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Murcko scaffold

Ring system with 4 rings and 26 atoms

27 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
27
With full pages
3
Scaffold SMILES

O=C(NCC(=O)N1CCOC1)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCC(=O)N1CCOC1)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

(4S)-3-((2S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)propanoyl)-2,2-dimethyl-1,3-oxazolidine-4-carboxylic acid chemical structure, C24H26N2O6, CAS 252554-78-2
(4S)-3-((2S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)propanoyl)-2,2-dimethyl-1,3-oxazolidine-4-carboxylic acid
CAS 252554-78-2C24H26N2O6
4-Oxazolidinecarboxylic acid, 3-((2S)-3-(1,1-dimethylethoxy)-2-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)-1-oxopropyl)-2,2-dimethyl-, (4S)- chemical structure, C28H34N2O7, CAS 1000164-43-1
4-Oxazolidinecarboxylic acid, 3-((2S)-3-(1,1-dimethylethoxy)-2-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)-1-oxopropyl)-2,2-dimethyl-, (4S)-
CAS 1000164-43-1C28H34N2O7
Fmoc-Leucine-Serine Pseudoproline chemical structure, C27H32N2O6, CAS 339531-50-9
Fmoc-Leucine-Serine Pseudoproline
CAS 339531-50-9C27H32N2O6
Fmoc-Ala-Thr(Psi(Me,Me)pro)-OH chemical structure, C25H28N2O6, CAS 252554-79-3
Fmoc-Ala-Thr(Psi(Me,Me)pro)-OH
CAS 252554-79-3C25H28N2O6
Fmoc-Thr(Tbu)-Ser(Psi(Me,Me)Pro)-OH chemical structure, C29H36N2O7, CAS 1425938-63-1
Fmoc-Thr(Tbu)-Ser(Psi(Me,Me)Pro)-OH
CAS 1425938-63-1C29H36N2O7
(R)-3-(N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyl)-D-seryl)-2,2-dimethyloxazolidine-4-carboxylic acid chemical structure, C28H34N2O7, CAS 1522313-26-3
(R)-3-(N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyl)-D-seryl)-2,2-dimethyloxazolidine-4-carboxylic acid
CAS 1522313-26-3C28H34N2O7
Fmoc-Gly-Thr[Psi(Me,Me)Pro]-OH chemical structure, C24H26N2O6, CAS 1262308-49-5
Fmoc-Gly-Thr[Psi(Me,Me)Pro]-OH
CAS 1262308-49-5C24H26N2O6
Fmoc-Gly-Ser(Psi(Me,Me)Pro)-OH chemical structure, C23H24N2O6, CAS 1095952-22-9
Fmoc-Gly-Ser(Psi(Me,Me)Pro)-OH
CAS 1095952-22-9C23H24N2O6
Fmoc-Asp(OtBu)-Ser(Psi(Me,Me)pro)-OH chemical structure, C29H34N2O8, CAS 955048-92-7
Fmoc-Asp(OtBu)-Ser(Psi(Me,Me)pro)-OH
CAS 955048-92-7C29H34N2O8
Fmoc-Asp(Otbu)-Thr(Psime,Mepro)-OH chemical structure, C30H36N2O8, CAS 920519-32-0
Fmoc-Asp(Otbu)-Thr(Psime,Mepro)-OH
CAS 920519-32-0C30H36N2O8
Fmoc-Glu(OtBu)-Ser(Psi(Me,Me)pro)-OH chemical structure, C30H36N2O8, CAS 909115-33-9
Fmoc-Glu(OtBu)-Ser(Psi(Me,Me)pro)-OH
CAS 909115-33-9C30H36N2O8
Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OH chemical structure, C31H38N2O8, CAS 957780-56-2
Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OH
CAS 957780-56-2C31H38N2O8
Fmoc-Ile-Ser(Psi(Me,Me)pro)-OH chemical structure, C27H32N2O6, CAS 1147996-34-6
Fmoc-Ile-Ser(Psi(Me,Me)pro)-OH
CAS 1147996-34-6C27H32N2O6
Fmoc-Ile-Thr(Psi(Me,Me)pro)-OH chemical structure, C28H34N2O6, CAS 957780-52-8
Fmoc-Ile-Thr(Psi(Me,Me)pro)-OH
CAS 957780-52-8C28H34N2O6
Fmoc-Leu-Thr(Psi(Me,Me)pro)-OH chemical structure, C28H34N2O6, CAS 955048-89-2
Fmoc-Leu-Thr(Psi(Me,Me)pro)-OH
CAS 955048-89-2C28H34N2O6
Fmoc-Lys(Boc)-Ser(Psi(Me,Me)pro)-OH chemical structure, C32H41N3O8, CAS 957780-54-0
Fmoc-Lys(Boc)-Ser(Psi(Me,Me)pro)-OH
CAS 957780-54-0C32H41N3O8
Fmoc-Lys(Boc)-Thr(Psime,Mepro)-OH chemical structure, C33H43N3O8, CAS 911838-56-7
Fmoc-Lys(Boc)-Thr(Psime,Mepro)-OH
CAS 911838-56-7C33H43N3O8
Fmoc-Ser(tBu)-Thr(Psi(Me,Me)pro)-OH chemical structure, C29H36N2O7, CAS 1266350-99-5
Fmoc-Ser(tBu)-Thr(Psi(Me,Me)pro)-OH
CAS 1266350-99-5C29H36N2O7
Fmoc-Val-Ser(Psime,Mepro)-OH chemical structure, C26H30N2O6, CAS 186023-49-4
Fmoc-Val-Ser(Psime,Mepro)-OH
CAS 186023-49-4C26H30N2O6
Fmoc-Val-Thr(Psi(Me,Me)pro)-OH chemical structure, C27H32N2O6, CAS 168216-05-5
Fmoc-Val-Thr(Psi(Me,Me)pro)-OH
CAS 168216-05-5C27H32N2O6
Fmoc-L-Met-L-Thr[PSI(Me,Me)Pro]-OH chemical structure, C27H32N2O6S, CAS 1451181-13-7
Fmoc-L-Met-L-Thr[PSI(Me,Me)Pro]-OH
CAS 1451181-13-7C27H32N2O6S
Fmoc-Thr(tBu)-Thr(Psi(Me,Me)pro)-OH chemical structure, C30H38N2O7, CAS 1676104-73-6
Fmoc-Thr(tBu)-Thr(Psi(Me,Me)pro)-OH
CAS 1676104-73-6C30H38N2O7
Fmoc-Gly-D-Ser(psi(Me,Me)-Pro)-OH chemical structure, C23H24N2O6, CAS 1998701-38-4
Fmoc-Gly-D-Ser(psi(Me,Me)-Pro)-OH
CAS 1998701-38-4C23H24N2O6
(4R)-3-[(2R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoyl]-2,2-dimethyl-1,3-oxazolidine-4-carboxylic acid chemical structure, C30H36N2O8, CAS 1988772-01-5
(4R)-3-[(2R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoyl]-2,2-dimethyl-1,3-oxazolidine-4-carboxylic acid
CAS 1988772-01-5C30H36N2O8