BrN3O4, CAS 2138526-01-7](/s/UOMVGXMCUQNTEG-UHFFFAOYSA-N.svg)
3-(4-Bromo-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpropanoic acid
CAS 2138526-01-7C22H20BrN3O4
![3-(3,5-Dimethyl-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C23H23N3O4, CAS 2137510-44-0](/s/HPVXFJQRBYFAAS-UHFFFAOYSA-N.svg)
3-(3,5-Dimethyl-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 2137510-44-0C23H23N3O4
![3-(3,5-Diethyl-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpropanoic acid chemical structure, C26H29N3O4, CAS 2138550-41-9](/s/GWUZAHXZFHMAFP-UHFFFAOYSA-N.svg)
3-(3,5-Diethyl-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpropanoic acid
CAS 2138550-41-9C26H29N3O4
![2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-methyl-3-[4-(propan-2-yloxy)-1H-pyrazol-1-yl]propanoic acid chemical structure, C25H27N3O5, CAS 2138521-52-3](/s/YJLHGZAVFSOWOM-UHFFFAOYSA-N.svg)
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-methyl-3-[4-(propan-2-yloxy)-1H-pyrazol-1-yl]propanoic acid
CAS 2138521-52-3C25H27N3O5
2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-iodo-1H-pyrazol-1-yl)propanoic acid
CAS 2137473-26-6C21H18IN3O4
![2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(4-methoxy-1H-pyrazol-1-yl)propanoic acid chemical structure, C22H21N3O5, CAS 2137478-41-0](/s/JDFQHIYTGODKNL-UHFFFAOYSA-N.svg)
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(4-methoxy-1H-pyrazol-1-yl)propanoic acid
CAS 2137478-41-0C22H21N3O5
![3-(4-Ethoxy-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C23H23N3O5, CAS 2137492-55-6](/s/WVPNGDGSFVATMO-UHFFFAOYSA-N.svg)
3-(4-Ethoxy-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 2137492-55-6C23H23N3O5
![3-(4-Ethyl-3,5-dimethyl-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C25H27N3O4, CAS 2137473-40-4](/s/SISWRJNFDIZYLU-UHFFFAOYSA-N.svg)
3-(4-Ethyl-3,5-dimethyl-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 2137473-40-4C25H27N3O4
![2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-methyl-3-[4-(propan-2-yl)-1H-pyrazol-1-yl]propanoic acid chemical structure, C25H27N3O4, CAS 2138044-76-3](/s/JSWXIWJHEONUTI-UHFFFAOYSA-N.svg)
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-methyl-3-[4-(propan-2-yl)-1H-pyrazol-1-yl]propanoic acid
CAS 2138044-76-3C25H27N3O4
![3-(3,5-Dimethyl-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid chemical structure, C24H25N3O4, CAS 2137492-59-0](/s/UOFWANDTLASMKX-UHFFFAOYSA-N.svg)
3-(3,5-Dimethyl-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid
CAS 2137492-59-0C24H25N3O4
![2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(4-methoxy-1H-pyrazol-1-yl)butanoic acid chemical structure, C23H23N3O5, CAS 2137472-30-9](/s/BDJCTYMJJIKTGA-UHFFFAOYSA-N.svg)
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(4-methoxy-1H-pyrazol-1-yl)butanoic acid
CAS 2137472-30-9C23H23N3O5
![3-(4-Ethoxy-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid chemical structure, C24H25N3O5, CAS 2137472-35-4](/s/QVPCQJRRJYYYNC-UHFFFAOYSA-N.svg)
3-(4-Ethoxy-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid
CAS 2137472-35-4C24H25N3O5
![3-(4-Bromo-3,5-dimethyl-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpropanoic acid chemical structure, C24H24BrN3O4, CAS 2138547-47-2](/s/QDNUWRQVUHMWLZ-UHFFFAOYSA-N.svg)
3-(4-Bromo-3,5-dimethyl-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpropanoic acid
CAS 2138547-47-2C24H24BrN3O4
![3-(4-Ethyl-3,5-dimethyl-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpropanoic acid chemical structure, C26H29N3O4, CAS 2138071-26-6](/s/QZAPUUCTDJITEN-UHFFFAOYSA-N.svg)
3-(4-Ethyl-3,5-dimethyl-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpropanoic acid
CAS 2138071-26-6C26H29N3O4
![2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-methyl-3-[3-(trifluoromethyl)-1H-pyrazol-1-yl]propanoic acid chemical structure, C23H20F3N3O4, CAS 2138547-65-4](/s/YCBURJBLRPXLER-UHFFFAOYSA-N.svg)
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-methyl-3-[3-(trifluoromethyl)-1H-pyrazol-1-yl]propanoic acid
CAS 2138547-65-4C23H20F3N3O4
- 3-(3,5-Dimethyl-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpropanoic acid2138104-47-7C24H25N3O4
- 2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(4-methoxy-1H-pyrazol-1-yl)-2-methylpropanoic acid2138567-14-1C23H23N3O5
- 3-(4-Chloro-3-methyl-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpropanoic acid2138569-05-6C23H22ClN3O4
- 3-(4-Chloro-3,5-dimethyl-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid2137566-87-9C24H24ClN3O4
- 2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(4-propoxy-1H-pyrazol-1-yl)butanoic acid2137566-91-5C25H27N3O5
- 2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-[3-(trifluoromethyl)-1H-pyrazol-1-yl]butanoic acid2137477-22-4C23H20F3N3O4
- 2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(5-methyl-1H-pyrazol-1-yl)propanoic acid224173-57-3C22H21N3O4
- 2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(3-methyl-1H-pyrazol-1-yl)propanoic acid224173-56-2C22H21N3O4
- 3-(4-Chloro-5-methyl-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid2137531-11-2C22H20ClN3O4
- 3-(4-Chloro-3,5-dimethyl-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid2137477-37-1C23H22ClN3O4
- 2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-[4-(propan-2-yloxy)-1H-pyrazol-1-yl]propanoic acid2137477-41-7C24H25N3O5
- 2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-[4-(trifluoromethyl)-1H-pyrazol-1-yl]propanoic acid2137516-41-5C22H18F3N3O4
- 2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(4-propyl-1H-pyrazol-1-yl)propanoic acid2137473-02-8C24H25N3O4
- 3-(4-Ethyl-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid2137482-54-1C23H23N3O4
- 3-(4-Ethyl-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpropanoic acid2138046-97-4C24H25N3O4
- 2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1H-pyrazol-1-yl)butanoic acid2137516-49-3C22H21N3O4
- 2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(5-methyl-1H-pyrazol-1-yl)butanoic acid2137473-04-0C23H23N3O4
- 3-(4-Chloro-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid2137513-69-8C22H20ClN3O4
- 2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(4-iodo-1H-pyrazol-1-yl)butanoic acid2137478-02-3C22H20IN3O4
- 3-(4-Chloro-5-methyl-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid2137478-05-6C23H22ClN3O4
- 3-(4-Chloro-3-methyl-1H-pyrazol-1-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid2137473-31-3C23H22ClN3O4
- 2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-methyl-3-(4-propoxy-1H-pyrazol-1-yl)propanoic acid2138041-17-3C25H27N3O5
- 2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-[4-(propan-2-yl)-1H-pyrazol-1-yl]propanoic acid2137478-00-1C24H25N3O4
- 2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(3-methyl-1H-pyrazol-1-yl)butanoic acid2137477-99-5C23H23N3O4
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(NCCc1nccs1)OCC1c2ccccc2-c2ccccc217 chemicals![Scaffold O=C(NCCc1c[nH]cn1)OCC1c2ccccc2-c2ccccc21](/scaffold/YSCVHHRVDCKDEK-UHFFFAOYSA-N/structure.svg)
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O=C(NCCc1ccsc1)OCC1c2ccccc2-c2ccccc212 chemicals![Scaffold O=C(NCCc1cn[nH]c1)OCC1c2ccccc2-c2ccccc21](/scaffold/ZXNLBXPPRVWTTQ-UHFFFAOYSA-N/structure.svg)
O=C(NCCc1cn[nH]c1)OCC1c2ccccc2-c2ccccc212 chemicals![Scaffold O=C(NCCc1c[nH]c(=O)[nH]1)OCC1c2ccccc2-c2ccccc21](/scaffold/DXVOSQOYLKBPSU-UHFFFAOYSA-N/structure.svg)
O=C(NCCc1c[nH]c(=O)[nH]1)OCC1c2ccccc2-c2ccccc211 chemical
O=C(NCCn1cncn1)OCC1c2ccccc2-c2ccccc211 chemical