Murcko scaffold
Ring system with 4 rings and 25 atoms
56 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 25
- Chemicals
- 56
- With full pages
- 2
Scaffold SMILES
O=C(NCCC1CCCC1)OCC1c2ccccc2-c2ccccc21
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 56 chemicals
![3-Cyclopentyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C23H25NO4, CAS 1219422-04-4](/s/NVZVRXJTMCMDNR-UHFFFAOYSA-N.svg)
3-Cyclopentyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 1219422-04-4C23H25NO4
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-cyclopentylpropanoic acid
CAS 371770-32-0C23H25NO4
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-cyclopentylpropanoic acid
CAS 1262802-59-4C23H25NO4
(S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-cyclopentylpropanoic acid
C23H25NO4
(R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-cyclopentylpropanoic acid
CAS 1260593-09-6C23H25NO4
![3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid chemical structure, C24H27NO4, CAS 2137851-66-0](/s/XZBCPXJZEQAQLM-UHFFFAOYSA-N.svg)
3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid
CAS 2137851-66-0C24H27NO4
2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-cyclopentylpropanoic acid
CAS 1993849-91-4C24H27NO4
(R)-2-Cyclopentyl-3-(9H-fluoren-9-ylmethoxycarbonylamino)-propionic acid
CAS 1260614-56-9C23H25NO4
![2-{[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]oxy}acetic acid chemical structure, C26H30N2O6, CAS 2172435-65-1](/s/RVJDFLGZBKHEFL-UHFFFAOYSA-N.svg)
2-{[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]oxy}acetic acid
CAS 2172435-65-1C26H30N2O6
![2-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N-methylbutanamido]acetic acid chemical structure, C27H32N2O5, CAS 2171943-76-1](/s/UKGHLCBYMKYFGL-UHFFFAOYSA-N.svg)
2-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N-methylbutanamido]acetic acid
CAS 2171943-76-1C27H32N2O5
![4-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]butanoic acid chemical structure, C28H34N2O5, CAS 2172386-77-3](/s/VWLSPWFAYDGBGE-UHFFFAOYSA-N.svg)
4-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]butanoic acid
CAS 2172386-77-3C28H34N2O5
![(2R)-2-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]butanoic acid chemical structure, C28H34N2O5, CAS 2171311-42-3](/s/FLXFIIQTCFWGSM-OPEAARRCSA-N.svg)
(2R)-2-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]butanoic acid
CAS 2171311-42-3C28H34N2O5
![(2R)-2-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-3-hydroxypropanoic acid chemical structure, C27H32N2O6, CAS 2648923-70-8](/s/JWEONFBEKPSGEX-VCUSLETLSA-N.svg)
(2R)-2-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-3-hydroxypropanoic acid
CAS 2648923-70-8C27H32N2O6
![2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1-hydroxycyclopentyl)propanoic acid chemical structure, C23H25NO5, CAS 2171746-25-9](/s/CJEWWOCEEBAFGB-UHFFFAOYSA-N.svg)
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1-hydroxycyclopentyl)propanoic acid
CAS 2171746-25-9C23H25NO5
![3-(1-Cyanocyclopentyl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C24H24N2O4, CAS 2138899-43-9](/s/LOPRSRBRLRCJOR-UHFFFAOYSA-N.svg)
3-(1-Cyanocyclopentyl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 2138899-43-9C24H24N2O4
![(2S)-2-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]butanoic acid chemical structure, C28H34N2O5, CAS 2171446-75-4](/s/FLXFIIQTCFWGSM-BIAFCPFJSA-N.svg)
(2S)-2-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]butanoic acid
CAS 2171446-75-4C28H34N2O5
![2-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]acetic acid chemical structure, C26H30N2O5, CAS 2172272-80-7](/s/ULMZBESGPYQSLF-UHFFFAOYSA-N.svg)
2-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]acetic acid
CAS 2172272-80-7C26H30N2O5
![4-Cyclopentyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid chemical structure, C24H27NO4, CAS 2172310-32-4](/s/PLTYEYOJLQJHSC-UHFFFAOYSA-N.svg)
4-Cyclopentyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid
CAS 2172310-32-4C24H27NO4
![3-(2,2-Difluorocyclopentyl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C23H23F2NO4, CAS 1849953-98-5](/s/CJSKNPPJOLTLQZ-UHFFFAOYSA-N.svg)
3-(2,2-Difluorocyclopentyl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 1849953-98-5C23H23F2NO4
![(2S)-2-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]propanoic acid chemical structure, C27H32N2O5, CAS 2648913-49-7](/s/NZWHKQDQUKTHKW-KKFHFHRHSA-N.svg)
(2S)-2-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]propanoic acid
CAS 2648913-49-7C27H32N2O5
![(2S)-2-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-3-hydroxypropanoic acid chemical structure, C27H32N2O6, CAS 2648937-42-0](/s/JWEONFBEKPSGEX-LUTIACGYSA-N.svg)
(2S)-2-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-3-hydroxypropanoic acid
CAS 2648937-42-0C27H32N2O6
![3-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-2-hydroxypropanoic acid chemical structure, C27H32N2O6, CAS 2172305-59-6](/s/DAVYKWZVLGXDSJ-UHFFFAOYSA-N.svg)
3-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-2-hydroxypropanoic acid
CAS 2172305-59-6C27H32N2O6
![2-[3-Cyclopentyl-N-ethyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]acetic acid chemical structure, C28H34N2O5, CAS 2172208-50-1](/s/ZRRVPHWXOWVDFU-UHFFFAOYSA-N.svg)
2-[3-Cyclopentyl-N-ethyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]acetic acid
CAS 2172208-50-1C28H34N2O5
![3-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N-methylbutanamido]propanoic acid chemical structure, C28H34N2O5, CAS 2171814-64-3](/s/XAMUIAUFMZDNHA-UHFFFAOYSA-N.svg)
3-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N-methylbutanamido]propanoic acid
CAS 2171814-64-3C28H34N2O5
- 3-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-2-methylpropanoic acid2172133-87-6C28H34N2O5
- 3-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]butanoic acid2171910-34-0C28H34N2O5
- 2-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]butanoic acid2171469-21-7C28H34N2O5
- (2S)-2-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N-methylbutanamido]propanoic acid2648913-65-7C28H34N2O5
- 4-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]but-2-enoic acid2172607-57-5C28H32N2O5
- (3R)-3-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]butanoic acid2171339-52-7C28H34N2O5
- 4-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]but-2-ynoic acid2171904-55-3C28H30N2O5
- 2-{[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N-methylbutanamido]oxy}acetic acid2172061-30-0C27H32N2O6
- 4-Cyclopentyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-hydroxybutanoic acid2243503-24-2C24H27NO5
- 1-[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)ethyl]cyclopentane-1-carboxylic acid2758004-44-1C23H25NO4
- 2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1-methoxycyclopentyl)propanoic acid2003998-84-1C24H27NO5
- 2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1-methylcyclopentyl)propanoic acid1869265-86-0C24H27NO4
- 4-Cyclopentyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylbutanoic acid2158761-15-8C25H29NO4
- (2R)-2-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]propanoic acid2648920-39-0C27H32N2O5
- 2-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-2-methylpropanoic acid2172319-93-4C28H34N2O5
- 2-{[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]oxy}propanoic acid2172133-97-8C27H32N2O6
- (2S)-3-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-2-hydroxypropanoic acid2171415-64-6C27H32N2O6
- (3S)-3-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]butanoic acid2171444-53-2C28H34N2O5
- 3-[3-Cyclopentyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]propanoic acid2172030-32-7C27H32N2O5
- 3-(3,3-Difluorocyclopentyl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid1697595-62-2C23H23F2NO4
- (9H-Fluoren-9-yl)methyl N-(2-cyclopentyl-2-hydroxyethyl)carbamate2763984-16-1C22H25NO3
- (9H-Fluoren-9-yl)methyl N-(2-cyclopentyl-2-hydroxypropyl)carbamate2764019-92-1C23H27NO3
- rac-(9H-Fluoren-9-yl)methyl N-{2-[(1R,2S)-2-hydroxycyclopentyl]ethyl}carbamate2764021-22-7C22H25NO3
- rac-(9H-Fluoren-9-yl)methyl N-{2-[(1R,2R)-2-hydroxycyclopentyl]ethyl}carbamate2764008-33-3C22H25NO3
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(NCCc1nccs1)OCC1c2ccccc2-c2ccccc217 chemicals![Scaffold O=C(NCCc1c[nH]cn1)OCC1c2ccccc2-c2ccccc21](/scaffold/YSCVHHRVDCKDEK-UHFFFAOYSA-N/structure.svg)
O=C(NCCc1c[nH]cn1)OCC1c2ccccc2-c2ccccc215 chemicals
O=C(NCC(=O)N1CCOC1)OCC1c2ccccc2-c2ccccc213 chemicals
O=C(NCCc1cccs1)OCC1c2ccccc2-c2ccccc213 chemicals
O=C(NCCc1ccco1)OCC1c2ccccc2-c2ccccc213 chemicals
O=C(NCCn1cccn1)OCC1c2ccccc2-c2ccccc212 chemicals
O=C(CCn1c2c(c3ccccc31)CCCC2)NN=Cc1ccco12 chemicals
O=C(NCCc1cscn1)OCC1c2ccccc2-c2ccccc212 chemicals
O=C(NCCc1ccsc1)OCC1c2ccccc2-c2ccccc212 chemicals![Scaffold O=C(NCCc1cn[nH]c1)OCC1c2ccccc2-c2ccccc21](/scaffold/ZXNLBXPPRVWTTQ-UHFFFAOYSA-N/structure.svg)
O=C(NCCc1cn[nH]c1)OCC1c2ccccc2-c2ccccc212 chemicals![Scaffold O=C(NCCc1c[nH]c(=O)[nH]1)OCC1c2ccccc2-c2ccccc21](/scaffold/DXVOSQOYLKBPSU-UHFFFAOYSA-N/structure.svg)
O=C(NCCc1c[nH]c(=O)[nH]1)OCC1c2ccccc2-c2ccccc211 chemical
O=C(NCCn1cncn1)OCC1c2ccccc2-c2ccccc211 chemical